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The map label for this gene is comD [H]

Identifier: 20093833

GI number: 20093833

Start: 377707

End: 378210

Strand: Direct

Name: comD [H]

Synonym: MK0395

Alternate gene names: 20093833

Gene position: 377707-378210 (Clockwise)

Preceding gene: 20093832

Following gene: 20093840

Centisome position: 22.28

GC content: 59.33

Gene sequence:

>504_bases
TTGAACGTCGATGACGCCATCGTCGAGGCGCTAGAGGAGGCTGGAATCACCTTCGCCTGCTGGCTACCCTGTTCCCTCTT
GGACGGGATCATCAGGCGATTGGAAGAACACCCAGAGATCCGAACGGTCAGGGTGTCCAGGGAGGAAGAAGGCGTAGGGA
TCTGCGCGGGAGCTGCCCTCGCGGGCGAGAAACCCGCACTGATAATGCAGAACTCGGGTCTCGGTAACTCCGTCAACGCT
CTCTGCTCACTCACCTTAACCTACCGACTCCCACTGCTGATGTTGATGAGTCACCGTGGCTACCTGTTCGAAGACATCCC
GGCACAGGTGGGGATGGGGAAAGCGGCGCCTAAGATCTTGGAAAACCTCAATCTACACGCGTTCACGATCGAGCGGCCGG
AAGAGCTGGACGTGATACCGGGTGCCTGGAAGCTCGCCGAGACTGCGGGCGAACCCGTCGGTGTATTCTTAAGTCCGAGA
CTGTGGCGTCAGACGGGCCGATAG

Upstream 100 bases:

>100_bases
CGCGAACGTCCCGCCGGAGGAGGTGATACCGCTAGCCACACTGCGGGCGGGTCTCAGAGCGGAGACCATGGGCCGGGTCG
CGCTGGACGGGGAATGACGC

Downstream 100 bases:

>100_bases
AAGACGTGGAAGCAGTCCCAACTCTTCTCTACGATCACGTCATGCAGCTCTTCGAACGACGGCTCGTACAGTTCCACATC
GAGTCCGCGCCACCGGACCA

Product: thiamine-pyrophosphate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNVDDAIVEALEEAGITFACWLPCSLLDGIIRRLEEHPEIRTVRVSREEEGVGICAGAALAGEKPALIMQNSGLGNSVNA
LCSLTLTYRLPLLMLMSHRGYLFEDIPAQVGMGKAAPKILENLNLHAFTIERPEELDVIPGAWKLAETAGEPVGVFLSPR
LWRQTGR

Sequences:

>Translated_167_residues
MNVDDAIVEALEEAGITFACWLPCSLLDGIIRRLEEHPEIRTVRVSREEEGVGICAGAALAGEKPALIMQNSGLGNSVNA
LCSLTLTYRLPLLMLMSHRGYLFEDIPAQVGMGKAAPKILENLNLHAFTIERPEELDVIPGAWKLAETAGEPVGVFLSPR
LWRQTGR
>Mature_167_residues
MNVDDAIVEALEEAGITFACWLPCSLLDGIIRRLEEHPEIRTVRVSREEEGVGICAGAALAGEKPALIMQNSGLGNSVNA
LCSLTLTYRLPLLMLMSHRGYLFEDIPAQVGMGKAAPKILENLNLHAFTIERPEELDVIPGAWKLAETAGEPVGVFLSPR
LWRQTGR

Specific function: Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde [H]

COG id: COG4032

COG function: function code R; Predicted thiamine-pyrophosphate-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022502
- InterPro:   IPR012001 [H]

Pfam domain/function: PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.79 [H]

Molecular weight: Translated: 18233; Mature: 18233

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDDAIVEALEEAGITFACWLPCSLLDGIIRRLEEHPEIRTVRVSREEEGVGICAGAAL
CCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCC
AGEKPALIMQNSGLGNSVNALCSLTLTYRLPLLMLMSHRGYLFEDIPAQVGMGKAAPKIL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCCHHHHH
ENLNLHAFTIERPEELDVIPGAWKLAETAGEPVGVFLSPRLWRQTGR
HCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHCCC
>Mature Secondary Structure
MNVDDAIVEALEEAGITFACWLPCSLLDGIIRRLEEHPEIRTVRVSREEEGVGICAGAAL
CCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCC
AGEKPALIMQNSGLGNSVNALCSLTLTYRLPLLMLMSHRGYLFEDIPAQVGMGKAAPKIL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCCHHHHH
ENLNLHAFTIERPEELDVIPGAWKLAETAGEPVGVFLSPRLWRQTGR
HCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 10940029 [H]