| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
Click here to switch to the map view.
The map label for this gene is treB [H]
Identifier: 19746968
GI number: 19746968
Start: 1808804
End: 1810828
Strand: Reverse
Name: treB [H]
Synonym: spyM18_2155
Alternate gene names: 19746968
Gene position: 1810828-1808804 (Counterclockwise)
Preceding gene: 19746970
Following gene: 19746967
Centisome position: 95.56
GC content: 41.53
Gene sequence:
>2025_bases ATGGGAAAATTTGAACAGGATGCTAAAAGTCTTCTAACTGCTATTGGCGGTAAAGAAAACATCAAGGCTGTTACACACTG TGCAACGCGTATGCGTTTTGTTTTGAATGATAATAATAAGGCAAATGTCAAAGAGATTGAAAAAATCTCTGTAGTTAAAG GGACATTTACCAATGCTGGGCAGTTTCAGGTAATCATTGGTAATGATGTTCCAGTTTTTTATAATGACTTTACAGCTGTT TCTGGTATTGAAGGGGTGTCTAAAGAAGCTGCCAAATCAGCAGCTAAAAGTAATCAAAATGCCTTACAACAGGTGATGAC CATGTTGGCTGAGATTTTCACACCTATTATTCCGGCGATTATTGTTGGGGGGCTTATTTTAGGTTTCCGTAATATTTTGG AGAGTGTGCCTTTTGAATTTCTTGGGCAGCAGGTCGAAAAAGGGAAATTAGTTTTTGATGCAGCTGGGGATCCTGTTTGG AATACGATTGTGAGGGTATCTCCTTTCTGGTCAGGGGTTAACCATTTCTTGTGGTTACCAGGGGAAGCTATTTTCCACTT CTTACCAGTTGGGATTACTTGGTCTGTGACGCGTAAGATGGGAACCACTCAAATTTTAGGGATTGTCCTTGGTATCTGTT TGGTGTCACCACAATTATTGAATGCTTATGCGGTAGCAGGAACGCCTGCTGCTGAGATTGCCAAAAACTGGGTTTGGGAT TTTGGTTTCTTTATCATTAATCGTATTGGGTATCAGGCACAGGTTATTCCAGCCCTTTTAGCTGGTCTGTCCCTTGCTTA TCTTGAAATTTTCTGGCGTAAACGGATTCCAGAAGTGGTCTCAATGATTTTTGTGCCATTCCTTTCTTTGATTCCAGCTT TGATTTTAGCGCATACGGTATTGGGGCCAATCGGTTGGACTATTGGTAAAGGGATTTCCTTTGTTGTGTTAGCTGGATTG ACTGGTCCTGTTAAATGGCTATTCGGTGCTATCTTTGGTGCCTTGTATGCTCCGCTAGTTATTACTGGTTTACATCACAT GACAAATGCCATTGATACCCAATTAATTGCTGATACTGCAACTCGTACAACTGGTTTGTGGCCAATGATTGCTCTTTCAA ATATCGCTCAAGGGTCAGCCGTTTTTGCTTACTATTTAATGAATCGTCATGAAGAACGTGAGGCTGAAATATCGCTTCCT GCAGCAATTTCTGCTTACCTTGGGGTAACTGAGCCTGCCTTATTTGGGGTTAATGTTAAATACGTTTATCCTTTTGTAGC CGGAATGATTGGCTCAGGTATTGCGGGTCTCTTATCAACATCCTTTAATGTTCAGGCAAATTCTATTGGTGTTGGTGGCT TACCAGGTTTCATGGCTATCAATGTGAAGTACATGATTCCATTCTTCATCTGTATGGCAGTAGCCATTGTGGTGCCGATG TTTTTAACATTCTTTTTCCGTAAATCACATATCATGACTAAGACAGAAGATGAAGCTAAACTACCTGAGACACCCGTTTC AGAGGCTCCTGCAGCAACTGCTCCACATAAGACTATGCAAGGAACAGTTATCACTTTAACAAGCCCTTTAACGGGTGAAG TTAAAGCGTTGTCTGAAGCTGTTGATCCTGTCTTTGCACAGGGAGTTATGGGCCAAGGTGCTCTTCTTCAACCGACAGAA GGGGTGTTAGTAGCGCCTTGTGATGCTGAAGTATCGGTCTTGTTCCCAACTAAACACGCTATTTGTTTGGTGACGACTGA AGGTTTGGAATTATTGATGCATATTGGCATGGATACGGTTAACTTAGATGGTCAAGGATTTGAAGCTTTGGTGAAGCAAG GTGATCAGGTTAAGGCTGGACAAACATTGATTCAATTTGATATAGCAGCTATTTCTGAAGCTGGATACGCCACTGAAACG CCTCTTGTGGTGACTAATCAAGATGCTTTTACGGTAACTGTTGAAGGTAACTTACCGCATCAGATTAAGGCTAATGATAA GTTAGCAGTAGCGATGAAAAAGTAG
Upstream 100 bases:
>100_bases TACAATAAAGGTGTCAATCATATTTTATCTAAGAATTTGAATATTTCATTTTGACGTTGCTTGTTAAAAGCAACTAGAAC AAAGGACTAGGGGATGTCAC
Downstream 100 bases:
>100_bases GTTTACTAGGGAGAAAACGTTCAGGAACTGAGATCAGTTCCTGAAACTATTTTAGGGAGGAAAACTCATGACAATTGATA AAAAGAAAGTCGTCTATCAA
Product: PTS system enzyme II
Products: NA
Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]
Number of amino acids: Translated: 674; Mature: 673
Protein sequence:
>674_residues MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVKEIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAV SGIEGVSKEAAKSAAKSNQNALQQVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQLLNAYAVAGTPAAEIAKNWVWD FGFFIINRIGYQAQVIPALLAGLSLAYLEIFWRKRIPEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGL TGPVKWLFGAIFGALYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAEISLP AAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTSFNVQANSIGVGGLPGFMAINVKYMIPFFICMAVAIVVPM FLTFFFRKSHIMTKTEDEAKLPETPVSEAPAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTE GVLVAPCDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLIQFDIAAISEAGYATET PLVVTNQDAFTVTVEGNLPHQIKANDKLAVAMKK
Sequences:
>Translated_674_residues MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVKEIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAV SGIEGVSKEAAKSAAKSNQNALQQVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQLLNAYAVAGTPAAEIAKNWVWD FGFFIINRIGYQAQVIPALLAGLSLAYLEIFWRKRIPEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGL TGPVKWLFGAIFGALYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAEISLP AAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTSFNVQANSIGVGGLPGFMAINVKYMIPFFICMAVAIVVPM FLTFFFRKSHIMTKTEDEAKLPETPVSEAPAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTE GVLVAPCDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLIQFDIAAISEAGYATET PLVVTNQDAFTVTVEGNLPHQIKANDKLAVAMKK >Mature_673_residues GKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVKEIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVS GIEGVSKEAAKSAAKSNQNALQQVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVWN TIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQLLNAYAVAGTPAAEIAKNWVWDF GFFIINRIGYQAQVIPALLAGLSLAYLEIFWRKRIPEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLT GPVKWLFGAIFGALYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAEISLPA AISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTSFNVQANSIGVGGLPGFMAINVKYMIPFFICMAVAIVVPMF LTFFFRKSHIMTKTEDEAKLPETPVSEAPAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEG VLVAPCDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLIQFDIAAISEAGYATETP LVVTNQDAFTVTVEGNLPHQIKANDKLAVAMKK
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI2367362, Length=499, Percent_Identity=48.6973947895792, Blast_Score=417, Evalue=1e-117, Organism=Escherichia coli, GI1790159, Length=678, Percent_Identity=27.8761061946903, Blast_Score=238, Evalue=1e-63, Organism=Escherichia coli, GI48994906, Length=523, Percent_Identity=28.4894837476099, Blast_Score=149, Evalue=4e-37, Organism=Escherichia coli, GI1788757, Length=135, Percent_Identity=37.7777777777778, Blast_Score=109, Evalue=7e-25, Organism=Escherichia coli, GI1786894, Length=130, Percent_Identity=37.6923076923077, Blast_Score=108, Evalue=1e-24, Organism=Escherichia coli, GI1788769, Length=443, Percent_Identity=24.6049661399549, Blast_Score=94, Evalue=3e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018113 - InterPro: IPR004719 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR011296 [H]
Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 72373; Mature: 72241
Theoretical pI: Translated: 6.38; Mature: 6.38
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVKEIEKISVVKGTFTNAG CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHEEECCCCCCC QFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNALQQVMTMLAEIFTPIIPAI EEEEEECCCCCEEECCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH IVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVWNTIVRVSPFWSGVNHFLWLP HHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCHHHHHEEECHHHCCCCCEEECC GEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQLLNAYAVAGTPAAEIAKNWVWD HHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHHHHHCHHHHHHEEECCCCHHHHHHHHHHH FGFFIINRIGYQAQVIPALLAGLSLAYLEIFWRKRIPEVVSMIFVPFLSLIPALILAHTV HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGALYAPLVITGLHHMTNAIDTQLIADTA HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TRTTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAEISLPAAISAYLGVTEPALFGVNVK HCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCHHCCCCHH YVYPFVAGMIGSGIAGLLSTSFNVQANSIGVGGLPGFMAINVKYMIPFFICMAVAIVVPM HHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH FLTFFFRKSHIMTKTEDEAKLPETPVSEAPAATAPHKTMQGTVITLTSPLTGEVKALSEA HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHH VDPVFAQGVMGQGALLQPTEGVLVAPCDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTV HHHHHHHCCCCCCCEECCCCCEEEEECCCCEEEEECCCCEEEEEEHHHHHHHHHCCCCEE NLDGQGFEALVKQGDQVKAGQTLIQFDIAAISEAGYATETPLVVTNQDAFTVTVEGNLPH ECCCCCHHHHHCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCC QIKANDKLAVAMKK EECCCCEEEEEECC >Mature Secondary Structure GKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVKEIEKISVVKGTFTNAG CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHEEECCCCCCC QFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNALQQVMTMLAEIFTPIIPAI EEEEEECCCCCEEECCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH IVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVWNTIVRVSPFWSGVNHFLWLP HHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCHHHHHEEECHHHCCCCCEEECC GEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQLLNAYAVAGTPAAEIAKNWVWD HHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHHHHHCHHHHHHEEECCCCHHHHHHHHHHH FGFFIINRIGYQAQVIPALLAGLSLAYLEIFWRKRIPEVVSMIFVPFLSLIPALILAHTV HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGALYAPLVITGLHHMTNAIDTQLIADTA HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TRTTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAEISLPAAISAYLGVTEPALFGVNVK HCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCHHCCCCHH YVYPFVAGMIGSGIAGLLSTSFNVQANSIGVGGLPGFMAINVKYMIPFFICMAVAIVVPM HHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH FLTFFFRKSHIMTKTEDEAKLPETPVSEAPAATAPHKTMQGTVITLTSPLTGEVKALSEA HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHH VDPVFAQGVMGQGALLQPTEGVLVAPCDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTV HHHHHHHCCCCCCCEECCCCCEEEEECCCCEEEEECCCCEEEEEEHHHHHHHHHCCCCEE NLDGQGFEALVKQGDQVKAGQTLIQFDIAAISEAGYATETPLVVTNQDAFTVTVEGNLPH ECCCCCHHHHHCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCC QIKANDKLAVAMKK EECCCCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7608078; 7610040; 9278503 [H]