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The map label for this gene is ybiV [C]

Identifier: 20093643

GI number: 20093643

Start: 195719

End: 196417

Strand: Direct

Name: ybiV [C]

Synonym: MK0203

Alternate gene names: 20093643

Gene position: 195719-196417 (Clockwise)

Preceding gene: 20093641

Following gene: 20093644

Centisome position: 11.55

GC content: 60.66

Gene sequence:

>699_bases
GTGACGTCCCTCGTCATCACGGATATCGACGGCACGATCACGGGAGATGATAGAGCCGTCCACCTAAAGTGCATCCGGTA
CCTGCGGGAACTACAGAAACGCGGGATACCGGTTGGGATCGCCACCGGTAACACCCTCTGTTACTCCAGATCGGCGGCGA
CCCTCCTCGGCTTCGAGGGTCCATTGATTGCGGAGAACGGAGGGATAGTCGCCGTGGACGACGAGGAGATCAGCACGGTG
CCCGAAGAGGACATCGAGTTAATTCAGGAGGCGTACCGAGAGCTCCGTCGGCGACTCGGTGTGAGGCGTACCGAACCACC
AGGGCTCCGCCGGACCGAGGTCGCTATCTATCGGGATGTACCCATCGAGGAAGTCGAACGCGTGTTGGATGGGCTCGGAT
ACTCCGGCCGTATCGAGGTAGTGGACACGGGCTTCGCGTATCATTTGAAGTCCAAACGGGTGGACAAAGGGAAGGGGCTC
TTAGTCATCTGTGAGCGACTCGGTATCGACCCGGACGACGTGGTGGCCATAGGAGACGGGGACAACGATGCTCCACTGTT
GAAAGCGGCGGGGCTGGGCGTGGCACCCGCGAACGCCACTGAGAACGTCAAACGGATCGCGGACGTAGTACTCGACGCCG
AGAACGGTGAGGGAGTCGCCACCTTCCTTCGGAAGCTCCTCGAGGAGGTGGACGCTTGA

Upstream 100 bases:

>100_bases
ACCTCACCACGTGTTGATGGCCCCTGAGCTTGGGCGGGATGAACTCCAGCTCCGACTCCGCTAGCACGAAACAAAGACGC
GGCATGCGGGGGCTACCCCC

Downstream 100 bases:

>100_bases
AGCTGTATCCGTTAGTCCGTAAAGTGTTGAAGTTGCTGTCGTCGGCCGATTCCATCGGTATCATGGCTGATACCGATGCG
GATGGCGTGTCGGGCGCAGC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTSLVITDIDGTITGDDRAVHLKCIRYLRELQKRGIPVGIATGNTLCYSRSAATLLGFEGPLIAENGGIVAVDDEEISTV
PEEDIELIQEAYRELRRRLGVRRTEPPGLRRTEVAIYRDVPIEEVERVLDGLGYSGRIEVVDTGFAYHLKSKRVDKGKGL
LVICERLGIDPDDVVAIGDGDNDAPLLKAAGLGVAPANATENVKRIADVVLDAENGEGVATFLRKLLEEVDA

Sequences:

>Translated_232_residues
MTSLVITDIDGTITGDDRAVHLKCIRYLRELQKRGIPVGIATGNTLCYSRSAATLLGFEGPLIAENGGIVAVDDEEISTV
PEEDIELIQEAYRELRRRLGVRRTEPPGLRRTEVAIYRDVPIEEVERVLDGLGYSGRIEVVDTGFAYHLKSKRVDKGKGL
LVICERLGIDPDDVVAIGDGDNDAPLLKAAGLGVAPANATENVKRIADVVLDAENGEGVATFLRKLLEEVDA
>Mature_231_residues
TSLVITDIDGTITGDDRAVHLKCIRYLRELQKRGIPVGIATGNTLCYSRSAATLLGFEGPLIAENGGIVAVDDEEISTVP
EEDIELIQEAYRELRRRLGVRRTEPPGLRRTEVAIYRDVPIEEVERVLDGLGYSGRIEVVDTGFAYHLKSKRVDKGKGLL
VICERLGIDPDDVVAIGDGDNDAPLLKAAGLGVAPANATENVKRIADVVLDAENGEGVATFLRKLLEEVDA

Specific function: Catalyzes the dephosphorylation of 2-phosphoglycolate

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal SPP-like hydrolase family

Homologues:

Organism=Escherichia coli, GI1787043, Length=265, Percent_Identity=26.0377358490566, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI2367265, Length=76, Percent_Identity=40.7894736842105, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGP_METKA (Q8TYT9)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613490.1
- ProteinModelPortal:   Q8TYT9
- SMR:   Q8TYT9
- GeneID:   1477506
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0203
- NMPDR:   fig|190192.1.peg.203
- HOGENOM:   HBG551920
- OMA:   VTGNTVQ
- ProtClustDB:   PRK01158
- BioCyc:   MKAN190192:MK0203-MONOMER
- BRENDA:   3.1.3.18
- GO:   GO:0016020
- HAMAP:   MF_01419
- InterPro:   IPR001757
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006382
- InterPro:   IPR006378
- Gene3D:   G3DSA:3.40.50.1000
- PRINTS:   PR00119
- TIGRFAMs:   TIGR01484
- TIGRFAMs:   TIGR01487
- TIGRFAMs:   TIGR01482

Pfam domain/function: PF08282 Hydrolase_3; SSF56784 SSF56784

EC number: =3.1.3.18

Molecular weight: Translated: 25162; Mature: 25031

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01229 COF_2

Important sites: ACT_SITE 8-8 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLVITDIDGTITGDDRAVHLKCIRYLRELQKRGIPVGIATGNTLCYSRSAATLLGFEG
CCEEEEECCCCEEECCCCEEHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCEEEECCC
PLIAENGGIVAVDDEEISTVPEEDIELIQEAYRELRRRLGVRRTEPPGLRRTEVAIYRDV
CEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC
PIEEVERVLDGLGYSGRIEVVDTGFAYHLKSKRVDKGKGLLVICERLGIDPDDVVAIGDG
CHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCCCCCEEEEHHHHCCCHHHEEEECCC
DNDAPLLKAAGLGVAPANATENVKRIADVVLDAENGEGVATFLRKLLEEVDA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLVITDIDGTITGDDRAVHLKCIRYLRELQKRGIPVGIATGNTLCYSRSAATLLGFEG
CEEEEECCCCEEECCCCEEHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCEEEECCC
PLIAENGGIVAVDDEEISTVPEEDIELIQEAYRELRRRLGVRRTEPPGLRRTEVAIYRDV
CEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC
PIEEVERVLDGLGYSGRIEVVDTGFAYHLKSKRVDKGKGLLVICERLGIDPDDVVAIGDG
CHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCCCCCEEEEHHHHCCCHHHEEEECCC
DNDAPLLKAAGLGVAPANATENVKRIADVVLDAENGEGVATFLRKLLEEVDA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014