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The map label for this gene is SelA

Identifier: 20094058

GI number: 20094058

Start: 578231

End: 579271

Strand: Reverse

Name: SelA

Synonym: MK0620

Alternate gene names: NA

Gene position: 579271-578231 (Counterclockwise)

Preceding gene: 20094059

Following gene: 20094057

Centisome position: 34.18

GC content: 62.73

Gene sequence:

>1041_bases
GTGCGAGATATTGGAAGCCAGCCTGCGGCGGGTGTTCGGTCGATGAAGGTTAGGGATCGAGCGTTGGAGATAATCAGGGA
GAGGATCTCGCGGGGCGACCCACTCTACGACTTCACCGGGTTGGCGTCGCGACCGAAGGTCGACGCTGCCTCGGACGAGC
TCCGTACCTATCTGTCGGAAGCGCTGATTTTGCCGGAGATCCGGGAGCTCTGTCGGGAGCACTTCGACGCTCCGGAGTAC
GAGGTACTGGTGGCCCCTAGGACGACGGCGGCCGTTATCGCGACGATCCTGGCCCTCGAGCCGAGGAGTGTGTTGCACGT
ACTACCCGAGGACGGTGAAGCCCACCCATGCGTGGAGGAAGGCTGCAGGTTGGCGGGGGCGGAGTACGAGGAGGTCGAGG
AGTCGGAGATACCCGATCTCGACGGGTTCGATCTCGTGGTCGTAACGGGTTGCGACGTGCGTTGGAACGTGGTAAGCGAG
GACACTCTGAGGGAGGTCGCCTCCGCGGAGGCCGTGACGCTGCTGGACGACGCTTCGGGCGACCGAGTACGTCGATTGCA
CGGCCAAAAGCCGGGTCCGAGGTACGGGTTCGACCTAGTGGTAACGAGCTGCGACAAGCTGATGGACGGGCCACGCGCCG
GCGTGCTGATCGGACGGGACGACCTCGTGGAGGGCGTGCGGCGGGTCTGCGAAGGATACGGTTGGACGGTCGATGGACCG
ACGCTCGCGGCCGTAAAAAGGGCCTTTGAAGAGTTCGAGTTGAGCTCACTGGAAGCTCGGTTAAAGGAACTTGAACGCGT
GTACGAGCGGCTCAAGGACGAGCTCGACGTGGAACGGACGGGTGCGGGTCTGGTGTTCCACGGGGTGGAACGGGAGGTGG
AGATAGGGCTCGGGTTGCTGCGACGGTACGGGATTATGACCATAACCGCCCTGGGTTACGAGCGTGTGGATAGAACCTTG
CGCTTCAATCTTCTGACGGAGGACGCGGAGCGGTTCGGTTACGATCGGTTCGTCGAGGTCGTGAAGGGGGAGCTGTCATG
A

Upstream 100 bases:

>100_bases
TTCTCGGGCGGTGGCGGGAGGTTCCCCCGGAGGAGGCGGCTCGAGGTTTCCGTCGGGAGTGTCCAGGTTGTGGGTACTGC
GGTGCGGTAGGGTCGAATCG

Downstream 100 bases:

>100_bases
CCGGGACGATGATCGAGGAGTACCTGGCGGCGCCGATCGTGGAGGCCGTGATATTGGGGTTGGCCTGCTACGTGGTGGTG
CGCAAGGGTCTGCCCGCGCT

Product: selenocysteine synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRDIGSQPAAGVRSMKVRDRALEIIRERISRGDPLYDFTGLASRPKVDAASDELRTYLSEALILPEIRELCREHFDAPEY
EVLVAPRTTAAVIATILALEPRSVLHVLPEDGEAHPCVEEGCRLAGAEYEEVEESEIPDLDGFDLVVVTGCDVRWNVVSE
DTLREVASAEAVTLLDDASGDRVRRLHGQKPGPRYGFDLVVTSCDKLMDGPRAGVLIGRDDLVEGVRRVCEGYGWTVDGP
TLAAVKRAFEEFELSSLEARLKELERVYERLKDELDVERTGAGLVFHGVEREVEIGLGLLRRYGIMTITALGYERVDRTL
RFNLLTEDAERFGYDRFVEVVKGELS

Sequences:

>Translated_346_residues
MRDIGSQPAAGVRSMKVRDRALEIIRERISRGDPLYDFTGLASRPKVDAASDELRTYLSEALILPEIRELCREHFDAPEY
EVLVAPRTTAAVIATILALEPRSVLHVLPEDGEAHPCVEEGCRLAGAEYEEVEESEIPDLDGFDLVVVTGCDVRWNVVSE
DTLREVASAEAVTLLDDASGDRVRRLHGQKPGPRYGFDLVVTSCDKLMDGPRAGVLIGRDDLVEGVRRVCEGYGWTVDGP
TLAAVKRAFEEFELSSLEARLKELERVYERLKDELDVERTGAGLVFHGVEREVEIGLGLLRRYGIMTITALGYERVDRTL
RFNLLTEDAERFGYDRFVEVVKGELS
>Mature_346_residues
MRDIGSQPAAGVRSMKVRDRALEIIRERISRGDPLYDFTGLASRPKVDAASDELRTYLSEALILPEIRELCREHFDAPEY
EVLVAPRTTAAVIATILALEPRSVLHVLPEDGEAHPCVEEGCRLAGAEYEEVEESEIPDLDGFDLVVVTGCDVRWNVVSE
DTLREVASAEAVTLLDDASGDRVRRLHGQKPGPRYGFDLVVTSCDKLMDGPRAGVLIGRDDLVEGVRRVCEGYGWTVDGP
TLAAVKRAFEEFELSSLEARLKELERVYERLKDELDVERTGAGLVFHGVEREVEIGLGLLRRYGIMTITALGYERVDRTL
RFNLLTEDAERFGYDRFVEVVKGELS

Specific function: Unknown

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y620_METKA (Q8TXP1)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613905.1
- HSSP:   Q57622
- ProteinModelPortal:   Q8TXP1
- SMR:   Q8TXP1
- GeneID:   1476721
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0620
- NMPDR:   fig|190192.1.peg.618
- HOGENOM:   HBG540973
- OMA:   KFGLEAQ
- BioCyc:   MKAN190192:MK0620-MONOMER
- InterPro:   IPR020033
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- Gene3D:   G3DSA:3.40.640.10
- TIGRFAMs:   TIGR03576

Pfam domain/function: PF03841 SelA; SSF53383 PyrdxlP-dep_Trfase_major

EC number: NA

Molecular weight: Translated: 38637; Mature: 38637

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDIGSQPAAGVRSMKVRDRALEIIRERISRGDPLYDFTGLASRPKVDAASDELRTYLSE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALILPEIRELCREHFDAPEYEVLVAPRTTAAVIATILALEPRSVLHVLPEDGEAHPCVEE
HHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHEECCCCCCCCCCHHH
GCRLAGAEYEEVEESEIPDLDGFDLVVVTGCDVRWNVVSEDTLREVASAEAVTLLDDASG
HHHHCCCCHHHHHHHCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHCCCCEEEEECCCC
DRVRRLHGQKPGPRYGFDLVVTSCDKLMDGPRAGVLIGRDDLVEGVRRVCEGYGWTVDGP
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCH
TLAAVKRAFEEFELSSLEARLKELERVYERLKDELDVERTGAGLVFHGVEREVEIGLGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEECCCHHHHHHHHHH
RRYGIMTITALGYERVDRTLRFNLLTEDAERFGYDRFVEVVKGELS
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
>Mature Secondary Structure
MRDIGSQPAAGVRSMKVRDRALEIIRERISRGDPLYDFTGLASRPKVDAASDELRTYLSE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALILPEIRELCREHFDAPEYEVLVAPRTTAAVIATILALEPRSVLHVLPEDGEAHPCVEE
HHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHEECCCCCCCCCCHHH
GCRLAGAEYEEVEESEIPDLDGFDLVVVTGCDVRWNVVSEDTLREVASAEAVTLLDDASG
HHHHCCCCHHHHHHHCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHCCCCEEEEECCCC
DRVRRLHGQKPGPRYGFDLVVTSCDKLMDGPRAGVLIGRDDLVEGVRRVCEGYGWTVDGP
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCH
TLAAVKRAFEEFELSSLEARLKELERVYERLKDELDVERTGAGLVFHGVEREVEIGLGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEECCCHHHHHHHHHH
RRYGIMTITALGYERVDRTLRFNLLTEDAERFGYDRFVEVVKGELS
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014