Click here to switch to the map view.

The map label for this gene is SUA7_1 [H]

Identifier: 20094057

GI number: 20094057

Start: 576853

End: 577878

Strand: Reverse

Name: SUA7_1 [H]

Synonym: MK0619

Alternate gene names: 20094057

Gene position: 577878-576853 (Counterclockwise)

Preceding gene: 20094058

Following gene: 20094056

Centisome position: 34.09

GC content: 60.33

Gene sequence:

>1026_bases
ATGGTCTACACCGAGTCGGAGCATCGGGTGTGCCCGAAGTGTGGCAGCACGAACCTAGAGCGTGACGAGAAGCACGGGGA
ACTGGTCTGTCGGGACTGCGGCACCGTCGTCGACTATCTGATCGACTACGGGCCCGAGTGGAGGGCCTTCAACGCGGATC
AGCGCGCGCAGCGTGAGCGTACGGGTGCACCCATCTCGGAGCGTCATCCGCACAAGTTAGGGGACACGATCATCGATGAC
CGTGACACTCGCGGTCGGCGTCTCGTGGACTGGCGGTTCAGGCGTCTGAAGAGGTGGGATAGGTGGATTTCGAACGACCC
GGTCAGCAGGAACATCCGATCCGCCGTAGAACTTATTGAGAGGGTATGCTCGCAGGCTAACATCCCCCGGTCCATCGTGG
ATGAAGCGATCCGGATTTATCGGAAGGCCGTGGAGAAGGATCTAGTCCGAGGTAGGTCGATCGAGAACACGGCCGCGGCC
GCACTGTTCATGGCGTGTAAGAAGCGTAAGCACCCCCGTACTATCAAGGAGATTGCGAAACTGTTCGGGATCACGCCCAA
AGACATCAACCGAACGCATCGGGTCCTACTCCGGCACCTGAACGAGCGTATGCCCGCTCCGGATCCGAAGCAGTACCTGT
CCCGATTCGCGACCGAGCTGGGTGTCTCTGAAGATGTCGAAATGCTAGCCCGTGAGATCCTGGAGAAAGCCGAGAAGAAG
GGCCTGACCGTGAGCCGCAACCCGGCCGGACTGGCGGGCGCGGCCCTGTACCTGGCCGGGCTCCTCAAGGCTAAGGAGTA
CATAGAGGAGTACCGCGAGAAGATGAAGGAGGCCGAGTCGGAGGAAGAGAAGGAGAAGCTCGAACGTGAGCTCAACGAGA
AGCTCCGAACGTGCCGTCGGACACAGCCCGAGGTTGCGAAGATCTCGGGAGTTACCGAAGTCACGATCAGGAATCGGTAC
AAGGAGCTGGCCGAGGAGCTGGGCCTGGAAGTTCCGGACCCAACTAAGATCGACGTGCCGGCGTGA

Upstream 100 bases:

>100_bases
TCGCGGTGGGACTGTGCCCGCGCAGCGGGGAGTAATCTATTTAAAATCTTTCCCGAAAAGCCAACCGGGCCGTTTCCCGG
CGTAAGGGGGTGAGGCCGCC

Downstream 100 bases:

>100_bases
GACCCTCGAGGGAAACACAGAAACCACGGCGTTTCCGAAACTCGCGATCCGACCGTGGGACTACGATCGCGCGCTCTACC
CCCACCATATACCAATCTCA

Product: transcription initiation factor IIB

Products: NA

Alternate protein names: TFIIB [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MVYTESEHRVCPKCGSTNLERDEKHGELVCRDCGTVVDYLIDYGPEWRAFNADQRAQRERTGAPISERHPHKLGDTIIDD
RDTRGRRLVDWRFRRLKRWDRWISNDPVSRNIRSAVELIERVCSQANIPRSIVDEAIRIYRKAVEKDLVRGRSIENTAAA
ALFMACKKRKHPRTIKEIAKLFGITPKDINRTHRVLLRHLNERMPAPDPKQYLSRFATELGVSEDVEMLAREILEKAEKK
GLTVSRNPAGLAGAALYLAGLLKAKEYIEEYREKMKEAESEEEKEKLERELNEKLRTCRRTQPEVAKISGVTEVTIRNRY
KELAEELGLEVPDPTKIDVPA

Sequences:

>Translated_341_residues
MVYTESEHRVCPKCGSTNLERDEKHGELVCRDCGTVVDYLIDYGPEWRAFNADQRAQRERTGAPISERHPHKLGDTIIDD
RDTRGRRLVDWRFRRLKRWDRWISNDPVSRNIRSAVELIERVCSQANIPRSIVDEAIRIYRKAVEKDLVRGRSIENTAAA
ALFMACKKRKHPRTIKEIAKLFGITPKDINRTHRVLLRHLNERMPAPDPKQYLSRFATELGVSEDVEMLAREILEKAEKK
GLTVSRNPAGLAGAALYLAGLLKAKEYIEEYREKMKEAESEEEKEKLERELNEKLRTCRRTQPEVAKISGVTEVTIRNRY
KELAEELGLEVPDPTKIDVPA
>Mature_341_residues
MVYTESEHRVCPKCGSTNLERDEKHGELVCRDCGTVVDYLIDYGPEWRAFNADQRAQRERTGAPISERHPHKLGDTIIDD
RDTRGRRLVDWRFRRLKRWDRWISNDPVSRNIRSAVELIERVCSQANIPRSIVDEAIRIYRKAVEKDLVRGRSIENTAAA
ALFMACKKRKHPRTIKEIAKLFGITPKDINRTHRVLLRHLNERMPAPDPKQYLSRFATELGVSEDVEMLAREILEKAEKK
GLTVSRNPAGLAGAALYLAGLLKAKEYIEEYREKMKEAESEEEKEKLERELNEKLRTCRRTQPEVAKISGVTEVTIRNRY
KELAEELGLEVPDPTKIDVPA

Specific function: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) [H]

COG id: COG1405

COG function: function code K; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TFIIB-type zinc finger [H]

Homologues:

Organism=Homo sapiens, GI4504193, Length=342, Percent_Identity=28.0701754385965, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI22035556, Length=275, Percent_Identity=25.0909090909091, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564892, Length=315, Percent_Identity=28.8888888888889, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17531397, Length=255, Percent_Identity=22.3529411764706, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6325343, Length=275, Percent_Identity=23.6363636363636, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321685, Length=325, Percent_Identity=22.4615384615385, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17136758, Length=326, Percent_Identity=27.3006134969325, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281361961, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647658, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006670
- InterPro:   IPR011028
- InterPro:   IPR013763
- InterPro:   IPR000812
- InterPro:   IPR013150
- InterPro:   IPR013137 [H]

Pfam domain/function: PF00382 TFIIB; PF08271 TFIIB_Zn_Ribbon [H]

EC number: NA

Molecular weight: Translated: 39424; Mature: 39424

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS51134 ZF_TFIIB ; PS00782 TFIIB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYTESEHRVCPKCGSTNLERDEKHGELVCRDCGTVVDYLIDYGPEWRAFNADQRAQRER
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TGAPISERHPHKLGDTIIDDRDTRGRRLVDWRFRRLKRWDRWISNDPVSRNIRSAVELIE
CCCCCCCCCCHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RVCSQANIPRSIVDEAIRIYRKAVEKDLVRGRSIENTAAAALFMACKKRKHPRTIKEIAK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
LFGITPKDINRTHRVLLRHLNERMPAPDPKQYLSRFATELGVSEDVEMLAREILEKAEKK
HHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GLTVSRNPAGLAGAALYLAGLLKAKEYIEEYREKMKEAESEEEKEKLERELNEKLRTCRR
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TQPEVAKISGVTEVTIRNRYKELAEELGLEVPDPTKIDVPA
CCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVYTESEHRVCPKCGSTNLERDEKHGELVCRDCGTVVDYLIDYGPEWRAFNADQRAQRER
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TGAPISERHPHKLGDTIIDDRDTRGRRLVDWRFRRLKRWDRWISNDPVSRNIRSAVELIE
CCCCCCCCCCHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RVCSQANIPRSIVDEAIRIYRKAVEKDLVRGRSIENTAAAALFMACKKRKHPRTIKEIAK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
LFGITPKDINRTHRVLLRHLNERMPAPDPKQYLSRFATELGVSEDVEMLAREILEKAEKK
HHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GLTVSRNPAGLAGAALYLAGLLKAKEYIEEYREKMKEAESEEEKEKLERELNEKLRTCRR
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TQPEVAKISGVTEVTIRNRYKELAEELGLEVPDPTKIDVPA
CCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]