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The map label for this gene is comA [H]

Identifier: 20093832

GI number: 20093832

Start: 376933

End: 377703

Strand: Direct

Name: comA [H]

Synonym: MK0394

Alternate gene names: 20093832

Gene position: 376933-377703 (Clockwise)

Preceding gene: 20093829

Following gene: 20093833

Centisome position: 22.24

GC content: 60.83

Gene sequence:

>771_bases
GTGAAGGCGTTCGAGAAGTCCGTGAAGATTCCCAAGGTGGACGGCGCGACGGTCATGCTGGACAAGGGATTGACACCCGA
GTTCGTGGAATCGTTCCTGAAAGTCGCCGGAGAGTACGTGACGGCCGTCAAGCTGGGATGGGGCACGGCCCGGCTCATCG
ACAAGGAGATCGTCGCGCGAAAGGTCGAGATGTACGTGGATGCGGGGCTGGACGTGTTCCCGGGAGGCACCCTGGCCGAG
ATAGCGATTGCTCAGGGTAACTTCGAGGGGTACTTGAACGAGCTCGATGAGCTGGGATTCAACGCGATCGAGATCTCAGA
CGGTATGATCCCAATGTCCATCGAGAAGAAGTGCGAGCTCATCGAGCGGGCGTGCGAGCAGGGTTTCACCGTCTACGCCG
AGGAAGGTAAGAAGAGAGACGAGGAGTACTCCGTGCTTTCGCCATCCGACATCGTGGGGCGCATGAACAAGTGCGTGGAG
GCCGGTGCCGAGTACGTGATCGTCGAGGCCAGAGAAAGCGGTAAGCACGGTCCGATGGGAGCGGAGAAGAGGGAGCGCGT
GCGCGTACTCTCGGAGATCGTTAAGGGAGTCGGGATTCAGCGCGTGATGTTCGAGGCTCCGGAGAAGGAGCAGCAGTTCG
AGCTGATCGTCAAGTTCGGTCCTGAGGTCAACATCGCGAACGTCCCGCCGGAGGAGGTGATACCGCTAGCCACACTGCGG
GCGGGTCTCAGAGCGGAGACCATGGGCCGGGTCGCGCTGGACGGGGAATGA

Upstream 100 bases:

>100_bases
TACTCTCAGAGCTTCAATTCGCTTCATGCCCATCGACCCCGCGTCGCCCGGTCCCGAATACACTAAAGCCGTTCCCCCCG
GATCGGCCGGAGGGCGCCCG

Downstream 100 bases:

>100_bases
CGCTTGAACGTCGATGACGCCATCGTCGAGGCGCTAGAGGAGGCTGGAATCACCTTCGCCTGCTGGCTACCCTGTTCCCT
CTTGGACGGGATCATCAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: (2R)-phospho-3-sulfolactate synthase; PSL synthase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKAFEKSVKIPKVDGATVMLDKGLTPEFVESFLKVAGEYVTAVKLGWGTARLIDKEIVARKVEMYVDAGLDVFPGGTLAE
IAIAQGNFEGYLNELDELGFNAIEISDGMIPMSIEKKCELIERACEQGFTVYAEEGKKRDEEYSVLSPSDIVGRMNKCVE
AGAEYVIVEARESGKHGPMGAEKRERVRVLSEIVKGVGIQRVMFEAPEKEQQFELIVKFGPEVNIANVPPEEVIPLATLR
AGLRAETMGRVALDGE

Sequences:

>Translated_256_residues
MKAFEKSVKIPKVDGATVMLDKGLTPEFVESFLKVAGEYVTAVKLGWGTARLIDKEIVARKVEMYVDAGLDVFPGGTLAE
IAIAQGNFEGYLNELDELGFNAIEISDGMIPMSIEKKCELIERACEQGFTVYAEEGKKRDEEYSVLSPSDIVGRMNKCVE
AGAEYVIVEARESGKHGPMGAEKRERVRVLSEIVKGVGIQRVMFEAPEKEQQFELIVKFGPEVNIANVPPEEVIPLATLR
AGLRAETMGRVALDGE
>Mature_256_residues
MKAFEKSVKIPKVDGATVMLDKGLTPEFVESFLKVAGEYVTAVKLGWGTARLIDKEIVARKVEMYVDAGLDVFPGGTLAE
IAIAQGNFEGYLNELDELGFNAIEISDGMIPMSIEKKCELIERACEQGFTVYAEEGKKRDEEYSVLSPSDIVGRMNKCVE
AGAEYVIVEARESGKHGPMGAEKRERVRVLSEIVKGVGIQRVMFEAPEKEQQFELIVKFGPEVNIANVPPEEVIPLATLR
AGLRAETMGRVALDGE

Specific function: Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) [H]

COG id: COG1809

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphosulfolactate synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022370
- InterPro:   IPR003830 [H]

Pfam domain/function: PF02679 ComA [H]

EC number: =4.4.1.19 [H]

Molecular weight: Translated: 28103; Mature: 28103

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFEKSVKIPKVDGATVMLDKGLTPEFVESFLKVAGEYVTAVKLGWGTARLIDKEIVAR
CCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
KVEMYVDAGLDVFPGGTLAEIAIAQGNFEGYLNELDELGFNAIEISDGMIPMSIEKKCEL
HHHHHHHCCCEECCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
IERACEQGFTVYAEEGKKRDEEYSVLSPSDIVGRMNKCVEAGAEYVIVEARESGKHGPMG
HHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
AEKRERVRVLSEIVKGVGIQRVMFEAPEKEQQFELIVKFGPEVNIANVPPEEVIPLATLR
CHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHEEEEEECCCEEECCCCHHHHHHHHHHH
AGLRAETMGRVALDGE
HCCCHHHCCCEEECCC
>Mature Secondary Structure
MKAFEKSVKIPKVDGATVMLDKGLTPEFVESFLKVAGEYVTAVKLGWGTARLIDKEIVAR
CCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
KVEMYVDAGLDVFPGGTLAEIAIAQGNFEGYLNELDELGFNAIEISDGMIPMSIEKKCEL
HHHHHHHCCCEECCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
IERACEQGFTVYAEEGKKRDEEYSVLSPSDIVGRMNKCVEAGAEYVIVEARESGKHGPMG
HHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
AEKRERVRVLSEIVKGVGIQRVMFEAPEKEQQFELIVKFGPEVNIANVPPEEVIPLATLR
CHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHEEEEEECCCEEECCCCHHHHHHHHHHH
AGLRAETMGRVALDGE
HCCCHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]