| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
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The map label for this gene is ptsG [H]
Identifier: 19746889
GI number: 19746889
Start: 1712675
End: 1714861
Strand: Reverse
Name: ptsG [H]
Synonym: spyM18_2050
Alternate gene names: 19746889
Gene position: 1714861-1712675 (Counterclockwise)
Preceding gene: 19746890
Following gene: 19746888
Centisome position: 90.49
GC content: 44.35
Gene sequence:
>2187_bases ATGAAAACATCATTCAAACAACTGTTTCGTTTCGAATTTTGGCAAAAATTTGGGAAATGTCTTATGGTCGTTATTGCTGT CATGCCAGCGGCTGGTTTAATGATCAGTATCGGAAACTCTATTCCAATGATTAACCACGACTCAGCATTTTTGGCATCTC TAGGCAACATTATCGCTCAAATTGGTTGGGCTGTTATTGTAAACCTTCATTTGCTATTTGCCTTGGCCATTGGTGGTAGT TGGGCTAAAGAAAGAGCTGGAGGGGCCTTTGCCTCAGGTCTTGCTTTTGTCTTGATCAATCGGATAACAGGCGCTTTTTA TGGCGTGTCTAGTGCTATGCTAGCTGATCCAGAAGCAAAAATCACAAGCTTCCTTGGCACTCAAATGATCGTTAAAGATT ATTTCACCAGTGTCTTGGAATCTCCAGCTTTAAACACAGGGGTTTTTGTTGGGATTATTGCAGGGTTCGTAGGAGCAACG GCCTATAACAAATACTATAATTACCGTAAACTTCCTGAAGTTTTGACCTTCTTTAATGGGAAGCGTTTTGTACCATTTGT CGTTATTTTACGTTCTATTTTTGTAGCCCTTATTTTGGTTGTTGTTTGGCCGGTGATCCAGTCTGGGATTAACAGTTTTG GGATGTGGATTGCCTCTTCACAAGATTCAGCTCCAATCCTAGCCCCATTCCTATATGGTACCTTGGAACGTCTCTTGTTG CCATTTGGTCTTCACCATATGTTGACGATCCCAATGAACTATACAGCTCTTGGTGGAACTTATGAGGTCATGACAGGTGC AGCAGCGGGGACAAAAGTATTTGGTCAAGACCCTTTGTGGCTTGCTTGGGTAACTGACCTTGTTCACCTTAAAGGATCAG ACGCTTCAGCCTATAGTCACTTAATGGATAGCGTGACTCCAGCTCGCTTTAAGGTAGGACAAATGATTGGAGCTACCGGA ACATTGATGGGGATTGCCTTAGCCATGTACCGTAATGTGGATGCCGATAAAAAACACACATACAAAATGATGTTCATCTC AGCAGCGGCAGCGGTCTTTTTGACAGGGGTAACTGAGCCACTTGAGTACCTATTTATGTTTGCAGCAATGCCACTTTACA TCGTCTATGCCCTTGTTCAAGGAGCTTCATTTGCCATGGCAGACCTTGTGAATCTCCGTGTTCACTCATTTGGAAATATA GAGCTACTAACCCGCACCCCTATGGCCCTTAAAGCAGGTCTAGGCATGGATGTGATTAACTTTGTTTGGGTTTCTATCCT CTTTGCAGTTATCATGTACTTTATTGCAGATATGATGATTAAGAAAATGCATCTCGCGACAGCTGGCCGTTTAGGCAACT ACGATGCCGATATACTGGGTGACCGTAACACTCAAGCAAGACCTACCCAAGTAGCAGATAGCAACTCTCAAGTCGTACAA ATCATTAATCTCCTTGGTGGGGCAGGCAATATTGATGATGTTGATGCTTGTATGACGCGCTTACGAGTGACGGTCAAAGA TCCCGCTAAAGTTGGCGCTGAGGACGATTGGAAAAAAGCTGACGCTATGGGCTTGATCCAAAAAGGCAACGGCGTTCAAG CGGTCTATGGCCCTAAAGCAGATGTTTTGAAATCAGATATTCAAGATCTGCTGGACTCAGGTGCTCTTATTCCAGAAGTC AATATGTCACAGCTCACTAGCAAACCGACTCCCGCAAAAGATTTTAAACACGTGACAGAAGAAGTGCTATCAGTGGCAGA CGGGATGGTTCTCCCAATCACAGGTGTGAAAGACCAGGTGTTTGCGGCTAAGATGATGGGAGATGGGTTTGCGGTTGAAC CAACAAATGGCAATATCTATGCACCCGTAGCTGGCCTTGTGACCAGTGTCTTTCCGACCAAGCATGCCTTTGGTTTACTG ACAGATAATGGTCTTGAAGTGCTGGTGCACGTGGGACTTGATACCGTCGCCTTAAATGGTGTGCCTTTTTCAGTCAAAGT CTCAGAAGGACAACGGGTTCATGCAGGTGACCTATTAGTCGTAGCAGACCTTGCTGCTATTAAATCAGCAGAGCGTGAAA CAACCATTGTTGTTGCTTTTACCAACACAGCAGAGATCCAAGATGTGACCTTGACTTCTTTAGGCAATCAACCTGCTAAG ACTAAAGTAGCCACCGTAGAACTTTAA
Upstream 100 bases:
>100_bases TGCAAGCGATTGCATCACTGAGTTGTAGTCTATATCATTGTGTCACAAAAGCGCCTTAAGGGCAGCTATGGCTAAAAGGG GATAATAAAGGAGAGATAGA
Downstream 100 bases:
>100_bases CAAAACATCACGAGATAGTGATAGGTAATAGCCATAGCTGGTTTAGGCCCTATGGCTCTTCTTGTCTTATAAAGGAGGAT TAATGACCAAGGTATTAACA
Product: PTS system, glucose-specific IIABC component
Products: NA
Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]
Number of amino acids: Translated: 728; Mature: 728
Protein sequence:
>728_residues MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGS WAKERAGGAFASGLAFVLINRITGAFYGVSSAMLADPEAKITSFLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATG TLMGIALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI ELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQARPTQVADSNSQVVQ IINLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKADAMGLIQKGNGVQAVYGPKADVLKSDIQDLLDSGALIPEV NMSQLTSKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVAGLVTSVFPTKHAFGLL TDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAK TKVATVEL
Sequences:
>Translated_728_residues MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGS WAKERAGGAFASGLAFVLINRITGAFYGVSSAMLADPEAKITSFLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATG TLMGIALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI ELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQARPTQVADSNSQVVQ IINLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKADAMGLIQKGNGVQAVYGPKADVLKSDIQDLLDSGALIPEV NMSQLTSKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVAGLVTSVFPTKHAFGLL TDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAK TKVATVEL >Mature_728_residues MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGS WAKERAGGAFASGLAFVLINRITGAFYGVSSAMLADPEAKITSFLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATG TLMGIALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI ELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQARPTQVADSNSQVVQ IINLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKADAMGLIQKGNGVQAVYGPKADVLKSDIQDLLDSGALIPEV NMSQLTSKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVAGLVTSVFPTKHAFGLL TDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAK TKVATVEL
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1786894, Length=719, Percent_Identity=31.5716272600835, Blast_Score=255, Evalue=9e-69, Organism=Escherichia coli, GI1787343, Length=542, Percent_Identity=30.6273062730627, Blast_Score=215, Evalue=9e-57, Organism=Escherichia coli, GI1787908, Length=555, Percent_Identity=30.0900900900901, Blast_Score=214, Evalue=2e-56, Organism=Escherichia coli, GI1790159, Length=165, Percent_Identity=35.7575757575758, Blast_Score=105, Evalue=1e-23, Organism=Escherichia coli, GI1788757, Length=131, Percent_Identity=38.9312977099237, Blast_Score=102, Evalue=1e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR011300 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 78265; Mature: 78265
Theoretical pI: Translated: 6.85; Mature: 6.85
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 4.4 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQ CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCHHHHHHHHHHHHH IGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRITGAFYGVSSAMLADPEAK HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH ITSFLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTFFNG HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC KRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEECCCCCCCHHHHHHHHHHHHHHH PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSH HHCCHHHEEECCCEEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH LMDSVTPARFKVGQMIGATGTLMGIALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEP HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH LEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMDVIN HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHH FVWVSILFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQARPTQVADSNSQVVQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHH IINLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKADAMGLIQKGNGVQAVYGPKA HHHHHCCCCCCCHHHHHHHHHEEEECCHHHCCCCCCHHHHHHHHHEECCCCEEEEECCCH DVLKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQV HHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHH FAAKMMGDGFAVEPTNGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNG HHHHHCCCCEEEECCCCCEEECHHHHHHHHCCCHHHEEEEECCCCEEEEEECCCEEEECC VPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAK CCEEEEECCCCEEECCCEEEEHHHHHHHCCCCCEEEEEEEECCCCCCEEEHHHCCCCCCC TKVATVEL CEEEEEEC >Mature Secondary Structure MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQ CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCHHHHHHHHHHHHH IGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRITGAFYGVSSAMLADPEAK HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH ITSFLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTFFNG HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC KRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEECCCCCCCHHHHHHHHHHHHHHH PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSH HHCCHHHEEECCCEEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH LMDSVTPARFKVGQMIGATGTLMGIALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEP HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH LEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMDVIN HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHH FVWVSILFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQARPTQVADSNSQVVQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHH IINLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKADAMGLIQKGNGVQAVYGPKA HHHHHCCCCCCCHHHHHHHHHEEEECCHHHCCCCCCHHHHHHHHHEECCCCEEEEECCCH DVLKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQV HHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHH FAAKMMGDGFAVEPTNGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNG HHHHHCCCCEEEECCCCCEEECHHHHHHHHCCCHHHEEEEECCCCEEEEEECCCEEEECC VPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAK CCEEEEECCCCEEECCCEEEEHHHHHHHCCCCCEEEEEEEECCCCCCEEEHHHCCCCCCC TKVATVEL CEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11463916; 7934910 [H]