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The map label for this gene is 20094059

Identifier: 20094059

GI number: 20094059

Start: 579226

End: 580800

Strand: Reverse

Name: 20094059

Synonym: MK0621

Alternate gene names: NA

Gene position: 580800-579226 (Counterclockwise)

Preceding gene: 20094060

Following gene: 20094058

Centisome position: 34.27

GC content: 65.71

Gene sequence:

>1575_bases
ATGGAGAAGCTCCCGGGTAAGGCCCCCGCCTACGTGTGCCAGGAGTGCGAGCTCGTCACGCCGCTGCGTCGGTGTCCGGA
GTGTGGTGAAGGTACGGACCCGCTACGCGTGACCCCTCCGGCGGAGCTCCGACCGGTAGGCCCCGGCTACTTGGAGTTCA
TCCGTGAGGTTTTGGTGGAGGAGGGATTACCGGCCGATCTCGTGCGTGACGACGAGCTGCTCCTCGCGAATCGTGCGCCT
GATCTCGATTACCTGGACGAGATCGTCGCCGCCGAGCCGGTACTGGCGCTGCGGTACGACTTACGGAAGGACCGTTGGAC
GATCGTGCTCAAGCCGGAGGGGGCGCGGCGTCTCCACGAGTTGGGCGGGAAATCGATCGAGGTGGACCGTGGGGCCGCGG
AGGCGGTGAGGGAGGGGAAGAACCTGTTCGCGCCGGGCGTGACGTCCGCGGACGACGTCGAGCCCGGTGAGTGGGTGGTG
ATCGAACACGGGGGTCGCCCGGTGGCCTTCGGTCGGGCCAGGATGTCGGGGGACGAAATGGTCCGCCGGAACCGCGGACT
GGCCGTGGAGGTGAGAGGTGCCGTAGAGGGGTCTCCAACGTACTTCCGCGGCAGGGACTTCGAGGACGTGGCGCGGGCGC
ACGAGGAGTACGTTTCGGAACGGCTGGAGGAGGCGGTGACGTTCGCCCGGGAGAACGTGAGCCCGTCCCGGACCTTCGCC
TCCTTCTCGGGCGGCAAGGACAGTCTGGTCACCTTAGTGGTGGCCGCGGAGGCGGGGGTGGAGCGCGCGCTCTTCGTGGA
CACGGGTATGGAGTTGCCGGAGACCGTGGAGGCAGCGGACCGGGCCGCCGAGGCCGTGGGTATCGACGTGGAAATAGTCG
AAGGGGACCCGGAGATATTCCACCGGGTGACGGAAGCTCTACTACCTCCTTCTCGAGATAACAGGTGGTGCACGCTGGCC
GCGAAGCTCACCCCTGTTACGAGGTACGTTCGCTCCGAGTTCGGCCGAGGGTGTTACACGCTGGTGGGCGTCCGAAGGTA
CGAGTCCGAGGCCCGATCCGAGCGGGGTAGGGTGTGGGACAGCGACGCGGTGCCGGGACAGGTGAACGTGGCCCCTATCT
TCGATTGGTCGTCCCTGGACGTCTGGTTGTGCGTGCACTCCAAGGATTTACCGTACAACCCGCTTTACGATGAGGGGTTC
GACAGAATAGGGTGTTACATGTGCCCGGCGAGCAAAGTCGGGGACTTCAGGCTATCGGAGCGCGTACATCCCGAACTTTG
GGAGGGGTGGATGGAAACGCTCGAGCGATACCGCGAGAGGCACGGGTTGCCGCGCGATTGGCTCCGGTATCACGTTTGGA
GGTGGTTACGTCCCGAGGGCGAGATCCGGAAGGTCGCCAGCGAGGAGTCGCTACGGTGGGGAGAGCGCGTTCTCGGGCGG
TGGCGGGAGGTTCCCCCGGAGGAGGCGGCTCGAGGTTTCCGTCGGGAGTGTCCAGGTTGTGGGTACTGCGGTGCGGTAGG
GTCGAATCGGTGCGAGATATTGGAAGCCAGCCTGCGGCGGGTGTTCGGTCGATGA

Upstream 100 bases:

>100_bases
ACGTGGCGCGGGAGGATCGAGCGGGCCCTGCGCGCGACCGAGGCGGCGGTCAACCGGCTGGGCGTGGAGGGGTTCGCGGA
GGTCTACCGGGGGTACTGGG

Downstream 100 bases:

>100_bases
AGGTTAGGGATCGAGCGTTGGAGATAATCAGGGAGAGGATCTCGCGGGGCGACCCACTCTACGACTTCACCGGGTTGGCG
TCGCGACCGAAGGTCGACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MEKLPGKAPAYVCQECELVTPLRRCPECGEGTDPLRVTPPAELRPVGPGYLEFIREVLVEEGLPADLVRDDELLLANRAP
DLDYLDEIVAAEPVLALRYDLRKDRWTIVLKPEGARRLHELGGKSIEVDRGAAEAVREGKNLFAPGVTSADDVEPGEWVV
IEHGGRPVAFGRARMSGDEMVRRNRGLAVEVRGAVEGSPTYFRGRDFEDVARAHEEYVSERLEEAVTFARENVSPSRTFA
SFSGGKDSLVTLVVAAEAGVERALFVDTGMELPETVEAADRAAEAVGIDVEIVEGDPEIFHRVTEALLPPSRDNRWCTLA
AKLTPVTRYVRSEFGRGCYTLVGVRRYESEARSERGRVWDSDAVPGQVNVAPIFDWSSLDVWLCVHSKDLPYNPLYDEGF
DRIGCYMCPASKVGDFRLSERVHPELWEGWMETLERYRERHGLPRDWLRYHVWRWLRPEGEIRKVASEESLRWGERVLGR
WREVPPEEAARGFRRECPGCGYCGAVGSNRCEILEASLRRVFGR

Sequences:

>Translated_524_residues
MEKLPGKAPAYVCQECELVTPLRRCPECGEGTDPLRVTPPAELRPVGPGYLEFIREVLVEEGLPADLVRDDELLLANRAP
DLDYLDEIVAAEPVLALRYDLRKDRWTIVLKPEGARRLHELGGKSIEVDRGAAEAVREGKNLFAPGVTSADDVEPGEWVV
IEHGGRPVAFGRARMSGDEMVRRNRGLAVEVRGAVEGSPTYFRGRDFEDVARAHEEYVSERLEEAVTFARENVSPSRTFA
SFSGGKDSLVTLVVAAEAGVERALFVDTGMELPETVEAADRAAEAVGIDVEIVEGDPEIFHRVTEALLPPSRDNRWCTLA
AKLTPVTRYVRSEFGRGCYTLVGVRRYESEARSERGRVWDSDAVPGQVNVAPIFDWSSLDVWLCVHSKDLPYNPLYDEGF
DRIGCYMCPASKVGDFRLSERVHPELWEGWMETLERYRERHGLPRDWLRYHVWRWLRPEGEIRKVASEESLRWGERVLGR
WREVPPEEAARGFRRECPGCGYCGAVGSNRCEILEASLRRVFGR
>Mature_524_residues
MEKLPGKAPAYVCQECELVTPLRRCPECGEGTDPLRVTPPAELRPVGPGYLEFIREVLVEEGLPADLVRDDELLLANRAP
DLDYLDEIVAAEPVLALRYDLRKDRWTIVLKPEGARRLHELGGKSIEVDRGAAEAVREGKNLFAPGVTSADDVEPGEWVV
IEHGGRPVAFGRARMSGDEMVRRNRGLAVEVRGAVEGSPTYFRGRDFEDVARAHEEYVSERLEEAVTFARENVSPSRTFA
SFSGGKDSLVTLVVAAEAGVERALFVDTGMELPETVEAADRAAEAVGIDVEIVEGDPEIFHRVTEALLPPSRDNRWCTLA
AKLTPVTRYVRSEFGRGCYTLVGVRRYESEARSERGRVWDSDAVPGQVNVAPIFDWSSLDVWLCVHSKDLPYNPLYDEGF
DRIGCYMCPASKVGDFRLSERVHPELWEGWMETLERYRERHGLPRDWLRYHVWRWLRPEGEIRKVASEESLRWGERVLGR
WREVPPEEAARGFRRECPGCGYCGAVGSNRCEILEASLRRVFGR

Specific function: Unknown

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002500
- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR004521 [H]

Pfam domain/function: PF01507 PAPS_reduct; PF01472 PUA [H]

EC number: NA

Molecular weight: Translated: 59067; Mature: 59067

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLPGKAPAYVCQECELVTPLRRCPECGEGTDPLRVTPPAELRPVGPGYLEFIREVLVE
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
EGLPADLVRDDELLLANRAPDLDYLDEIVAAEPVLALRYDLRKDRWTIVLKPEGARRLHE
CCCCHHHCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCHHHHHHH
LGGKSIEVDRGAAEAVREGKNLFAPGVTSADDVEPGEWVVIEHGGRPVAFGRARMSGDEM
CCCCEEEECCCHHHHHHCCCCEECCCCCCCCCCCCCCEEEEECCCCEEEECHHHCCHHHH
VRRNRGLAVEVRGAVEGSPTYFRGRDFEDVARAHEEYVSERLEEAVTFARENVSPSRTFA
HHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
SFSGGKDSLVTLVVAAEAGVERALFVDTGMELPETVEAADRAAEAVGIDVEIVEGDPEIF
HCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHH
HRVTEALLPPSRDNRWCTLAAKLTPVTRYVRSEFGRGCYTLVGVRRYESEARSERGRVWD
HHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
SDAVPGQVNVAPIFDWSSLDVWLCVHSKDLPYNPLYDEGFDRIGCYMCPASKVGDFRLSE
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHC
RVHPELWEGWMETLERYRERHGLPRDWLRYHVWRWLRPEGEIRKVASEESLRWGERVLGR
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WREVPPEEAARGFRRECPGCGYCGAVGSNRCEILEASLRRVFGR
HHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKLPGKAPAYVCQECELVTPLRRCPECGEGTDPLRVTPPAELRPVGPGYLEFIREVLVE
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
EGLPADLVRDDELLLANRAPDLDYLDEIVAAEPVLALRYDLRKDRWTIVLKPEGARRLHE
CCCCHHHCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCHHHHHHH
LGGKSIEVDRGAAEAVREGKNLFAPGVTSADDVEPGEWVVIEHGGRPVAFGRARMSGDEM
CCCCEEEECCCHHHHHHCCCCEECCCCCCCCCCCCCCEEEEECCCCEEEECHHHCCHHHH
VRRNRGLAVEVRGAVEGSPTYFRGRDFEDVARAHEEYVSERLEEAVTFARENVSPSRTFA
HHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
SFSGGKDSLVTLVVAAEAGVERALFVDTGMELPETVEAADRAAEAVGIDVEIVEGDPEIF
HCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHH
HRVTEALLPPSRDNRWCTLAAKLTPVTRYVRSEFGRGCYTLVGVRRYESEARSERGRVWD
HHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
SDAVPGQVNVAPIFDWSSLDVWLCVHSKDLPYNPLYDEGFDRIGCYMCPASKVGDFRLSE
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHC
RVHPELWEGWMETLERYRERHGLPRDWLRYHVWRWLRPEGEIRKVASEESLRWGERVLGR
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WREVPPEEAARGFRRECPGCGYCGAVGSNRCEILEASLRRVFGR
HHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]