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The map label for this gene is polC [H]

Identifier: 19746791

GI number: 19746791

Start: 1602172

End: 1602759

Strand: Reverse

Name: polC [H]

Synonym: spyM18_1928

Alternate gene names: 19746791

Gene position: 1602759-1602172 (Counterclockwise)

Preceding gene: 19746792

Following gene: 19746790

Centisome position: 84.58

GC content: 39.29

Gene sequence:

>588_bases
ATGAAACACTTAGATACTTATATTGCCTTTGATTTAGAATTTAACACTGTCAATGACGTTAGTCATGTCATTCAAGTATC
AGCAGTCAAATATGACCACCATAAAGAAGTTGACAGCTTTGACACCTATGTTTACACAGATGTTCCCTTACAGAGCTTTA
TCAATGGCCTAACAGGAATCACATCTGACAAGATTGCTGCGGCACCAAAAGTAGAGGAGGTTATGGCTGCGTTTAAAAAT
TTTGTGGGAGAGTTACCACTGATTGGTTATAATGCTCAAAAATCTGACCTGCCTATTCTAGCTGAAAATGGCTTAGATTT
AAGGGACCAATACCAGATTGACCTCTTTGATGAAGCTTACGATAGACGTAGCGCAGACTTAAATGGGATTGCTAACCTTC
GTCTGCAAACAGTGGCAACCTTTTTAGGCATTAAGGGTCGAGGTCATAATAGCTTAGAAGATGCCAGAATGACAGCAGCA
ATCTATAAGTCTTTTTTAGAAACAGATACAAACAAAGCATATCTCAGCCAGCAAGAAGAGGTAACCACAGATAACCCTTT
CGCAGCTTTGGGAGACTTTTTTGACTAA

Upstream 100 bases:

>100_bases
GGCTGAAGTTGGCCCTAAAAAAGGCTTTTTCACCCGCTTGTTTGCGAAATAATCACAAAAAATGACGAAGGCCCTATCAG
GGTCTTTTTTGGAGGAAAAC

Downstream 100 bases:

>100_bases
GGGCTCTGCTATTTCTAAAAAATAACAAAAATTCCTAGGGTTAGCTCTTGCTTGTAACGCTAGGTCATGTGATAAGATAG
GGGCATATCAAGAGGGAGTC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYVYTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKN
FVGELPLIGYNAQKSDLPILAENGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD

Sequences:

>Translated_195_residues
MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYVYTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKN
FVGELPLIGYNAQKSDLPILAENGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD
>Mature_195_residues
MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYVYTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKN
FVGELPLIGYNAQKSDLPILAENGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 21829; Mature: 21829

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYVYTDVPLQSFINGLTGI
CCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCC
TSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAENGLDLRDQYQIDLFDEAY
CCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCEEECCCCCCCCCEEEEEHHHHH
DRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAAIYKSFLETDTNKAYLSQQEE
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
VTTDNPFAALGDFFD
CCCCCCHHHHCCCCC
>Mature Secondary Structure
MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYVYTDVPLQSFINGLTGI
CCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCC
TSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAENGLDLRDQYQIDLFDEAY
CCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCEEECCCCCCCCCEEEEEHHHHH
DRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAAIYKSFLETDTNKAYLSQQEE
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
VTTDNPFAALGDFFD
CCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]