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The map label for this gene is FwdG

Identifier: 20094961

GI number: 20094961

Start: 1537248

End: 1537487

Strand: Direct

Name: FwdG

Synonym: MK1525

Alternate gene names: 20094961

Gene position: 1537248-1537487 (Clockwise)

Preceding gene: 20094960

Following gene: 20094962

Centisome position: 90.69

GC content: 54.58

Gene sequence:

>240_bases
TTGGTAAAGATAGTCATTCACGAGGAACGTTGTCACGGATGCGGTAACTGCGTGATCGCTTGCCCGGTCAACGCTTGTAA
TTCCCCTAACGTATGGGGCGGAAAGGGTCCCGAAGACGGTGAAGATGTAGTGATCAAGGTCGTGAACGGGACGGTCTCGG
TGATTAACGAGGACCTGTGCGAAGCGTGCATGACCTGCGAACTCGCCTGCCCCGTGGACGCTATCGAGATCAAAACGTAG

Upstream 100 bases:

>100_bases
GTTCTGAAGGTGTCCACCGGCCGTCCACCCGTCCCCGCCGACCCCACTTATTTAACTCCGAGGTGTCGGAGCGGGTGCGA
AGACCGGTGGGGGTCGCGGG

Downstream 100 bases:

>100_bases
GGGAGCCACGAAAGATGGCCGAATTCACCCTGCTCACGGGTCGAACGATCTGGCAGGGTGAAGCTATCGAAACCGACAAG
GCGGGCGAGATCTACCCCAA

Product: ferredoxin

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit G

Number of amino acids: Translated: 79; Mature: 79

Protein sequence:

>79_residues
MVKIVIHEERCHGCGNCVIACPVNACNSPNVWGGKGPEDGEDVVIKVVNGTVSVINEDLCEACMTCELACPVDAIEIKT

Sequences:

>Translated_79_residues
MVKIVIHEERCHGCGNCVIACPVNACNSPNVWGGKGPEDGEDVVIKVVNGTVSVINEDLCEACMTCELACPVDAIEIKT
>Mature_79_residues
MVKIVIHEERCHGCGNCVIACPVNACNSPNVWGGKGPEDGEDVVIKVVNGTVSVINEDLCEACMTCELACPVDAIEIKT

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile. May function as an electron transfer protein

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FWDG_METKA (Q49611)

Other databases:

- EMBL:   X98917
- EMBL:   AE009439
- RefSeq:   NP_614808.1
- ProteinModelPortal:   Q49611
- SMR:   Q49611
- GeneID:   1478120
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1525
- NMPDR:   fig|190192.1.peg.1521
- HOGENOM:   HBG734156
- OMA:   IVIHEER
- ProtClustDB:   CLSK876480
- BioCyc:   MKAN190192:MK1525-MONOMER
- BRENDA:   1.2.99.5
- GO:   GO:0015948
- GO:   GO:0006810
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900

Pfam domain/function: PF00037 Fer4

EC number: =1.2.99.5

Molecular weight: Translated: 8345; Mature: 8345

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

11.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
13.9 %Cys+Met (Translated Protein)
11.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
13.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIVIHEERCHGCGNCVIACPVNACNSPNVWGGKGPEDGEDVVIKVVNGTVSVINEDLC
CEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHH
EACMTCELACPVDAIEIKT
HHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MVKIVIHEERCHGCGNCVIACPVNACNSPNVWGGKGPEDGEDVVIKVVNGTVSVINEDLC
CEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHH
EACMTCELACPVDAIEIKT
HHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9076739; 11930014