Click here to switch to the map view.

The map label for this gene is HdrC

Identifier: 20094011

GI number: 20094011

Start: 534381

End: 534959

Strand: Reverse

Name: HdrC

Synonym: MK0573

Alternate gene names: 20094011

Gene position: 534959-534381 (Counterclockwise)

Preceding gene: 20094013

Following gene: 20094010

Centisome position: 31.56

GC content: 57.86

Gene sequence:

>579_bases
TTGGTCGAGCCACGAGATACCGTCATCCGTGAGGAGGATCTCAACCCGGACTTCCTAGAAGAACTGAGCGAGCTCGTCGA
GCCCGTGTTCGAGGAGGAAGAGGTACTGTCGGTCCAGGCGTGCTACCAGTGCGGTACATGCACGGGCTCGTGCCCCAGCG
GACGACGAACCTCCTACCGCACCCGACTGATCATGCGGAAGCTCCAGTTAGGACTCGTCGACGAAGTGATCAAGAGCGAC
GAGCTGTGGATGTGCACCACATGCTACACGTGCTACGAACGCTGCCCACGTGGTGTGAAGATCGTAGACGCCGTTAAAGC
CGCCCGGAACCTCGCGGCCAAGAAGGGGTACATGGCCAAGGCTCACAGGATGGTGGCTATGTTCGTGATAAAGACCGGGC
ACGCCGTACCGATCAACGATGAGATCCGCGAGGTGAGGAAGAACATCGGCCTCGACGAAGTACCACCGACGACACATCGG
TATGAGGAAGCTCTCGAAGAGGTCCAGAAGCTGGTCAAGATCAACGAGTTCGACAAACTGATCGGGTACGATTGGGAGGA
GGGTGATCTGGTCGACTAA

Upstream 100 bases:

>100_bases
GGAGCCGTTCCCCGCAGGTTGACGTTGAGCGTACCTACACGCGGTGCCGGGTGGGTATCGTAAAAAGGTTCTTCTGGGCG
GAACCCTTCAGGGCCGCGCG

Downstream 100 bases:

>100_bases
GGGGGTTGACCCTTGGCCAAGAAGCTCTGCTTCTTCCTTGGTTGTATCATGCCGAACAGGTATCCGGGCATCGAGAAGGC
CACGCGTTTAGTCTTCGAGG

Product: heterodisulfide reductase, subunit C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MVEPRDTVIREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTSYRTRLIMRKLQLGLVDEVIKSD
ELWMCTTCYTCYERCPRGVKIVDAVKAARNLAAKKGYMAKAHRMVAMFVIKTGHAVPINDEIREVRKNIGLDEVPPTTHR
YEEALEEVQKLVKINEFDKLIGYDWEEGDLVD

Sequences:

>Translated_192_residues
MVEPRDTVIREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTSYRTRLIMRKLQLGLVDEVIKSD
ELWMCTTCYTCYERCPRGVKIVDAVKAARNLAAKKGYMAKAHRMVAMFVIKTGHAVPINDEIREVRKNIGLDEVPPTTHR
YEEALEEVQKLVKINEFDKLIGYDWEEGDLVD
>Mature_192_residues
MVEPRDTVIREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTSYRTRLIMRKLQLGLVDEVIKSD
ELWMCTTCYTCYERCPRGVKIVDAVKAARNLAAKKGYMAKAHRMVAMFVIKTGHAVPINDEIREVRKNIGLDEVPPTTHR
YEEALEEVQKLVKINEFDKLIGYDWEEGDLVD

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B)

COG id: COG1150

COG function: function code C; Heterodisulfide reductase, subunit C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDRC_METKA (Q8TXT7)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613858.1
- ProteinModelPortal:   Q8TXT7
- GeneID:   1476674
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0573
- NMPDR:   fig|190192.1.peg.571
- HOGENOM:   HBG542047
- OMA:   KTGHAVP
- BioCyc:   MKAN190192:MK0573-MONOMER
- BRENDA:   1.8.98.1
- GO:   GO:0015948
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017680
- InterPro:   IPR012285
- InterPro:   IPR009051
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR03290

Pfam domain/function: SSF46548 Helical_ferredxn

EC number: =1.8.98.1

Molecular weight: Translated: 22023; Mature: 22023

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPRDTVIREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTSYR
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
TRLIMRKLQLGLVDEVIKSDELWMCTTCYTCYERCPRGVKIVDAVKAARNLAAKKGYMAK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AHRMVAMFVIKTGHAVPINDEIREVRKNIGLDEVPPTTHRYEEALEEVQKLVKINEFDKL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IGYDWEEGDLVD
HCCCCCCCCCCC
>Mature Secondary Structure
MVEPRDTVIREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTSYR
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
TRLIMRKLQLGLVDEVIKSDELWMCTTCYTCYERCPRGVKIVDAVKAARNLAAKKGYMAK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AHRMVAMFVIKTGHAVPINDEIREVRKNIGLDEVPPTTHRYEEALEEVQKLVKINEFDKL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IGYDWEEGDLVD
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014