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The map label for this gene is SurE

Identifier: 20093871

GI number: 20093871

Start: 404865

End: 405650

Strand: Reverse

Name: SurE

Synonym: MK0433

Alternate gene names: 20093871

Gene position: 405650-404865 (Counterclockwise)

Preceding gene: 20093872

Following gene: 20093870

Centisome position: 23.93

GC content: 59.29

Gene sequence:

>786_bases
GTGAGAATACTGATCACCAACGACGACGGCATAGCCTCTCCCGGTCTCCGAGCGGCCGTCCGCGCCTGCAGGAGTGTCGG
TGAAGTTACCGTAGTAGCTCCCGCGACGCAGCAAAGTGGTGTAGGGCGCAGTATCTCTTTACTCGAGCCAGTGCGGGTGG
AAGAGATAGAGGTAGAAGGCGTCGACGCGCTCGCGATCTCCGGTACGCCGGCGGACGCCGTCCTCATCGGAGCGTTCTCT
ATCATGGATGAGCCACCCGATTTGGTGGTCTCGGGGATCAACCTCGGAGAGAACGTCAGCGCTGACGTCACGACCTCGGG
GACCGTCGGCGCAGCGCTGGAAGCTTACGGGAACGGCATTCCGGCCATAGCGATCTCGCAAGAGGTCCGTGACGCCAGAG
CACGCGTGGACAACAACGCCAAGAACGTCGACTTCACCTTGGCCATCAGAGTCTTGAAGGCCCTGCTCGAAGCGATTCGA
GGGGCGAATTGGGAAGGTGTCTTGAACGTCAACGTGCCGGATCCGGATCGCTGGAACGGCGAAATTAAAGTGGTTCCATT
AGCTTTCACGATGTACCGGCCCAGAATAGAAAAACGATACGATCCGCGTGGGCGTCGATACTACTGGATCGACGGCGAGA
TTATCCAAGATCCGCCCGAGGGAACCGACCTGTACGAACTCCAGCGGGGCTCCATAGTAATCACACCTCTGACGACCGAC
GTCACCGGAGACTTGGACGCTGCGGAAAACGTTATCAAGGAGCTCCGGCGTGCCCTGCGGGGATAA

Upstream 100 bases:

>100_bases
CGGACGGCCGGAGGCTGCCTGCGCGTGTCGCTTTCCGACGGACCGCTGCTGATAGGGAGGGCTGAGATCGTGTACAAGGG
TGAACTGCGGGGTGATTGGC

Downstream 100 bases:

>100_bases
AGGTTGCTCGCGGAGGTCCTGCTGCAACCTATGGTCGTCTCCGTACTCATCGGCTCGACCGCGGCCGTGATAATAGTTCT
CATAGCCCTCAAAACTTACT

Product: acid phosphatase

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRILITNDDGIASPGLRAAVRACRSVGEVTVVAPATQQSGVGRSISLLEPVRVEEIEVEGVDALAISGTPADAVLIGAFS
IMDEPPDLVVSGINLGENVSADVTTSGTVGAALEAYGNGIPAIAISQEVRDARARVDNNAKNVDFTLAIRVLKALLEAIR
GANWEGVLNVNVPDPDRWNGEIKVVPLAFTMYRPRIEKRYDPRGRRYYWIDGEIIQDPPEGTDLYELQRGSIVITPLTTD
VTGDLDAAENVIKELRRALRG

Sequences:

>Translated_261_residues
MRILITNDDGIASPGLRAAVRACRSVGEVTVVAPATQQSGVGRSISLLEPVRVEEIEVEGVDALAISGTPADAVLIGAFS
IMDEPPDLVVSGINLGENVSADVTTSGTVGAALEAYGNGIPAIAISQEVRDARARVDNNAKNVDFTLAIRVLKALLEAIR
GANWEGVLNVNVPDPDRWNGEIKVVPLAFTMYRPRIEKRYDPRGRRYYWIDGEIIQDPPEGTDLYELQRGSIVITPLTTD
VTGDLDAAENVIKELRRALRG
>Mature_261_residues
MRILITNDDGIASPGLRAAVRACRSVGEVTVVAPATQQSGVGRSISLLEPVRVEEIEVEGVDALAISGTPADAVLIGAFS
IMDEPPDLVVSGINLGENVSADVTTSGTVGAALEAYGNGIPAIAISQEVRDARARVDNNAKNVDFTLAIRVLKALLEAIR
GANWEGVLNVNVPDPDRWNGEIKVVPLAFTMYRPRIEKRYDPRGRRYYWIDGEIIQDPPEGTDLYELQRGSIVITPLTTD
VTGDLDAAENVIKELRRALRG

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=260, Percent_Identity=36.1538461538462, Blast_Score=128, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319570, Length=251, Percent_Identity=30.2788844621514, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_METKA (Q8TY72)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613718.1
- ProteinModelPortal:   Q8TY72
- SMR:   Q8TY72
- GeneID:   1477736
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0433
- NMPDR:   fig|190192.1.peg.431
- HOGENOM:   HBG600532
- OMA:   SINVIYS
- BioCyc:   MKAN190192:MK0433-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28082; Mature: 28082

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILITNDDGIASPGLRAAVRACRSVGEVTVVAPATQQSGVGRSISLLEPVRVEEIEVEG
CEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECC
VDALAISGTPADAVLIGAFSIMDEPPDLVVSGINLGENVSADVTTSGTVGAALEAYGNGI
CEEEEECCCCCCEEEEEEHHHCCCCCCCEEECCCCCCCCCCCEECCCCHHHHHHHHCCCC
PAIAISQEVRDARARVDNNAKNVDFTLAIRVLKALLEAIRGANWEGVLNVNVPDPDRWNG
CEEEEHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
EIKVVPLAFTMYRPRIEKRYDPRGRRYYWIDGEIIQDPPEGTDLYELQRGSIVITPLTTD
EEEEEEEEEEECCCHHHHCCCCCCCEEEEECCEEECCCCCCCCCEEECCCCEEEEEECCC
VTGDLDAAENVIKELRRALRG
CCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRILITNDDGIASPGLRAAVRACRSVGEVTVVAPATQQSGVGRSISLLEPVRVEEIEVEG
CEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECC
VDALAISGTPADAVLIGAFSIMDEPPDLVVSGINLGENVSADVTTSGTVGAALEAYGNGI
CEEEEECCCCCCEEEEEEHHHCCCCCCCEEECCCCCCCCCCCEECCCCHHHHHHHHCCCC
PAIAISQEVRDARARVDNNAKNVDFTLAIRVLKALLEAIRGANWEGVLNVNVPDPDRWNG
CEEEEHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
EIKVVPLAFTMYRPRIEKRYDPRGRRYYWIDGEIIQDPPEGTDLYELQRGSIVITPLTTD
EEEEEEEEEEECCCHHHHCCCCCCCEEEEECCEEECCCCCCCCCEEECCCCEEEEEECCC
VTGDLDAAENVIKELRRALRG
CCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014