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The map label for this gene is HypE_1

Identifier: 20094929

GI number: 20094929

Start: 1511580

End: 1512938

Strand: Reverse

Name: HypE_1

Synonym: MK1493

Alternate gene names: NA

Gene position: 1512938-1511580 (Counterclockwise)

Preceding gene: 20094931

Following gene: 20094923

Centisome position: 89.26

GC content: 64.02

Gene sequence:

>1359_bases
ATGGACCTAGAGGGATTATCCTTGCACATGCTGGAGGCTGGCGCATCCGAGGATGAGATTCGGGAGCTACTCACCGATCT
GGTGAAGATCTGGAAGCGGGACTGGTCGGAAGATGAGATCCGCGAGTTCGTCGACGCCGTTCTGGAGGAAGTACACCACG
TCCGGAAGGCTCACTTCCTCGGAGGGAGAGTCGGGGACATCCTTCGCCCGCCCGAATCGGGCGTGGGCATGGGCGAAATG
GGAGTGGGATCACGGGGTGAGGGAGACTTCTTCGTCCACGAGCTGCTTACTAGGCTCGCCGCTAAGGCCTCGGAAGGCGC
GCTAGTATCGCCCGAGGAGCGCGACGATGCGGGTGCCGTTCGTATAGACCCGGACGAGGTGATCCTCGTGAGTGCCGTGG
ACGGTATGCACTCGAGGCTCAGTGAGTTCCCCTTTCTCGCCGGCTTCCACGCGACCCGAGCCGCCATGCGGGACGTCCTC
GTGAACGGGGCACGTCCTCGTGGTCTCCTCGTCGATCTGCATCTAGCCGACGACGGAGATGTAGGTCGTCTTTTCGACTT
CACAGCGGGTGTGACCGCGGTGGGCGCGGCGACCGGCGTACCGATACTCGCGGGTAGCACCCTGCGCGTGGGAGGAGACA
TGGTGCTAGGGCGACGCCTGGTCGCGGGTGTAGCCTGCGTCGGTACCGCGCGGCCGGACGAGCTCACACCGCGGAGAGAT
GCCGAGCCGGGTGATCTGATCGTGCTCACCGAGGGCGCGGGCGGCGGTACGATCTCCACGACAGCGATCTACCACGGGTA
CTACGACGTGGTTGAGGAGACCCTCAACGTGGACTTCGTCCGGGCGGTTGAGGCGCTCCGGGAGGAGAACCTGCTCTCCG
AGGTTCACGCCATGACTGACATCACGAACGGGGGTATCCGGGGGGACGCGACGGAGATCTCCGAGACCGCGGGCGTCCGC
TTGGTTTTCGACGAGGAAACCGTGCGCTCCCTCGTCAACGATCGCGTCCTCCGGATGCTCGACGAACTCGACATCGATTA
CCTCGGGCTATCCCTGGACATGCTCATGGTGATCGCACCGGAAGACGTGGCCGAACGGTGCGTGGAAGCCCTCAACGGCG
TCGGGGTGCGGGCGGACGTCGTTGGTCGCGTTGAGGAGGGCTCCGGCGTCGTCCTCGAACGGGACGGAGAGGAAGTCGAG
CTGGACGTGAAGTTCCGGGAAACCGCGTACACTAAGGTGAAACGTGTCATCGGGGAGGAGCATCCCGAGGAGTTCGAAGA
AATGAAGGAGCGGGTCAGGCGAGCGTACGAGGAGGCCGAACGGAAGCTGCGGTGGGTACTCGAGCGGCTCGGGGAATGA

Upstream 100 bases:

>100_bases
CTCGTGCGTAACGTCGTGTTCCACTCACGACGGTCGAACGGGCGCTGAGAATCGGGTCTATAAGCTTCAGGGCGCTCGGC
GCCCTACGGGGGGTACTCCC

Downstream 100 bases:

>100_bases
CCGTGGTGAGGCCGTTATGTCAGCGGGTTTGCTCTCGGATCCACTCCAAGAACCCCTCGAATCCACCCAATACGGGTAAG
ACCAGTACCGCGGGCGTTTC

Product: hydrogenase maturation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MDLEGLSLHMLEAGASEDEIRELLTDLVKIWKRDWSEDEIREFVDAVLEEVHHVRKAHFLGGRVGDILRPPESGVGMGEM
GVGSRGEGDFFVHELLTRLAAKASEGALVSPEERDDAGAVRIDPDEVILVSAVDGMHSRLSEFPFLAGFHATRAAMRDVL
VNGARPRGLLVDLHLADDGDVGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARPDELTPRRD
AEPGDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVRAVEALREENLLSEVHAMTDITNGGIRGDATEISETAGVR
LVFDEETVRSLVNDRVLRMLDELDIDYLGLSLDMLMVIAPEDVAERCVEALNGVGVRADVVGRVEEGSGVVLERDGEEVE
LDVKFRETAYTKVKRVIGEEHPEEFEEMKERVRRAYEEAERKLRWVLERLGE

Sequences:

>Translated_452_residues
MDLEGLSLHMLEAGASEDEIRELLTDLVKIWKRDWSEDEIREFVDAVLEEVHHVRKAHFLGGRVGDILRPPESGVGMGEM
GVGSRGEGDFFVHELLTRLAAKASEGALVSPEERDDAGAVRIDPDEVILVSAVDGMHSRLSEFPFLAGFHATRAAMRDVL
VNGARPRGLLVDLHLADDGDVGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARPDELTPRRD
AEPGDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVRAVEALREENLLSEVHAMTDITNGGIRGDATEISETAGVR
LVFDEETVRSLVNDRVLRMLDELDIDYLGLSLDMLMVIAPEDVAERCVEALNGVGVRADVVGRVEEGSGVVLERDGEEVE
LDVKFRETAYTKVKRVIGEEHPEEFEEMKERVRRAYEEAERKLRWVLERLGE
>Mature_452_residues
MDLEGLSLHMLEAGASEDEIRELLTDLVKIWKRDWSEDEIREFVDAVLEEVHHVRKAHFLGGRVGDILRPPESGVGMGEM
GVGSRGEGDFFVHELLTRLAAKASEGALVSPEERDDAGAVRIDPDEVILVSAVDGMHSRLSEFPFLAGFHATRAAMRDVL
VNGARPRGLLVDLHLADDGDVGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARPDELTPRRD
AEPGDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVRAVEALREENLLSEVHAMTDITNGGIRGDATEISETAGVR
LVFDEETVRSLVNDRVLRMLDELDIDYLGLSLDMLMVIAPEDVAERCVEALNGVGVRADVVGRVEEGSGVVLERDGEEVE
LDVKFRETAYTKVKRVIGEEHPEEFEEMKERVRRAYEEAERKLRWVLERLGE

Specific function: Unknown

COG id: COG1973

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR009186
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 49419; Mature: 49419

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00398 RECOMBINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEGLSLHMLEAGASEDEIRELLTDLVKIWKRDWSEDEIREFVDAVLEEVHHVRKAHFL
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GGRVGDILRPPESGVGMGEMGVGSRGEGDFFVHELLTRLAAKASEGALVSPEERDDAGAV
CCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
RIDPDEVILVSAVDGMHSRLSEFPFLAGFHATRAAMRDVLVNGARPRGLLVDLHLADDGD
EECCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
VGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARPDELTPRRD
CCHHHHHHCCHHHHHHHCCCCEEECCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AEPGDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVRAVEALREENLLSEVHAMTD
CCCCCEEEEECCCCCCCEEHHHEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
ITNGGIRGDATEISETAGVRLVFDEETVRSLVNDRVLRMLDELDIDYLGLSLDMLMVIAP
CCCCCCCCCHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEEECC
EDVAERCVEALNGVGVRADVVGRVEEGSGVVLERDGEEVELDVKFRETAYTKVKRVIGEE
HHHHHHHHHHHHCCCCEEHHEEEEECCCCEEEECCCCEEEEEEEEHHHHHHHHHHHHCCC
HPEEFEEMKERVRRAYEEAERKLRWVLERLGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLEGLSLHMLEAGASEDEIRELLTDLVKIWKRDWSEDEIREFVDAVLEEVHHVRKAHFL
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GGRVGDILRPPESGVGMGEMGVGSRGEGDFFVHELLTRLAAKASEGALVSPEERDDAGAV
CCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
RIDPDEVILVSAVDGMHSRLSEFPFLAGFHATRAAMRDVLVNGARPRGLLVDLHLADDGD
EECCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
VGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARPDELTPRRD
CCHHHHHHCCHHHHHHHCCCCEEECCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AEPGDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVRAVEALREENLLSEVHAMTD
CCCCCEEEEECCCCCCCEEHHHEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
ITNGGIRGDATEISETAGVRLVFDEETVRSLVNDRVLRMLDELDIDYLGLSLDMLMVIAP
CCCCCCCCCHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEEECC
EDVAERCVEALNGVGVRADVVGRVEEGSGVVLERDGEEVELDVKFRETAYTKVKRVIGEE
HHHHHHHHHHHHCCCCEEHHEEEEECCCCEEEECCCCEEEEEEEEHHHHHHHHHHHHCCC
HPEEFEEMKERVRRAYEEAERKLRWVLERLGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]