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The map label for this gene is mat

Identifier: 20094944

GI number: 20094944

Start: 1523389

End: 1524582

Strand: Direct

Name: mat

Synonym: MK1508

Alternate gene names: 20094944

Gene position: 1523389-1524582 (Clockwise)

Preceding gene: 20094943

Following gene: 20094946

Centisome position: 89.88

GC content: 59.46

Gene sequence:

>1194_bases
ATGGTTAGAAACATTGTCGTCGAGACCATGAAACGCAGTCCTTTCACCGAAACCGAAGTGGAGATCGTCGAGCGAAAGGG
TGTAGGACACCCGGACAGTCTCGCCGACGGTATCGCGGAGAGCGTATCTAGGGCTCTGTGTCGGGAGTACATCGAGCGAT
TCGGCCGGATTCTACACCACAACACCGACGAGGTTCAAATCGTGGCGGGTGAATCGAGACCGGAGTTCGGAGGTGGAGAG
GTAATCCGGCCTATTTACATCCTGGTAACCGGACGCGCCACGGCGTACGTAGGGGACGAGGAGATCCCCGTCGGCACCAT
CGCGCTAGAAGCCGCGACGGAGTACTTGGAGGAGACCGTCAGACACCTAGATACCGAAAAGCACGTGGTAATCGAGCCGA
AGATCGGTCACGGTTCGGCGGATCTGCGGGACGTGTTCGAGCGCGGTGAGGAAGTTCCACTGGCGAACGACACCTCCTTC
GGCGTAGGGTACGCACCACTGACTACCACTGAGAGACTCGTGTACGAGACTGAGCGGAAGATCAACTCCCCGAAGCTCAA
GAAGGATCTACCGGAGGTCGGAGAAGACGTCAAGGTCATGGCACTTCGAGAGGATAACAAGATCGAACTAACCGTGGCCG
CTGCGATGGTGTCGCAGCGCATCGACGATATCGACCATTACATCTCCGTGGTCGAGGAGCTGAGAGACCGAGTCGCGGAC
TTAGCGGCCGAGATCGCCTCGGATCACGACGTCGAGGTGCACGTGAACACCGCCGACGACTACGAGCGGGAGTCCGTGTA
CCTGACGGTTACCGGCACATCAGCCGAACAGGGTGACGACGGTTCCGTCGGTCGTGGGAACCGCGTCAACGGTCTGATCA
CACCGTTCCGTCCGATGAGCATGGAAGCCGCCGCCGGAAAGAACCCCGTGAACCACGTCGGGAAACTCTACAACGTACTG
GCCCACCAGATGGCCCGGGAGATCTACGAGGAAACGTCAGCCGATGAGGTATACGTCCGGCTGCTCAGTCAGATCGGTCA
CCCCATCGACGATCCCAAGGCGGTCGACGTGCACCTCGTAGGGGACGTATCGGAGGAGGACGAGCGCGTGGCTCGACGCG
TGGCGGACGAGCTACTGGAGAACATCACCGAGCTCACGGAACGTATCGTGGAGGGCGAAATCGAGGTGTTCTGA

Upstream 100 bases:

>100_bases
ATAGTATTATCAGAATCCGGTAGGATCCGGCTGTACCACGGCGGGAAGGAGGTCCTGAAAATCTCGGTCTCAGACCTCGT
CGCTATTCGGGGGTTCTGCG

Downstream 100 bases:

>100_bases
AGCGACGCCTGTACCGAACTGAACACCGCCAAGTCACGCCTCGGCGACTCCGGCTACAGGCGATGATGTGGACCGTCCGC
GGGTTCGAATCCTCCCAGAA

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MVRNIVVETMKRSPFTETEVEIVERKGVGHPDSLADGIAESVSRALCREYIERFGRILHHNTDEVQIVAGESRPEFGGGE
VIRPIYILVTGRATAYVGDEEIPVGTIALEAATEYLEETVRHLDTEKHVVIEPKIGHGSADLRDVFERGEEVPLANDTSF
GVGYAPLTTTERLVYETERKINSPKLKKDLPEVGEDVKVMALREDNKIELTVAAAMVSQRIDDIDHYISVVEELRDRVAD
LAAEIASDHDVEVHVNTADDYERESVYLTVTGTSAEQGDDGSVGRGNRVNGLITPFRPMSMEAAAGKNPVNHVGKLYNVL
AHQMAREIYEETSADEVYVRLLSQIGHPIDDPKAVDVHLVGDVSEEDERVARRVADELLENITELTERIVEGEIEVF

Sequences:

>Translated_397_residues
MVRNIVVETMKRSPFTETEVEIVERKGVGHPDSLADGIAESVSRALCREYIERFGRILHHNTDEVQIVAGESRPEFGGGE
VIRPIYILVTGRATAYVGDEEIPVGTIALEAATEYLEETVRHLDTEKHVVIEPKIGHGSADLRDVFERGEEVPLANDTSF
GVGYAPLTTTERLVYETERKINSPKLKKDLPEVGEDVKVMALREDNKIELTVAAAMVSQRIDDIDHYISVVEELRDRVAD
LAAEIASDHDVEVHVNTADDYERESVYLTVTGTSAEQGDDGSVGRGNRVNGLITPFRPMSMEAAAGKNPVNHVGKLYNVL
AHQMAREIYEETSADEVYVRLLSQIGHPIDDPKAVDVHLVGDVSEEDERVARRVADELLENITELTERIVEGEIEVF
>Mature_397_residues
MVRNIVVETMKRSPFTETEVEIVERKGVGHPDSLADGIAESVSRALCREYIERFGRILHHNTDEVQIVAGESRPEFGGGE
VIRPIYILVTGRATAYVGDEEIPVGTIALEAATEYLEETVRHLDTEKHVVIEPKIGHGSADLRDVFERGEEVPLANDTSF
GVGYAPLTTTERLVYETERKINSPKLKKDLPEVGEDVKVMALREDNKIELTVAAAMVSQRIDDIDHYISVVEELRDRVAD
LAAEIASDHDVEVHVNTADDYERESVYLTVTGTSAEQGDDGSVGRGNRVNGLITPFRPMSMEAAAGKNPVNHVGKLYNVL
AHQMAREIYEETSADEVYVRLLSQIGHPIDDPKAVDVHLVGDVSEEDERVARRVADELLENITELTERIVEGEIEVF

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METK_METKA (Q8TV85)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614791.1
- ProteinModelPortal:   Q8TV85
- GeneID:   1478103
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1508
- NMPDR:   fig|190192.1.peg.1504
- HOGENOM:   HBG297280
- OMA:   RPMSMEA
- ProtClustDB:   PRK04439
- BioCyc:   MKAN190192:MK1508-MONOMER
- BRENDA:   2.5.1.6
- HAMAP:   MF_00136
- InterPro:   IPR002795
- ProDom:   PD011777

Pfam domain/function: PF01941 AdoMet_Synthase

EC number: =2.5.1.6

Molecular weight: Translated: 44076; Mature: 44076

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRNIVVETMKRSPFTETEVEIVERKGVGHPDSLADGIAESVSRALCREYIERFGRILHH
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NTDEVQIVAGESRPEFGGGEVIRPIYILVTGRATAYVGDEEIPVGTIALEAATEYLEETV
CCCCEEEEECCCCCCCCCCCEECEEEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHH
RHLDTEKHVVIEPKIGHGSADLRDVFERGEEVPLANDTSFGVGYAPLTTTERLVYETERK
HHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
INSPKLKKDLPEVGEDVKVMALREDNKIELTVAAAMVSQRIDDIDHYISVVEELRDRVAD
CCCCHHHHHHHHHCCCEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAEIASDHDVEVHVNTADDYERESVYLTVTGTSAEQGDDGSVGRGNRVNGLITPFRPMS
HHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCC
MEAAAGKNPVNHVGKLYNVLAHQMAREIYEETSADEVYVRLLSQIGHPIDDPKAVDVHLV
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEE
GDVSEEDERVARRVADELLENITELTERIVEGEIEVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVRNIVVETMKRSPFTETEVEIVERKGVGHPDSLADGIAESVSRALCREYIERFGRILHH
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NTDEVQIVAGESRPEFGGGEVIRPIYILVTGRATAYVGDEEIPVGTIALEAATEYLEETV
CCCCEEEEECCCCCCCCCCCEECEEEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHH
RHLDTEKHVVIEPKIGHGSADLRDVFERGEEVPLANDTSFGVGYAPLTTTERLVYETERK
HHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
INSPKLKKDLPEVGEDVKVMALREDNKIELTVAAAMVSQRIDDIDHYISVVEELRDRVAD
CCCCHHHHHHHHHCCCEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAEIASDHDVEVHVNTADDYERESVYLTVTGTSAEQGDDGSVGRGNRVNGLITPFRPMS
HHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCC
MEAAAGKNPVNHVGKLYNVLAHQMAREIYEETSADEVYVRLLSQIGHPIDDPKAVDVHLV
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEE
GDVSEEDERVARRVADELLENITELTERIVEGEIEVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014