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The map label for this gene is licC [H]

Identifier: 19746933

GI number: 19746933

Start: 1763555

End: 1764859

Strand: Reverse

Name: licC [H]

Synonym: spyM18_2111

Alternate gene names: 19746933

Gene position: 1764859-1763555 (Counterclockwise)

Preceding gene: 19746934

Following gene: 19746932

Centisome position: 93.13

GC content: 42.61

Gene sequence:

>1305_bases
ATGGCAAAAATGAATATGCAAAACATCATCATGCCAATCATGACATTTGTGAATATGCGCGGCATCATTGCCTTAAAAGA
CGGTATGTTAGCCATTTTACCTTTGACCGTTGTGGGGAGTCTTTTCCTGATTGCTGGTCAGATTCCTTTTCAAGGGATTA
ATGATGCCATTGCCGGTGTGTTTGGTGCCGACTGGACAGAACCCTTTATGCAGGTTTACCATGGAACGTTTGCTATTATG
GGCTTGATTTCCTGCTTTGCGATTGGTTATTCTTATGCTAAAAACTCAGGTGTTGAACCTCTCCCTTCAGGGGTTCTATC
CTTATCAGCTTTCTTTATTCTATTGAGATCATCTTATGTTCCAGCAGAAGGCGAACCTATCGGTGATGCTATTAGCAAGG
CTTGGTTTGGTGGGCAAGGGATTATTGGTGCTATTGTGATTGGTTTAACGGTAGGTGCTATTTATACAGCATTTATCCGT
CGCCACATTGTCATCAAAATGCCAGAGCAAGTGCCACAAGCCATTGCCAAACAGTTTGAAGCTATGATTCCAGCCTTTGT
GATTTTTACCTTGTCAATGCTTGTGTACATTATTGCCAAGTCAGTGACAGGTGGTGGCACCTTTATTGAAATGATTTATG
ATGTCATTCAGGTACCGCTGCAAGGGTTAACGGGTTCTCTTTATGGCGCACTAGGTATTGCCTTCTTTATTTCCTTTCTT
TGGTGGTTTGGCGTGCATGGGCAATCTGTGGTCAATGGAATTGTCACTGCTCTTCTCTTATCAAATCTAGATGCCAATAA
GGCCTTGATGGCAGCAGGTGAGTTATCCCTAGACAAGGGTGCCCATATTGTAACCCAACAATTTTTAGACTCTTTCTTGA
TTCTATCAGGTTCTGGCATTACCTTTGGTTTAGTGGTAGCTATGATCTTTGCGGCTAAATCCAAACAATACAAGGCTTTA
GGTAAGGTTGCAGCCTTCCCAGCCCTCTTTAATGTTAATGAACCTGTCGTCTTTGGTTTTCCAATTGTGATGAATCCAGT
CATGTTCTTGCCATTTATCTTGGTTCCTGTCTTGGCAGCTCTCACAGTTTATGGCGCCATTGCTATTGGTTTCATGCAGC
CCTTTGCAGGAGTGACCCTTCCGTGGTCAACACCAGCCATTATCTCAGGGTTCATGGTTGGTGGCTGGCAAGGAGCTATT
GTGCAAATTCTTATACTCATCATGTCAACGTTGGTGTACTTCCCATTCTTTAAAATTCAAGATAATATGGCTTATCAAAA
TGAACAAGCTAGTGAAGAGTCATGA

Upstream 100 bases:

>100_bases
TATCCCCATTGCAGTTATCCCAATGGCTGATTATGGAATGTTAGACGGCAACAAGGTGCTTGATTTAGCCCTTAGCCTTG
TTAAAGAATAGGAGTCAATC

Downstream 100 bases:

>100_bases
TTTAGCGTCCACACAAATTCTTGAGACCATCTCCAGTTAGAGGTGGTTTTTTAGAAAAAGAAGAGCTACTTATCAGGCCT
ATATTGCACAATAGTGCAAA

Product: PTS system, cellobiose-specific IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MAKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLIAGQIPFQGINDAIAGVFGADWTEPFMQVYHGTFAIM
GLISCFAIGYSYAKNSGVEPLPSGVLSLSAFFILLRSSYVPAEGEPIGDAISKAWFGGQGIIGAIVIGLTVGAIYTAFIR
RHIVIKMPEQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQVPLQGLTGSLYGALGIAFFISFL
WWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELSLDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKAL
GKVAAFPALFNVNEPVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFMVGGWQGAI
VQILILIMSTLVYFPFFKIQDNMAYQNEQASEES

Sequences:

>Translated_434_residues
MAKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLIAGQIPFQGINDAIAGVFGADWTEPFMQVYHGTFAIM
GLISCFAIGYSYAKNSGVEPLPSGVLSLSAFFILLRSSYVPAEGEPIGDAISKAWFGGQGIIGAIVIGLTVGAIYTAFIR
RHIVIKMPEQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQVPLQGLTGSLYGALGIAFFISFL
WWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELSLDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKAL
GKVAAFPALFNVNEPVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFMVGGWQGAI
VQILILIMSTLVYFPFFKIQDNMAYQNEQASEES
>Mature_433_residues
AKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLIAGQIPFQGINDAIAGVFGADWTEPFMQVYHGTFAIMG
LISCFAIGYSYAKNSGVEPLPSGVLSLSAFFILLRSSYVPAEGEPIGDAISKAWFGGQGIIGAIVIGLTVGAIYTAFIRR
HIVIKMPEQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQVPLQGLTGSLYGALGIAFFISFLW
WFGVHGQSVVNGIVTALLLSNLDANKALMAAGELSLDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALG
KVAAFPALFNVNEPVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFMVGGWQGAIV
QILILIMSTLVYFPFFKIQDNMAYQNEQASEES

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=445, Percent_Identity=33.9325842696629, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46567; Mature: 46436

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHCCCCCCCCC
>Mature Secondary Structure 
AKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLIAGQIPFQGINDAIAGV
CCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLPSGVLSLSAFFILLRSSYV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
PAEGEPIGDAISKAWFGGQGIIGAIVIGLTVGAIYTAFIRRHIVIKMPEQVPQAIAKQFE
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
AMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQVPLQGLTGSLYGALGIAFFISFL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
WWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELSLDKGAHIVTQQFLDSFLILSGSGI
HHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCH
TFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNEPVVFGFPIVMNPVMFLPFILVPVLAA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
LTVYGAIAIGFMQPFAGVTLPWSTPAIISGFMVGGWQGAIVQILILIMSTLVYFPFFKIQ
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEE
DNMAYQNEQASEES
CCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]