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The map label for this gene is HdrB

Identifier: 20094010

GI number: 20094010

Start: 533451

End: 534368

Strand: Reverse

Name: HdrB

Synonym: MK0572

Alternate gene names: 20094010

Gene position: 534368-533451 (Counterclockwise)

Preceding gene: 20094011

Following gene: 20094008

Centisome position: 31.53

GC content: 58.93

Gene sequence:

>918_bases
TTGGCCAAGAAGCTCTGCTTCTTCCTTGGTTGTATCATGCCGAACAGGTATCCGGGCATCGAGAAGGCCACGCGTTTAGT
CTTCGAGGAACTAGGATACGAGCTCGTCGACATGGACGGTGCCTCCTGCTGTCCGGCGCCCGGAGTGTTCGGGTCCTTCG
ACCTCAAGACGTGGGTTACGATCGCAGCCCGCAACCTGTCGATAGCCGAGGAGAAAGGATACGACATTCTGACGGTCTGT
AACGGTTGCTTCGGATCCCTGAACGAAGCCAACCACCTGTTGCAGGAGAACCCGGAACTGCGCGAGTTCGTGAACGAAAA
GCTCGCCGAGATCGACAGGGAGTACAAGGGTAAGGTCAAGGTCTACCACGTGAACACCTTCCTTTACGAGGAGGTAGGTG
TCAAAAAGATCAAGGAGAAGGTCGAGAGGCCGCTCGAGAAGACCGACGGTGAGCCGCTGAAGGTAGCGGTTCACTACGGT
TGCCACCTGCTGAAGCCGTCGGAGGTGACCGGGTTCCCAGGTTCGGTCGAGGACCCGAGGACGCTCGACGAGCTCGTCGA
GGCCCTAGGGGCGGAGTCCGTCGACTACAAGGACAAGATCATGTGCTGCGGTGCGGGAGGTGGTGTGAGGTCCAGGGAAC
TCAAGGTGTCACTTCACTTCACCCGCGAGAAGATCTTCAACATGCTCGAAGCCGGTGCCGACTGCACTACCAACGTCTGT
CCGTTCTGCCACCTACAGTTCGACCGTGGACAGATCGAGATGAAGGAGCACTTCGAGAAGCTCCCACCGAAGAAGCTACC
GGTGTTCCACTACTGCCAGCTGGCCGGTCTGGCGTTCGGAATGGACCCGGAGGAGCTCGCCCTCGAGACGCACGAGATCG
ACTGCACGCCCGTACTCGAGAAGCTCGGCCTCGCCTGA

Upstream 100 bases:

>100_bases
TCTCGAAGAGGTCCAGAAGCTGGTCAAGATCAACGAGTTCGACAAACTGATCGGGTACGATTGGGAGGAGGGTGATCTGG
TCGACTAAGGGGGTTGACCC

Downstream 100 bases:

>100_bases
TTTTTTTCACTCCAACCCGAGCTTTCTCCTGTAATACCGGTTCGTGAGGGCTAAGGCTGGACAGTGGGCCAGCCTCCGGT
CCTTCACCACCGCGACGGTC

Product: heterodisulfide reductase, subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAKKLCFFLGCIMPNRYPGIEKATRLVFEELGYELVDMDGASCCPAPGVFGSFDLKTWVTIAARNLSIAEEKGYDILTVC
NGCFGSLNEANHLLQENPELREFVNEKLAEIDREYKGKVKVYHVNTFLYEEVGVKKIKEKVERPLEKTDGEPLKVAVHYG
CHLLKPSEVTGFPGSVEDPRTLDELVEALGAESVDYKDKIMCCGAGGGVRSRELKVSLHFTREKIFNMLEAGADCTTNVC
PFCHLQFDRGQIEMKEHFEKLPPKKLPVFHYCQLAGLAFGMDPEELALETHEIDCTPVLEKLGLA

Sequences:

>Translated_305_residues
MAKKLCFFLGCIMPNRYPGIEKATRLVFEELGYELVDMDGASCCPAPGVFGSFDLKTWVTIAARNLSIAEEKGYDILTVC
NGCFGSLNEANHLLQENPELREFVNEKLAEIDREYKGKVKVYHVNTFLYEEVGVKKIKEKVERPLEKTDGEPLKVAVHYG
CHLLKPSEVTGFPGSVEDPRTLDELVEALGAESVDYKDKIMCCGAGGGVRSRELKVSLHFTREKIFNMLEAGADCTTNVC
PFCHLQFDRGQIEMKEHFEKLPPKKLPVFHYCQLAGLAFGMDPEELALETHEIDCTPVLEKLGLA
>Mature_304_residues
AKKLCFFLGCIMPNRYPGIEKATRLVFEELGYELVDMDGASCCPAPGVFGSFDLKTWVTIAARNLSIAEEKGYDILTVCN
GCFGSLNEANHLLQENPELREFVNEKLAEIDREYKGKVKVYHVNTFLYEEVGVKKIKEKVERPLEKTDGEPLKVAVHYGC
HLLKPSEVTGFPGSVEDPRTLDELVEALGAESVDYKDKIMCCGAGGGVRSRELKVSLHFTREKIFNMLEAGADCTTNVCP
FCHLQFDRGQIEMKEHFEKLPPKKLPVFHYCQLAGLAFGMDPEELALETHEIDCTPVLEKLGLA

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDRB_METKA (Q8TXT8)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613857.1
- GeneID:   1476673
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0572
- NMPDR:   fig|190192.1.peg.570
- HOGENOM:   HBG513215
- OMA:   HYGCHFL
- ProtClustDB:   CLSK876313
- BioCyc:   MKAN190192:MK0572-MONOMER
- BRENDA:   1.8.98.1
- GO:   GO:0015948
- InterPro:   IPR017678
- InterPro:   IPR004017
- TIGRFAMs:   TIGR03288

Pfam domain/function: PF02754 CCG

EC number: =1.8.98.1

Molecular weight: Translated: 34132; Mature: 34001

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKLCFFLGCIMPNRYPGIEKATRLVFEELGYELVDMDGASCCPAPGVFGSFDLKTWVT
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHH
IAARNLSIAEEKGYDILTVCNGCFGSLNEANHLLQENPELREFVNEKLAEIDREYKGKVK
HHHCCCEEHHHCCCEEEEEHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
VYHVNTFLYEEVGVKKIKEKVERPLEKTDGEPLKVAVHYGCHLLKPSEVTGFPGSVEDPR
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCCCCCCCCH
TLDELVEALGAESVDYKDKIMCCGAGGGVRSRELKVSLHFTREKIFNMLEAGADCTTNVC
HHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCC
PFCHLQFDRGQIEMKEHFEKLPPKKLPVFHYCQLAGLAFGMDPEELALETHEIDCTPVLE
CEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
KLGLA
HHCCC
>Mature Secondary Structure 
AKKLCFFLGCIMPNRYPGIEKATRLVFEELGYELVDMDGASCCPAPGVFGSFDLKTWVT
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHH
IAARNLSIAEEKGYDILTVCNGCFGSLNEANHLLQENPELREFVNEKLAEIDREYKGKVK
HHHCCCEEHHHCCCEEEEEHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
VYHVNTFLYEEVGVKKIKEKVERPLEKTDGEPLKVAVHYGCHLLKPSEVTGFPGSVEDPR
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCCCCCCCCH
TLDELVEALGAESVDYKDKIMCCGAGGGVRSRELKVSLHFTREKIFNMLEAGADCTTNVC
HHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCC
PFCHLQFDRGQIEMKEHFEKLPPKKLPVFHYCQLAGLAFGMDPEELALETHEIDCTPVLE
CEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
KLGLA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014