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The map label for this gene is TyrA_1 [H]

Identifier: 20093519

GI number: 20093519

Start: 74116

End: 74928

Strand: Direct

Name: TyrA_1 [H]

Synonym: MK0079

Alternate gene names: 20093519

Gene position: 74116-74928 (Clockwise)

Preceding gene: 20093518

Following gene: 20093520

Centisome position: 4.37

GC content: 56.46

Gene sequence:

>813_bases
CTGATTTCATACCTGGGGCCGCCAGGCACGTTCACAGAGGAGGCGGCTGAGCGGTTTTCTGAGGAAGAACTTGGGGGAAA
CGGAAAGCTCCAGTCTGCCAGGACTATTACCGCGGTTTTCTCACGTGTAGAGCGAGGTGAGGCGGATTACGGTGTAGTTC
CGTGGGAGAATTCACTGGAGGGATCCGTAGGAGAGACTTTGGATAACTTCCTGCATAGGAGCGTACGCGTGTTCGGCGAG
CTGGTGTTACCGATCGTGCATGCACTGATGTCCGGATCCGAACCGGACGACCGTGAACCCGTGGTCTACTCGCACCCCCA
GGCGTATGAGCAGGCGCGGGAAACGCTGCGAGAGTTACTCGGTAACCACGAGTTCGTACCCACGGCGAGCACCGCCGAAG
CTGCCAAACTGGCGTCGAAGGAGGGTGCTTACGCTCTAGGTCCACCGAGGCTCGCGGAGCGGTTCGGATTGGACATAATG
GAGGAGATAAGACTGGAAAATAACGAGACCAGGTTCGCGATCATCTCGAGGCGCGATAGAGCCCCGACTAAAGAGGACAA
AACATCCGTGGTGTTCTCGGTAACCGATCGTCCGGGTGCTCTACGTGAGATTTTGGGTATCTTCGCGGATCGAGGTATCA
ACCTCACTAAGATCGAATCTCGACCCGCGAAGAGAGGGTTAGGAGACTACGTTTTCTTCCTGGACTTTGAGGGGCACAGG
ATGCTCTATCCCGGGTCCGAAGCGTTGGCAGAACTCCGAGAAAGAACGCCGTTTTCCAAGGTGTTGGGGTCGTACCCCAA
GGTTTTCCCGTAG

Upstream 100 bases:

>100_bases
GGCTACCGCCCGAGTCGGCTTCGATGGGACTAGCCCTGATCGCCGCAGACATAGCCTCCGGAGCCCGGTCGGTGTTGGGG
GTGCGAATTTCTCGCCGCCC

Downstream 100 bases:

>100_bases
GGGGTTAGGACCGTGATCGAGATCAGAATACACGGGAGAGGCGGCCAAGGAGCCGTCACCGCGGCCGAGATCCTGGCGAT
CGCGGCGAAGGAGGATGGGA

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MISYLGPPGTFTEEAAERFSEEELGGNGKLQSARTITAVFSRVERGEADYGVVPWENSLEGSVGETLDNFLHRSVRVFGE
LVLPIVHALMSGSEPDDREPVVYSHPQAYEQARETLRELLGNHEFVPTASTAEAAKLASKEGAYALGPPRLAERFGLDIM
EEIRLENNETRFAIISRRDRAPTKEDKTSVVFSVTDRPGALREILGIFADRGINLTKIESRPAKRGLGDYVFFLDFEGHR
MLYPGSEALAELRERTPFSKVLGSYPKVFP

Sequences:

>Translated_270_residues
MISYLGPPGTFTEEAAERFSEEELGGNGKLQSARTITAVFSRVERGEADYGVVPWENSLEGSVGETLDNFLHRSVRVFGE
LVLPIVHALMSGSEPDDREPVVYSHPQAYEQARETLRELLGNHEFVPTASTAEAAKLASKEGAYALGPPRLAERFGLDIM
EEIRLENNETRFAIISRRDRAPTKEDKTSVVFSVTDRPGALREILGIFADRGINLTKIESRPAKRGLGDYVFFLDFEGHR
MLYPGSEALAELRERTPFSKVLGSYPKVFP
>Mature_270_residues
MISYLGPPGTFTEEAAERFSEEELGGNGKLQSARTITAVFSRVERGEADYGVVPWENSLEGSVGETLDNFLHRSVRVFGE
LVLPIVHALMSGSEPDDREPVVYSHPQAYEQARETLRELLGNHEFVPTASTAEAAKLASKEGAYALGPPRLAERFGLDIM
EEIRLENNETRFAIISRRDRAPTKEDKTSVVFSVTDRPGALREILGIFADRGINLTKIESRPAKRGLGDYVFFLDFEGHR
MLYPGSEALAELRERTPFSKVLGSYPKVFP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=280, Percent_Identity=32.1428571428571, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30050; Mature: 30050

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISYLGPPGTFTEEAAERFSEEELGGNGKLQSARTITAVFSRVERGEADYGVVPWENSLE
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GSVGETLDNFLHRSVRVFGELVLPIVHALMSGSEPDDREPVVYSHPQAYEQARETLRELL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
GNHEFVPTASTAEAAKLASKEGAYALGPPRLAERFGLDIMEEIRLENNETRFAIISRRDR
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHCCCCCCEEEEEECCCC
APTKEDKTSVVFSVTDRPGALREILGIFADRGINLTKIESRPAKRGLGDYVFFLDFEGHR
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEECCCE
MLYPGSEALAELRERTPFSKVLGSYPKVFP
EECCCHHHHHHHHHCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MISYLGPPGTFTEEAAERFSEEELGGNGKLQSARTITAVFSRVERGEADYGVVPWENSLE
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GSVGETLDNFLHRSVRVFGELVLPIVHALMSGSEPDDREPVVYSHPQAYEQARETLRELL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
GNHEFVPTASTAEAAKLASKEGAYALGPPRLAERFGLDIMEEIRLENNETRFAIISRRDR
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHCCCCCCEEEEEECCCC
APTKEDKTSVVFSVTDRPGALREILGIFADRGINLTKIESRPAKRGLGDYVFFLDFEGHR
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEECCCE
MLYPGSEALAELRERTPFSKVLGSYPKVFP
EECCCHHHHHHHHHCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]