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The map label for this gene is Cmk

Identifier: 20093462

GI number: 20093462

Start: 20875

End: 21456

Strand: Reverse

Name: Cmk

Synonym: MK0022

Alternate gene names: 20093462

Gene position: 21456-20875 (Counterclockwise)

Preceding gene: 20093463

Following gene: 20093461

Centisome position: 1.27

GC content: 59.97

Gene sequence:

>582_bases
GTGTTTTCAATCAGCGTAGTCATCACCATCGGCGGCCTCCCGGGATCCGGCACCACCACCATGGCCCGGCGGCTCGCCGA
GCACTACGGCCTTAAGCACGTGTACGCAGGTAAGATATTCCGAGAGATGGCCGAGGAGCGAGGCATGGACCTCGAGGAGT
TCTCCAAAGTCGCGGAGGACAACCCGGACATCGACCTTGAAATCGATCGGAGGCAGCGGGAAGCCGCGGAAGAGGGTGAC
GTAATACTCGAGGGACGCCTAGCGGCCTTCGTTGCGGCCGGCGAACTGGACCATGTGAAAGGTCCCGACCTGGCCACCCT
CAAGATATGGCTCAAAGCTCCGTTAGAAGTGCGCGCCGAGCGGGTAGCGAAGCGCGAAGGGATCGACGTGGAAGAGGCTC
GCCGACGCATTCAGGAACGGGAAAAAAGCGAGTTGAAGCGGTATAAGGAGATCTACGGCGTCGATCCGACGGACCTCTCC
TTGTACGATCTCGTCCTCGACACCTCCCGATGGTCCGAAGACGAGACGTTCTCCATTCTCAAAGCGGCGATAGATCCGCT
GCTGGAGCGTGAGGATCCATGA

Upstream 100 bases:

>100_bases
CAAGGATAAGGTGAGGTACAAGTTCTGGGAGCGCAAGCGAGAGCAGCCGTGGCTGCCAGTACTACCGGACGAGGAACCGC
CGGAGCCCGAGGAATGAGGG

Downstream 100 bases:

>100_bases
CCGAGGTAGGAGTGATAGGCGGCACGGGTTTCCAACCCGGTCTGCCCGAACGCAGGCGGACGGTGTTCACACCCTACGGC
ACTGTACGCGTGGACATCAC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MFSISVVITIGGLPGSGTTTMARRLAEHYGLKHVYAGKIFREMAEERGMDLEEFSKVAEDNPDIDLEIDRRQREAAEEGD
VILEGRLAAFVAAGELDHVKGPDLATLKIWLKAPLEVRAERVAKREGIDVEEARRRIQEREKSELKRYKEIYGVDPTDLS
LYDLVLDTSRWSEDETFSILKAAIDPLLEREDP

Sequences:

>Translated_193_residues
MFSISVVITIGGLPGSGTTTMARRLAEHYGLKHVYAGKIFREMAEERGMDLEEFSKVAEDNPDIDLEIDRRQREAAEEGD
VILEGRLAAFVAAGELDHVKGPDLATLKIWLKAPLEVRAERVAKREGIDVEEARRRIQEREKSELKRYKEIYGVDPTDLS
LYDLVLDTSRWSEDETFSILKAAIDPLLEREDP
>Mature_193_residues
MFSISVVITIGGLPGSGTTTMARRLAEHYGLKHVYAGKIFREMAEERGMDLEEFSKVAEDNPDIDLEIDRRQREAAEEGD
VILEGRLAAFVAAGELDHVKGPDLATLKIWLKAPLEVRAERVAKREGIDVEEARRRIQEREKSELKRYKEIYGVDPTDLS
LYDLVLDTSRWSEDETFSILKAAIDPLLEREDP

Specific function: Unknown

COG id: COG1102

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_METKA (Q8TZB3)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613309.1
- ProteinModelPortal:   Q8TZB3
- GeneID:   1477324
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0022
- NMPDR:   fig|190192.1.peg.22
- HOGENOM:   HBG578180
- OMA:   SGCGNTT
- ProtClustDB:   PRK04182
- BioCyc:   MKAN190192:MK0022-MONOMER
- BRENDA:   2.7.4.14
- GO:   GO:0005737
- HAMAP:   MF_00239
- InterPro:   IPR000850
- InterPro:   IPR011892
- InterPro:   IPR011994
- PANTHER:   PTHR23359
- TIGRFAMs:   TIGR02173

Pfam domain/function: PF00406 ADK; PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 21886; Mature: 21886

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSISVVITIGGLPGSGTTTMARRLAEHYGLKHVYAGKIFREMAEERGMDLEEFSKVAED
CCEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
NPDIDLEIDRRQREAAEEGDVILEGRLAAFVAAGELDHVKGPDLATLKIWLKAPLEVRAE
CCCCEEEECHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCCCCCEEEHEEECCCHHHHHH
RVAKREGIDVEEARRRIQEREKSELKRYKEIYGVDPTDLSLYDLVLDTSRWSEDETFSIL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHH
KAAIDPLLEREDP
HHHHHHHHCCCCC
>Mature Secondary Structure
MFSISVVITIGGLPGSGTTTMARRLAEHYGLKHVYAGKIFREMAEERGMDLEEFSKVAED
CCEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
NPDIDLEIDRRQREAAEEGDVILEGRLAAFVAAGELDHVKGPDLATLKIWLKAPLEVRAE
CCCCEEEECHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCCCCCEEEHEEECCCHHHHHH
RVAKREGIDVEEARRRIQEREKSELKRYKEIYGVDPTDLSLYDLVLDTSRWSEDETFSIL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHH
KAAIDPLLEREDP
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014