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The map label for this gene is MraY [C]

Identifier: 20094190

GI number: 20094190

Start: 713877

End: 714947

Strand: Reverse

Name: MraY [C]

Synonym: MK0753

Alternate gene names: 20094190

Gene position: 714947-713877 (Counterclockwise)

Preceding gene: 20094191

Following gene: 20094189

Centisome position: 42.18

GC content: 58.08

Gene sequence:

>1071_bases
ATGATCATCGAGACGTTTACACTCTCCACAGTAACCTCGGCCGTAACGGTTGGATTACTCCGCAAGTACATGCGGGAAGC
TAACGTGGTAGACCGCCCGATCGTAACGGAACACGCGCATAAGTCCGGCATGCCCATCATGGGAGGTCTGGGGATCTTAC
TGGGAACGGCGTCCGGCCCCCTCCTAGCTTCCATCCAGGCGCTCCCTCCTATAGCTTCAGCGCTCCCCATGATGGTGCTA
GGAATAGTGGACGACCTGCTCGGATTGCAGGTGGAAGAGTTCCAGAAGGTCGTACGGAACGTCTCGAATCGACCGATCGA
GCTGGGAAGACTCATACTACAACCGGGCGAGGAGGCACGTGTAGCCACGGAGAAAGCGAAACGTGATCTGAAGAGGATAC
TCGAAGAGGACCCGGATGCCATCGAGATCGTCGGTGAGGTGCCTATCAAGAAAGAATTGAGTGAACGTGAGAAACTCGCA
CTACAGACTGGCGCCGCCCTCTTCGTTCTTCCTATCGTCCCCGCCACATGGCTCTGGATACCCAAGGTCGGCGTTTGGAA
CCTCTCGTACCTTTTCTATCCGGTCGCGGTGTTCGGAATTGTCGGCGCTACCAACGCCGTGAACCTCATCGACGGGATGG
ACGGTCTGGCCGCCGGGCTGCTGTTCCTGGCCTCACTGGCTTGCTCCGGCGTATGCCTGGGACAGGGCCAGCTTCCGGGT
GCTGCCTTCTTCGCATCACTTGCCGGAGCGTCCCTGGGTTTCCTGTTCCATAACAGATACCCGGCTAAGATCTTCATGGG
AGACACGGGGAGTTGCTTCTTAGGGGCGGCTTACGCGGCAGGAGCACTATATTACAAGATCGAGATACCTGCTATGATCG
CCTTAGGAGTCCCAGTACTGTCCACGCTCATCAGCTTGCTTCACCGAGCCGGCGTGATCCGGTTGGCTGTGGAACCTCTC
CACCACCATATCCAGTACAAGTACGACCTACCCGAACCCGTGGTTGTGGCGCTCCATTGGACCGCCGGAGCGGTGTTCGC
CGCCGTGGCACTCTGGATCTCCGTGGGGTGA

Upstream 100 bases:

>100_bases
GCGCTCAAGGCTGCAGGAGCGGACGTGAAGCGGGCCGAACGTGAGTATCGACGGAGGCTGAGGGAAATCGAGGAGTACTT
ATGACCGTGGGGAGCGGACG

Downstream 100 bases:

>100_bases
GGGGCGCTGCTGAAGCTCACGGTGAGGGAGCTGGCTGAGAATGTGGAAGGGGAAATACGCTCAGGCGACCCGGATAGTAT
GATCGCCGGATGGTTCTCCA

Product: UDP-N-acetylmuramyl pentapeptide phosphotransferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MIIETFTLSTVTSAVTVGLLRKYMREANVVDRPIVTEHAHKSGMPIMGGLGILLGTASGPLLASIQALPPIASALPMMVL
GIVDDLLGLQVEEFQKVVRNVSNRPIELGRLILQPGEEARVATEKAKRDLKRILEEDPDAIEIVGEVPIKKELSEREKLA
LQTGAALFVLPIVPATWLWIPKVGVWNLSYLFYPVAVFGIVGATNAVNLIDGMDGLAAGLLFLASLACSGVCLGQGQLPG
AAFFASLAGASLGFLFHNRYPAKIFMGDTGSCFLGAAYAAGALYYKIEIPAMIALGVPVLSTLISLLHRAGVIRLAVEPL
HHHIQYKYDLPEPVVVALHWTAGAVFAAVALWISVG

Sequences:

>Translated_356_residues
MIIETFTLSTVTSAVTVGLLRKYMREANVVDRPIVTEHAHKSGMPIMGGLGILLGTASGPLLASIQALPPIASALPMMVL
GIVDDLLGLQVEEFQKVVRNVSNRPIELGRLILQPGEEARVATEKAKRDLKRILEEDPDAIEIVGEVPIKKELSEREKLA
LQTGAALFVLPIVPATWLWIPKVGVWNLSYLFYPVAVFGIVGATNAVNLIDGMDGLAAGLLFLASLACSGVCLGQGQLPG
AAFFASLAGASLGFLFHNRYPAKIFMGDTGSCFLGAAYAAGALYYKIEIPAMIALGVPVLSTLISLLHRAGVIRLAVEPL
HHHIQYKYDLPEPVVVALHWTAGAVFAAVALWISVG
>Mature_356_residues
MIIETFTLSTVTSAVTVGLLRKYMREANVVDRPIVTEHAHKSGMPIMGGLGILLGTASGPLLASIQALPPIASALPMMVL
GIVDDLLGLQVEEFQKVVRNVSNRPIELGRLILQPGEEARVATEKAKRDLKRILEEDPDAIEIVGEVPIKKELSEREKLA
LQTGAALFVLPIVPATWLWIPKVGVWNLSYLFYPVAVFGIVGATNAVNLIDGMDGLAAGLLFLASLACSGVCLGQGQLPG
AAFFASLAGASLGFLFHNRYPAKIFMGDTGSCFLGAAYAAGALYYKIEIPAMIALGVPVLSTLISLLHRAGVIRLAVEPL
HHHIQYKYDLPEPVVVALHWTAGAVFAAVALWISVG

Specific function: First Step Of The Lipid Cycle Reactions In The Biosynthesis Of The Cell Wall Peptidoglycan. [C]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=330, Percent_Identity=28.4848484848485, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 37959; Mature: 37959

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIETFTLSTVTSAVTVGLLRKYMREANVVDRPIVTEHAHKSGMPIMGGLGILLGTASGP
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHEECCCCC
LLASIQALPPIASALPMMVLGIVDDLLGLQVEEFQKVVRNVSNRPIELGRLILQPGEEAR
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHH
VATEKAKRDLKRILEEDPDAIEIVGEVPIKKELSEREKLALQTGAALFVLPIVPATWLWI
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHEE
PKVGVWNLSYLFYPVAVFGIVGATNAVNLIDGMDGLAAGLLFLASLACSGVCLGQGQLPG
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHCCEEECCCCCCH
AAFFASLAGASLGFLFHNRYPAKIFMGDTGSCFLGAAYAAGALYYKIEIPAMIALGVPVL
HHHHHHHHCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCEEEEEEECCHHHHHHHHHH
STLISLLHRAGVIRLAVEPLHHHIQYKYDLPEPVVVALHWTAGAVFAAVALWISVG
HHHHHHHHHCCCCEEHHHHHHHHEEEEECCCCCEEEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIETFTLSTVTSAVTVGLLRKYMREANVVDRPIVTEHAHKSGMPIMGGLGILLGTASGP
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHEECCCCC
LLASIQALPPIASALPMMVLGIVDDLLGLQVEEFQKVVRNVSNRPIELGRLILQPGEEAR
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHH
VATEKAKRDLKRILEEDPDAIEIVGEVPIKKELSEREKLALQTGAALFVLPIVPATWLWI
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHEE
PKVGVWNLSYLFYPVAVFGIVGATNAVNLIDGMDGLAAGLLFLASLACSGVCLGQGQLPG
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHCCEEECCCCCCH
AAFFASLAGASLGFLFHNRYPAKIFMGDTGSCFLGAAYAAGALYYKIEIPAMIALGVPVL
HHHHHHHHCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCEEEEEEECCHHHHHHHHHH
STLISLLHRAGVIRLAVEPLHHHIQYKYDLPEPVVVALHWTAGAVFAAVALWISVG
HHHHHHHHHCCCCEEHHHHHHHHEEEEECCCCCEEEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]