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The map label for this gene is MurG [H]

Identifier: 20093810

GI number: 20093810

Start: 361116

End: 362186

Strand: Reverse

Name: MurG [H]

Synonym: MK0372

Alternate gene names: 20093810

Gene position: 362186-361116 (Counterclockwise)

Preceding gene: 20093813

Following gene: 20093805

Centisome position: 21.37

GC content: 60.6

Gene sequence:

>1071_bases
GTGCACGTGTTAATAGCTTCAGGGGATGGCGGACATCTCACGAGGGCACTCGCCCTCGCCGAGGAGTTATCCGATCGAGG
ACATGACGTGACGTTCGCCGTCAATGAAGACTCCGATCAGGCCGTAGAACGGCTCAAGAAGGCGGGCTTCGAAGAGTACG
TAGGTCTGCCGAGACCCAGGAGGATGGGTGATACCTCCTGGAAGGCCGCTCTGGGCGGGCTGAAGAACTACCTAGCGGCT
TCCAAAGTACTCCGTGACGTGCGGCCCGATCTAATCCTGTCCACGGGGGCCGGTGTGGCTATCGGGCCGATGATCGCCGG
GAAGTTCAAGCGATTACCCGTGGCACATTACGAGCCGACCGACGTAGTCTCCGTCTCGGGTAAGGTCGCGAAGTTGTGCG
CAGACATCATCGGAGTCTGGGATGAGGATATGGCCGAGTACTACGGCGATCGGGTGATCAACGTCGGTATCGTGTTGCCT
CGGAGCTTCGAGGAGGCCGATCCGGAGGAGGCCCGGGAGAAGTACGACCTGGGAGATCGAGTACTCGTGTGGACTACGGG
CTCGGCCGGCTACAAGCCCGCTCTGGAGGGGCTCGTCAGGTGCGCCGAAGAGGGGCTACTTAGGGATTGGGAAGTGGTCG
TGAACACGGGGAACGCCATGGATCCCAAGCGCTTGAAACGAGCGCTGAATGGACTGTGTTCTGGGATCGTGGTGAAGCGC
TTCTTCCACGATTTTCCGGCCCTGTTGAAGGCAGCCGATCTCGTCGTGTGCCTAGGGGGAGCCACTCCCGTGGAGGCCGC
CGCGCTGGGGAAGCCGGTGGTGGTTCTGCCCAGGAGGGACGTGCTCAGGGACCATCAATACGTTACCGCTAAGAAGTTGG
AGAAACGCGGTGTTGCGGTGGCAGCCGAAGACGCTTCTAACCCCGAAGAGGTCGTAAAAGCCGTGAGTCGAGCCCTGAGC
ATCGATCCCGAAGACCTGAAGCGTATGGGGGAGAGAGGTAAGGAACTCTTCGGGGGCAACGCTCGGGAACGGTTCATCGA
CCTCTGTGAGGAGCTCGTCGCATCGGGATGA

Upstream 100 bases:

>100_bases
GTGACAGTGTGGCAGCCGCGAAGAACGTGCTCTTACCCACGTTCGGCTTGCCGACTATGCCTACCTGCACTCCCAACCGG
TAGTCCCCGGGGGAACGTCC

Downstream 100 bases:

>100_bases
GGAGGTCCCCGCTATCCGAACGTGTGAGGAACTCTCCCTTTGCCGACCGACTATAACCCAGTTACAGAGAACCCCCTCTT
CTCTAAATCCTCCAGCAGCT

Product: UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MHVLIASGDGGHLTRALALAEELSDRGHDVTFAVNEDSDQAVERLKKAGFEEYVGLPRPRRMGDTSWKAALGGLKNYLAA
SKVLRDVRPDLILSTGAGVAIGPMIAGKFKRLPVAHYEPTDVVSVSGKVAKLCADIIGVWDEDMAEYYGDRVINVGIVLP
RSFEEADPEEAREKYDLGDRVLVWTTGSAGYKPALEGLVRCAEEGLLRDWEVVVNTGNAMDPKRLKRALNGLCSGIVVKR
FFHDFPALLKAADLVVCLGGATPVEAAALGKPVVVLPRRDVLRDHQYVTAKKLEKRGVAVAAEDASNPEEVVKAVSRALS
IDPEDLKRMGERGKELFGGNARERFIDLCEELVASG

Sequences:

>Translated_356_residues
MHVLIASGDGGHLTRALALAEELSDRGHDVTFAVNEDSDQAVERLKKAGFEEYVGLPRPRRMGDTSWKAALGGLKNYLAA
SKVLRDVRPDLILSTGAGVAIGPMIAGKFKRLPVAHYEPTDVVSVSGKVAKLCADIIGVWDEDMAEYYGDRVINVGIVLP
RSFEEADPEEAREKYDLGDRVLVWTTGSAGYKPALEGLVRCAEEGLLRDWEVVVNTGNAMDPKRLKRALNGLCSGIVVKR
FFHDFPALLKAADLVVCLGGATPVEAAALGKPVVVLPRRDVLRDHQYVTAKKLEKRGVAVAAEDASNPEEVVKAVSRALS
IDPEDLKRMGERGKELFGGNARERFIDLCEELVASG
>Mature_356_residues
MHVLIASGDGGHLTRALALAEELSDRGHDVTFAVNEDSDQAVERLKKAGFEEYVGLPRPRRMGDTSWKAALGGLKNYLAA
SKVLRDVRPDLILSTGAGVAIGPMIAGKFKRLPVAHYEPTDVVSVSGKVAKLCADIIGVWDEDMAEYYGDRVINVGIVLP
RSFEEADPEEAREKYDLGDRVLVWTTGSAGYKPALEGLVRCAEEGLLRDWEVVVNTGNAMDPKRLKRALNGLCSGIVVKR
FFHDFPALLKAADLVVCLGGATPVEAAALGKPVVVLPRRDVLRDHQYVTAKKLEKRGVAVAAEDASNPEEVVKAVSRALS
IDPEDLKRMGERGKELFGGNARERFIDLCEELVASG

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38598; Mature: 38598

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLIASGDGGHLTRALALAEELSDRGHDVTFAVNEDSDQAVERLKKAGFEEYVGLPRPR
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHCCCCCC
RMGDTSWKAALGGLKNYLAASKVLRDVRPDLILSTGAGVAIGPMIAGKFKRLPVAHYEPT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHCCCCCCCCCC
DVVSVSGKVAKLCADIIGVWDEDMAEYYGDRVINVGIVLPRSFEEADPEEAREKYDLGDR
CEEECCHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCE
VLVWTTGSAGYKPALEGLVRCAEEGLLRDWEVVVNTGNAMDPKRLKRALNGLCSGIVVKR
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHH
FFHDFPALLKAADLVVCLGGATPVEAAALGKPVVVLPRRDVLRDHQYVTAKKLEKRGVAV
HHHHHHHHHHHHCEEEEECCCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCEE
AAEDASNPEEVVKAVSRALSIDPEDLKRMGERGKELFGGNARERFIDLCEELVASG
EECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHVLIASGDGGHLTRALALAEELSDRGHDVTFAVNEDSDQAVERLKKAGFEEYVGLPRPR
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHCCCCCC
RMGDTSWKAALGGLKNYLAASKVLRDVRPDLILSTGAGVAIGPMIAGKFKRLPVAHYEPT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHCCCCCCCCCC
DVVSVSGKVAKLCADIIGVWDEDMAEYYGDRVINVGIVLPRSFEEADPEEAREKYDLGDR
CEEECCHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCE
VLVWTTGSAGYKPALEGLVRCAEEGLLRDWEVVVNTGNAMDPKRLKRALNGLCSGIVVKR
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHH
FFHDFPALLKAADLVVCLGGATPVEAAALGKPVVVLPRRDVLRDHQYVTAKKLEKRGVAV
HHHHHHHHHHHHCEEEEECCCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCEE
AAEDASNPEEVVKAVSRALSIDPEDLKRMGERGKELFGGNARERFIDLCEELVASG
EECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA