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The map label for this gene is CbiD

Identifier: 20093772

GI number: 20093772

Start: 325541

End: 326770

Strand: Reverse

Name: CbiD

Synonym: MK0334

Alternate gene names: 20093772

Gene position: 326770-325541 (Counterclockwise)

Preceding gene: 20093773

Following gene: 20093770

Centisome position: 19.28

GC content: 67.56

Gene sequence:

>1230_bases
ATGAACGACCTCCTCGACCCGATACGCGGGATCCCCGTAGACCTCGAGCTCGTGAGGAGAGAACTAGACGTCGACCTCCC
CACGGCCCGGTACCTGGTACGCACCGGCCTGATCACGACCGACGGAGCCCGGGTGCTCCGGCGCGGACCCACCACGGGGA
CCTGCGCCACCGCCGCCGCCAAGGCCGCGGCCATCCGGCTCCTGGAGGGCAGGACGGTACGGACCGTCCGCGTCCGCCTC
CCGGTGGGGACCGTTATAGGCGTCCGGATCTCACGCGTCGGTGGAGACCCGTCCGAAGCCAGGGTGAGGAAACCCGGGAG
CGACGACCACGTGGACGTCACTACGGGCGTCACCATCGCCGCCCGGGTCGAGGAGACCGGTTCCGAGGGTGTCGAGATAC
GCGCGGGTAGGGGGGTCGGTGAGACACCCTCCGGGAAACCCGCGATCTCCGAGGCCGTGCGGGAACAGATCGTTGACAAC
CTGCGCTACCTCGTCGACTCCTACGGAGTCGGGCTCAGGGTCACGATCGAGGTGCCGGACGGCGAGGAGATCGCCCGCAA
GACCCTGGCACACCGTCACGGGATAGAGGGAGGCATCTCGATCCTGGGGACGAAGGGCCTGGTGGACCCGAACTCCGAGG
AGGCGATCGAGGGGTCGATCCGAAGCGATCTCCGGTACGTCGAACGCGTCCCCTGCCTGGTCACCGGGTACAGGACCATG
GACCGGGCGCGACGACTCGGGATACCCTCCCGTGATATCGTCAACTGCCACGGCAGGTACGACCTGGCGCTCGAGGCCGT
GAAGACCGGTGTCCCGGCGGACGGAGAGGTCAAGCGGTTCGACGCCGTGTTGATCTTCGGGATGCCCGGTAAGCTGCTCA
AGCTCGCGGCGGGCGCGTACAACACGCACGCCAAGGTGGCCGACGCGCGCCGCGAGTCCCTGGTGACCCGGCTGGTCGAG
ATCGGCCGGCCCGACCTCGCGGTCGAGGCGGCGCGTCACGAGGGGCTAATATCCGAGTTTCTGAGGAGTCTCGATCCGGA
CGTCCGTCGGGAGCTGTTCGAACGCGTCTGCGAGCTCGTCGAGGAGCGGGTGAGCTCCGATCACGACCTCGAGTGCGGGT
GCGCGCTGTATTTTCGTGCGGATGACTCGGAAGAAGTCGTCGAGGGGGAGGGCTGGAAGCGGCTGGTTCGCGGGTACGAT
GATGATCTAATCGGCCGTCCGAAGGGATGA

Upstream 100 bases:

>100_bases
CGGCCCTCAACCCGGCGTTCGACGTCACGCCACCGGAGCTCATCGACGCGATCATCACCGAGAAGGGCGTCGTCGAGCCC
CAGGAGGTGGCCGACCTGGT

Downstream 100 bases:

>100_bases
GGACACAGGCCGCCGCTGATCCACGACGGTGTGAACCGTCGGAAGACCCTCTCCGGATGATGATCTAATCGGCCGCCCGA
TCGGTGAGGACGTTCCAGGC

Product: cobalamin biosynthesis protein CbiD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNDLLDPIRGIPVDLELVRRELDVDLPTARYLVRTGLITTDGARVLRRGPTTGTCATAAAKAAAIRLLEGRTVRTVRVRL
PVGTVIGVRISRVGGDPSEARVRKPGSDDHVDVTTGVTIAARVEETGSEGVEIRAGRGVGETPSGKPAISEAVREQIVDN
LRYLVDSYGVGLRVTIEVPDGEEIARKTLAHRHGIEGGISILGTKGLVDPNSEEAIEGSIRSDLRYVERVPCLVTGYRTM
DRARRLGIPSRDIVNCHGRYDLALEAVKTGVPADGEVKRFDAVLIFGMPGKLLKLAAGAYNTHAKVADARRESLVTRLVE
IGRPDLAVEAARHEGLISEFLRSLDPDVRRELFERVCELVEERVSSDHDLECGCALYFRADDSEEVVEGEGWKRLVRGYD
DDLIGRPKG

Sequences:

>Translated_409_residues
MNDLLDPIRGIPVDLELVRRELDVDLPTARYLVRTGLITTDGARVLRRGPTTGTCATAAAKAAAIRLLEGRTVRTVRVRL
PVGTVIGVRISRVGGDPSEARVRKPGSDDHVDVTTGVTIAARVEETGSEGVEIRAGRGVGETPSGKPAISEAVREQIVDN
LRYLVDSYGVGLRVTIEVPDGEEIARKTLAHRHGIEGGISILGTKGLVDPNSEEAIEGSIRSDLRYVERVPCLVTGYRTM
DRARRLGIPSRDIVNCHGRYDLALEAVKTGVPADGEVKRFDAVLIFGMPGKLLKLAAGAYNTHAKVADARRESLVTRLVE
IGRPDLAVEAARHEGLISEFLRSLDPDVRRELFERVCELVEERVSSDHDLECGCALYFRADDSEEVVEGEGWKRLVRGYD
DDLIGRPKG
>Mature_409_residues
MNDLLDPIRGIPVDLELVRRELDVDLPTARYLVRTGLITTDGARVLRRGPTTGTCATAAAKAAAIRLLEGRTVRTVRVRL
PVGTVIGVRISRVGGDPSEARVRKPGSDDHVDVTTGVTIAARVEETGSEGVEIRAGRGVGETPSGKPAISEAVREQIVDN
LRYLVDSYGVGLRVTIEVPDGEEIARKTLAHRHGIEGGISILGTKGLVDPNSEEAIEGSIRSDLRYVERVPCLVTGYRTM
DRARRLGIPSRDIVNCHGRYDLALEAVKTGVPADGEVKRFDAVLIFGMPGKLLKLAAGAYNTHAKVADARRESLVTRLVE
IGRPDLAVEAARHEGLISEFLRSLDPDVRRELFERVCELVEERVSSDHDLECGCALYFRADDSEEVVEGEGWKRLVRGYD
DDLIGRPKG

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_METKA (Q8TYG5)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613619.1
- ProteinModelPortal:   Q8TYG5
- SMR:   Q8TYG5
- GeneID:   1477637
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0334
- NMPDR:   fig|190192.1.peg.332
- OMA:   MPGKLAK
- BioCyc:   MKAN190192:MK0334-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 44576; Mature: 44576

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLLDPIRGIPVDLELVRRELDVDLPTARYLVRTGLITTDGARVLRRGPTTGTCATAAA
CCCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHCCEECCCHHHHHCCCCCCHHHHHHH
KAAAIRLLEGRTVRTVRVRLPVGTVIGVRISRVGGDPSEARVRKPGSDDHVDVTTGVTIA
HHHHHHHHCCCEEEEEEEEECCCEEEEEEEEECCCCCCHHHCCCCCCCCCEEEECCEEEE
ARVEETGSEGVEIRAGRGVGETPSGKPAISEAVREQIVDNLRYLVDSYGVGLRVTIEVPD
EEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GEEIARKTLAHRHGIEGGISILGTKGLVDPNSEEAIEGSIRSDLRYVERVPCLVTGYRTM
CHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEECHHHH
DRARRLGIPSRDIVNCHGRYDLALEAVKTGVPADGEVKRFDAVLIFGMPGKLLKLAAGAY
HHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHCCC
NTHAKVADARRESLVTRLVEIGRPDLAVEAARHEGLISEFLRSLDPDVRRELFERVCELV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EERVSSDHDLECGCALYFRADDSEEVVEGEGWKRLVRGYDDDLIGRPKG
HHHCCCCCCCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNDLLDPIRGIPVDLELVRRELDVDLPTARYLVRTGLITTDGARVLRRGPTTGTCATAAA
CCCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHCCEECCCHHHHHCCCCCCHHHHHHH
KAAAIRLLEGRTVRTVRVRLPVGTVIGVRISRVGGDPSEARVRKPGSDDHVDVTTGVTIA
HHHHHHHHCCCEEEEEEEEECCCEEEEEEEEECCCCCCHHHCCCCCCCCCEEEECCEEEE
ARVEETGSEGVEIRAGRGVGETPSGKPAISEAVREQIVDNLRYLVDSYGVGLRVTIEVPD
EEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GEEIARKTLAHRHGIEGGISILGTKGLVDPNSEEAIEGSIRSDLRYVERVPCLVTGYRTM
CHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEECHHHH
DRARRLGIPSRDIVNCHGRYDLALEAVKTGVPADGEVKRFDAVLIFGMPGKLLKLAAGAY
HHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHCCC
NTHAKVADARRESLVTRLVEIGRPDLAVEAARHEGLISEFLRSLDPDVRRELFERVCELV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EERVSSDHDLECGCALYFRADDSEEVVEGEGWKRLVRGYDDDLIGRPKG
HHHCCCCCCCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014