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The map label for this gene is fno [H]

Identifier: 20093673

GI number: 20093673

Start: 218648

End: 219319

Strand: Direct

Name: fno [H]

Synonym: MK0233

Alternate gene names: 20093673

Gene position: 218648-219319 (Clockwise)

Preceding gene: 20093672

Following gene: 20093674

Centisome position: 12.9

GC content: 62.95

Gene sequence:

>672_bases
GTGCGGCTGGCTTTCATCGGAGGGACCGGCCATCAAGGGTTCGGACTCGCGCTGAGACTGGCGGCGGCGGGACACCACGT
GATCATAGGATCGAGGGAGGAGGAACGCGCCGTTAAAGCCGCGGAGGAGGCCGAGGAGATCCTGGCAGAGCACGGGTATG
AGGACGTCACCGTTGAAGGTCGCGAGAATTCCGATGCCGCCGCCGAGGCGGAGGTTGTGTTCCTGACTGTCCCGTTCTTC
GCTGTCATCGACACGGTGAAGGCGATCCGGGACTCCCTCGACGAGGACGCGATCGTCGTGGACGTCACGGTACCGTTGGA
AACCGCCGTAGGAGGCAAGCCCACCCGGCTGATCAGACCGTGGGCCGGATCGGCGGCTGAAACCGTGCAGTCCCTGGTCA
ACAACCCCGTGGTATCCGCGTTCGAAAACGTCTCCGCCGAGTCACTTCGGGACCTGGAGAAAGAGGTTAAGTGCGACGTG
GTGGTGTGTTCGGACCACGAGGACGCGAAGCGCACCGTCATGGAGCTCGCGGAGGAGATACCGGGAGTTCGGGCGATAGA
CGGCGGACCGTTGGAGAACGCCAGGATCGTGGAGTCCATCACGGCACTGCTGATCAGCCTCAACATGCGGTACGGTAAGG
AGGACGTCGGGATCAGGTTCACCAACCTGTAG

Upstream 100 bases:

>100_bases
TTCGACGCCACCGAAGCGGTGGTACGGGACAACGCCCTACAGCTTTTCTAACCCGGCACCCTCTTAACGCCGTCCCTCCC
CGCCCACCCGGGGTGCGAAC

Downstream 100 bases:

>100_bases
GGGGTCCGCCCGCGTCCCGATCTTCACCCCATCCGCTCGGGACTTTGTCTTCATCCCCCAGGGGGCGCCGCGTTGAGGGA
TTTTCTGAGGTGCGTAGAGG

Product: dinucleotide-binding protein

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRLAFIGGTGHQGFGLALRLAAAGHHVIIGSREEERAVKAAEEAEEILAEHGYEDVTVEGRENSDAAAEAEVVFLTVPFF
AVIDTVKAIRDSLDEDAIVVDVTVPLETAVGGKPTRLIRPWAGSAAETVQSLVNNPVVSAFENVSAESLRDLEKEVKCDV
VVCSDHEDAKRTVMELAEEIPGVRAIDGGPLENARIVESITALLISLNMRYGKEDVGIRFTNL

Sequences:

>Translated_223_residues
MRLAFIGGTGHQGFGLALRLAAAGHHVIIGSREEERAVKAAEEAEEILAEHGYEDVTVEGRENSDAAAEAEVVFLTVPFF
AVIDTVKAIRDSLDEDAIVVDVTVPLETAVGGKPTRLIRPWAGSAAETVQSLVNNPVVSAFENVSAESLRDLEKEVKCDV
VVCSDHEDAKRTVMELAEEIPGVRAIDGGPLENARIVESITALLISLNMRYGKEDVGIRFTNL
>Mature_223_residues
MRLAFIGGTGHQGFGLALRLAAAGHHVIIGSREEERAVKAAEEAEEILAEHGYEDVTVEGRENSDAAAEAEVVFLTVPFF
AVIDTVKAIRDSLDEDAIVVDVTVPLETAVGGKPTRLIRPWAGSAAETVQSLVNNPVVSAFENVSAESLRDLEKEVKCDV
VVCSDHEDAKRTVMELAEEIPGVRAIDGGPLENARIVESITALLISLNMRYGKEDVGIRFTNL

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 23975; Mature: 23975

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAFIGGTGHQGFGLALRLAAAGHHVIIGSREEERAVKAAEEAEEILAEHGYEDVTVEG
CEEEEECCCCCCCHHHEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
RENSDAAAEAEVVFLTVPFFAVIDTVKAIRDSLDEDAIVVDVTVPLETAVGGKPTRLIRP
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHCCCCCCCEEECC
WAGSAAETVQSLVNNPVVSAFENVSAESLRDLEKEVKCDVVVCSDHEDAKRTVMELAEEI
CCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHC
PGVRAIDGGPLENARIVESITALLISLNMRYGKEDVGIRFTNL
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MRLAFIGGTGHQGFGLALRLAAAGHHVIIGSREEERAVKAAEEAEEILAEHGYEDVTVEG
CEEEEECCCCCCCHHHEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
RENSDAAAEAEVVFLTVPFFAVIDTVKAIRDSLDEDAIVVDVTVPLETAVGGKPTRLIRP
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHCCCCCCCEEECC
WAGSAAETVQSLVNNPVVSAFENVSAESLRDLEKEVKCDVVVCSDHEDAKRTVMELAEEI
CCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHC
PGVRAIDGGPLENARIVESITALLISLNMRYGKEDVGIRFTNL
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]