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The map label for this gene is mrp [C]

Identifier: 20093680

GI number: 20093680

Start: 228106

End: 228978

Strand: Reverse

Name: mrp [C]

Synonym: MK0240

Alternate gene names: 20093680

Gene position: 228978-228106 (Counterclockwise)

Preceding gene: 20093681

Following gene: 20093677

Centisome position: 13.51

GC content: 65.18

Gene sequence:

>873_bases
GTGAGTCCCTTGGCCGAGGGGAACGAGCCACGTGAGGGCCACCCGCACCACCCGTCCCGAGAGGAGCTAGAGAAGCGCCT
CGAGAAGGAACGCGAAGCCATCGAGAAGAACCTGGAGAGCGTCGAGCACGTCCTTGTCGTCATGAGCGGCAAAGGCGGCG
TGGGTAAGACCACCGTCTCGGTGAACCTCGCGCTCGCGCTGGCCGAGGACGACGAGGTGGGTATCCTGGACCTGGACATC
CACGGACCGAACGTACCTGAGCAACTCGGGGTCACGGAGCCCCCACAGGGAACGCCCGCCGGTCTGTTCCCGCTCTCGGG
CTACCGTGACGTGAAAGTGATGTCCATCGGCACCATGCTGGAGCGCGAGGACCTCCCCGTCCTCTGGCGTGGGCCGCGCA
AGTCCGGCTTCATCCGCGAGATCCTCGTCAAGACGCGCTGGGGCGACCTGGACTACCTGATCATCGACATGCCTCCTGGA
ACCGGTGACGAGGTCATGACGGCGCTGCAGATGCTCCCCGAGGACGCCCGTAACGTGCTCCTGGTCGCCAGCCCCGAGTC
CCTGGCGTTCTCCGACGTCGTGAAGGCCGGTGAAGCCGTCGATAAGCTGGAGGCTCGGTTGATCGGGATCGTCAGTAACA
TGCACGGGATCGTCTGCCCCGAGTGCGGGAGCACGATCGAGTACTTCTCGGACGACTACTCGGAGAAGCTCGCGGAGCGA
TTCGACACCGAGGTCCTCGCCCGGATACCCCTAGACCCGGAGGCGAAGCGGAAGGCCGAGGAGGAAGGTAAACCGTTCGT
CATCGCCGCCCCCGACTCGCGAGTCTCCGAGGCCTTCTCCGAGCTCGCTGAAGCCGTTCGTGACCGCCTCTGA

Upstream 100 bases:

>100_bases
TTAGCCTGGGATCGGTCCATCGGTACCGTCGCTCGACGTGGGCACACAGGGGAACCGGTTTTAAGAGCCTCGAACGACTC
ATTAGGTGCACCTAACCGGG

Downstream 100 bases:

>100_bases
AGGCGCCCTCGGGCAACCTTCCGCCCCCCGGTAGAACGTTTCATCCTCCGATCGACGTGCGAGCCGTCAGTGGGGTCACC
TCCTCATCGCGGAGCGCGTG

Product: chromosome partitioning ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSPLAEGNEPREGHPHHPSREELEKRLEKEREAIEKNLESVEHVLVVMSGKGGVGKTTVSVNLALALAEDDEVGILDLDI
HGPNVPEQLGVTEPPQGTPAGLFPLSGYRDVKVMSIGTMLEREDLPVLWRGPRKSGFIREILVKTRWGDLDYLIIDMPPG
TGDEVMTALQMLPEDARNVLLVASPESLAFSDVVKAGEAVDKLEARLIGIVSNMHGIVCPECGSTIEYFSDDYSEKLAER
FDTEVLARIPLDPEAKRKAEEEGKPFVIAAPDSRVSEAFSELAEAVRDRL

Sequences:

>Translated_290_residues
MSPLAEGNEPREGHPHHPSREELEKRLEKEREAIEKNLESVEHVLVVMSGKGGVGKTTVSVNLALALAEDDEVGILDLDI
HGPNVPEQLGVTEPPQGTPAGLFPLSGYRDVKVMSIGTMLEREDLPVLWRGPRKSGFIREILVKTRWGDLDYLIIDMPPG
TGDEVMTALQMLPEDARNVLLVASPESLAFSDVVKAGEAVDKLEARLIGIVSNMHGIVCPECGSTIEYFSDDYSEKLAER
FDTEVLARIPLDPEAKRKAEEEGKPFVIAAPDSRVSEAFSELAEAVRDRL
>Mature_289_residues
SPLAEGNEPREGHPHHPSREELEKRLEKEREAIEKNLESVEHVLVVMSGKGGVGKTTVSVNLALALAEDDEVGILDLDIH
GPNVPEQLGVTEPPQGTPAGLFPLSGYRDVKVMSIGTMLEREDLPVLWRGPRKSGFIREILVKTRWGDLDYLIIDMPPGT
GDEVMTALQMLPEDARNVLLVASPESLAFSDVVKAGEAVDKLEARLIGIVSNMHGIVCPECGSTIEYFSDDYSEKLAERF
DTEVLARIPLDPEAKRKAEEEGKPFVIAAPDSRVSEAFSELAEAVRDRL

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=259, Percent_Identity=38.996138996139, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI118572611, Length=263, Percent_Identity=34.6007604562738, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI157384956, Length=260, Percent_Identity=38.8461538461538, Blast_Score=167, Evalue=7e-42,
Organism=Escherichia coli, GI87082045, Length=264, Percent_Identity=37.5, Blast_Score=157, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143050, Length=264, Percent_Identity=37.5, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6321347, Length=276, Percent_Identity=35.8695652173913, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322188, Length=263, Percent_Identity=32.6996197718631, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667611, Length=260, Percent_Identity=39.2307692307692, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI221511043, Length=252, Percent_Identity=38.4920634920635, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19921440, Length=259, Percent_Identity=32.4324324324324, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 31826; Mature: 31694

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLAEGNEPREGHPHHPSREELEKRLEKEREAIEKNLESVEHVLVVMSGKGGVGKTTVS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEE
VNLALALAEDDEVGILDLDIHGPNVPEQLGVTEPPQGTPAGLFPLSGYRDVKVMSIGTML
EEEEEEEECCCCEEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHH
EREDLPVLWRGPRKSGFIREILVKTRWGDLDYLIIDMPPGTGDEVMTALQMLPEDARNVL
HHCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEE
LVASPESLAFSDVVKAGEAVDKLEARLIGIVSNMHGIVCPECGSTIEYFSDDYSEKLAER
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCHHHHHHHHH
FDTEVLARIPLDPEAKRKAEEEGKPFVIAAPDSRVSEAFSELAEAVRDRL
HCHHHHHCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPLAEGNEPREGHPHHPSREELEKRLEKEREAIEKNLESVEHVLVVMSGKGGVGKTTVS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEE
VNLALALAEDDEVGILDLDIHGPNVPEQLGVTEPPQGTPAGLFPLSGYRDVKVMSIGTML
EEEEEEEECCCCEEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHH
EREDLPVLWRGPRKSGFIREILVKTRWGDLDYLIIDMPPGTGDEVMTALQMLPEDARNVL
HHCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEE
LVASPESLAFSDVVKAGEAVDKLEARLIGIVSNMHGIVCPECGSTIEYFSDDYSEKLAER
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCHHHHHHHHH
FDTEVLARIPLDPEAKRKAEEEGKPFVIAAPDSRVSEAFSELAEAVRDRL
HCHHHHHCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]