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The map label for this gene is GapA

Identifier: 20094056

GI number: 20094056

Start: 575280

End: 576332

Strand: Reverse

Name: GapA

Synonym: MK0618

Alternate gene names: 20094056

Gene position: 576332-575280 (Counterclockwise)

Preceding gene: 20094057

Following gene: 20094055

Centisome position: 34.0

GC content: 61.92

Gene sequence:

>1053_bases
TTGGCCGACGTTAGCGTGTTGATCAACGGGTACGGAACCATCGGTAAGAGAGTCGCCGATGCCGTCGACGCTCAGCGTGA
CATGGAAGTACTCGGAGTGGTCAAAACGTCGCCGGATTACCTGGCCCGGTTGGCCGTCGAGGAGTACGGTTACCCGCTGT
TCGTGCCGGAAGACCGCGTTGAGAGGTTCGAAGATGCAGGAATCGAGACCGAGGGTACCGTGGAAGACGTGGTGCTGAAC
GCCGAGGACTACGGGTTGGACGTCGTCGTGGACTGCACCCCCGAAGGCATCGGAGCCCGGAACAAAGAGACGCTATACGA
GAAAGCCGGGGTTAAGGCGATCTTCCAAGGTGGCGAGGAGGCGGAAGTCGCCGAGGTGTCGTTCGTCGCCCAATGTAACT
ACGAGGAGGCCCTGGGGGCTGACTACGTCCGGTGTGTGTCGTGCAACACCACGGCCCTGTGCCGCACGCTAGGGACGCTG
AAGGAGGAGTTCGAGCTCGGGCGTGTCTACGTGACGATCGTACGTCGGGCGGCCGACCCGCACCAGGTGAAGAAGGGACC
TATCAACGCCATCGCGCCGAACCCGGTGACGGTGCCGTCCCACCACGGACCGGATGTTAAGACCGTGATGCCGGACATCG
ACATTACGACAGCGGCCGTGAAGGTGCCGACGACGCTCATGCACATGCACGTTGTCAGGGTGGAGCTGAAGGAAGAGGTC
ACGTCGGACGACGTCATCGACGCGTTCGAGGAGGCGAGAAGGATATGGGTGGTACCGCACGGGGAGGGGCTCGGTTCCAC
GGCCGAGTTAATCGAGTTGGGACGTGACCTCGGTAGGAAGCGGTACGACCTGTACGAGATACTGGTTTGGGAAGAGTCCA
TCAACGTGGAGGACGGCGTGCTCTACTACATGCAGGCCGTGCACCAGGAGGCCGACGTCGTACCCGAGAACGTGGACGCT
ATCCGCGCGATGACCGAGTTGGAGGAGGATCCGGAGGCCTCCATGGACGCCACGGACAGCGCACTCGGCGTGCTCAACTC
CCCGCCACTATAA

Upstream 100 bases:

>100_bases
GCGGGAGGTACATTTCCACCGCCTTATTATCCATCACGCGGGATCCGAACGGCGCTAATTTAAGCTCCGAGTTACGGGCA
GCGCGCGGGGGAGGCGGGTC

Downstream 100 bases:

>100_bases
CGCCCTTTCCGCCCCGGCTTGAAGCAACCTTATTATTCCCCGAACGACGAGGGGGTGCTGGGAAACCGAGTTCGCGCTCA
TCCTTCACTCCTCATGGTCG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH; NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MADVSVLINGYGTIGKRVADAVDAQRDMEVLGVVKTSPDYLARLAVEEYGYPLFVPEDRVERFEDAGIETEGTVEDVVLN
AEDYGLDVVVDCTPEGIGARNKETLYEKAGVKAIFQGGEEAEVAEVSFVAQCNYEEALGADYVRCVSCNTTALCRTLGTL
KEEFELGRVYVTIVRRAADPHQVKKGPINAIAPNPVTVPSHHGPDVKTVMPDIDITTAAVKVPTTLMHMHVVRVELKEEV
TSDDVIDAFEEARRIWVVPHGEGLGSTAELIELGRDLGRKRYDLYEILVWEESINVEDGVLYYMQAVHQEADVVPENVDA
IRAMTELEEDPEASMDATDSALGVLNSPPL

Sequences:

>Translated_350_residues
MADVSVLINGYGTIGKRVADAVDAQRDMEVLGVVKTSPDYLARLAVEEYGYPLFVPEDRVERFEDAGIETEGTVEDVVLN
AEDYGLDVVVDCTPEGIGARNKETLYEKAGVKAIFQGGEEAEVAEVSFVAQCNYEEALGADYVRCVSCNTTALCRTLGTL
KEEFELGRVYVTIVRRAADPHQVKKGPINAIAPNPVTVPSHHGPDVKTVMPDIDITTAAVKVPTTLMHMHVVRVELKEEV
TSDDVIDAFEEARRIWVVPHGEGLGSTAELIELGRDLGRKRYDLYEILVWEESINVEDGVLYYMQAVHQEADVVPENVDA
IRAMTELEEDPEASMDATDSALGVLNSPPL
>Mature_349_residues
ADVSVLINGYGTIGKRVADAVDAQRDMEVLGVVKTSPDYLARLAVEEYGYPLFVPEDRVERFEDAGIETEGTVEDVVLNA
EDYGLDVVVDCTPEGIGARNKETLYEKAGVKAIFQGGEEAEVAEVSFVAQCNYEEALGADYVRCVSCNTTALCRTLGTLK
EEFELGRVYVTIVRRAADPHQVKKGPINAIAPNPVTVPSHHGPDVKTVMPDIDITTAAVKVPTTLMHMHVVRVELKEEVT
SDDVIDAFEEARRIWVVPHGEGLGSTAELIELGRDLGRKRYDLYEILVWEESINVEDGVLYYMQAVHQEADVVPENVDAI
RAMTELEEDPEASMDATDSALGVLNSPPL

Specific function: Unknown

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G3P_METKA (P58839)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613903.1
- ProteinModelPortal:   P58839
- SMR:   P58839
- GeneID:   1476719
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0618
- NMPDR:   fig|190192.1.peg.616
- HOGENOM:   HBG392099
- OMA:   HHGPDVQ
- ProtClustDB:   PRK04207
- BioCyc:   MKAN190192:MK0618-MONOMER
- BRENDA:   1.2.1.59
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00559
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006436
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000149
- SMART:   SM00846
- TIGRFAMs:   TIGR01546

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.59

Molecular weight: Translated: 38368; Mature: 38236

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00071 GAPDH

Important sites: ACT_SITE 148-148 BINDING 118-118 BINDING 176-176 BINDING 309-309

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVSVLINGYGTIGKRVADAVDAQRDMEVLGVVKTSPDYLARLAVEEYGYPLFVPEDRV
CCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCEEECCHHHH
ERFEDAGIETEGTVEDVVLNAEDYGLDVVVDCTPEGIGARNKETLYEKAGVKAIFQGGEE
HHHHHCCCCCCCCHHHEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCHHHHCCCCC
AEVAEVSFVAQCNYEEALGADYVRCVSCNTTALCRTLGTLKEEFELGRVYVTIVRRAADP
CHHHHEEEEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCH
HQVKKGPINAIAPNPVTVPSHHGPDVKTVMPDIDITTAAVKVPTTLMHMHVVRVELKEEV
HHHCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHC
TSDDVIDAFEEARRIWVVPHGEGLGSTAELIELGRDLGRKRYDLYEILVWEESINVEDGV
CCCHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHCEEEEEEEECCCCCCCHH
LYYMQAVHQEADVVPENVDAIRAMTELEEDPEASMDATDSALGVLNSPPL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
ADVSVLINGYGTIGKRVADAVDAQRDMEVLGVVKTSPDYLARLAVEEYGYPLFVPEDRV
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCEEECCHHHH
ERFEDAGIETEGTVEDVVLNAEDYGLDVVVDCTPEGIGARNKETLYEKAGVKAIFQGGEE
HHHHHCCCCCCCCHHHEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCHHHHCCCCC
AEVAEVSFVAQCNYEEALGADYVRCVSCNTTALCRTLGTLKEEFELGRVYVTIVRRAADP
CHHHHEEEEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCH
HQVKKGPINAIAPNPVTVPSHHGPDVKTVMPDIDITTAAVKVPTTLMHMHVVRVELKEEV
HHHCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHC
TSDDVIDAFEEARRIWVVPHGEGLGSTAELIELGRDLGRKRYDLYEILVWEESINVEDGV
CCCHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHCEEEEEEEECCCCCCCHH
LYYMQAVHQEADVVPENVDAIRAMTELEEDPEASMDATDSALGVLNSPPL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014