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The map label for this gene is mta [H]

Identifier: 19746790

GI number: 19746790

Start: 1601282

End: 1602019

Strand: Reverse

Name: mta [H]

Synonym: spyM18_1927

Alternate gene names: 19746790

Gene position: 1602019-1601282 (Counterclockwise)

Preceding gene: 19746791

Following gene: 19746787

Centisome position: 84.54

GC content: 39.7

Gene sequence:

>738_bases
ATGTCTCAATTCTATTCGACTGGAGAATTGGCCAACTTAGCTGGCGTTTCTATTCGAACTGTCCAATACTATGACCAACG
TGGGATTTTGATTCCGACAGCTTTGACAGAAGGTGGACGGCGACTCTATACGGATTCTGATTTAGAACAATTACGCATGA
TTTGCTTTCTGCGCGATTTGGGATTTTCCATTGAGCAGATTCGCAAAGTCTTAGCAGAGGAAAATGCAGCCCAGGTGCTG
GAATTGCTTCTAGTTGATCATATTGCGACTGCCAAGGAAGACTTGGCCGCAAAAGAGCAACAAGTTGACATAGCTGTCAA
GATACTTGACAGACTTCGAAAACAAGACCCCCAGTCACTAGATTTTCTGATGGACATTTCGCTTAGCATGAAAAATCAAA
AAGCTTGGAAAAAATTACAATGGAAGATGGGTATCAGTATATTTTTAGCCATTGTTTCATATGTAGGACTTATTTTACTA
TCTAGTTATCTGCAAAAATTTTGGTTAGTTTATGTTGCTATGGGACTATTTCTACCAGGTTTCAGTTGGTTGGTAATTTA
TTTTAGGAAGCAATTTATTTATCTCTGTCCCCATTGTCATCAGAAATTTGAACCTAGCTTTAATGAATTTGCCCTTGCAG
GCCATACACCACGAACCAGAAAGTTAACCTGCTCCCATTGCCATCAAAAATCGTATTGCTTGGAACTGGCAAAAGAGGAC
ACTGTCTCAAGAAGATAA

Upstream 100 bases:

>100_bases
TGTAACGCTAGGTCATGTGATAAGATAGGGGCATATCAAGAGGGAGTCGAGTGCACACGAATCGTTTTTGATCACTAAAT
GATAGAAAGAAGGTGTGGAA

Downstream 100 bases:

>100_bases
GCACTAACTCATAAAAAAACTAGCCTGAGATCCTTCTCAAGCTAGTTTTTGTTTTTTTAGAATGGTAATTTACCAGCAAA
AGCGCCTAATGTTTTCTTAG

Product: transcriptional activator

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYTDSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVL
ELLLVDHIATAKEDLAAKEQQVDIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
SSYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPRTRKLTCSHCHQKSYCLELAKED
TVSRR

Sequences:

>Translated_245_residues
MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYTDSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVL
ELLLVDHIATAKEDLAAKEQQVDIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
SSYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPRTRKLTCSHCHQKSYCLELAKED
TVSRR
>Mature_244_residues
SQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYTDSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLE
LLLVDHIATAKEDLAAKEQQVDIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILLS
SYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPRTRKLTCSHCHQKSYCLELAKEDT
VSRR

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=69, Percent_Identity=46.3768115942029, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 28310; Mature: 28179

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYTDSDLEQLRMICFLRDL
CCCCCCCCCHHHHCCCEEEEEEEECCCCEEEEHHHCCCCCEECCCCCHHHHHHHHHHHHH
GFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQVDIAVKILDRLRKQDPQSL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILLSSYLQKFWLVYVAMGLFLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPRTRKLTCSHCHQKSYCLELAKED
HHHHHHHHHHHHHHHCHHHHHHCCCCHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
TVSRR
CCCCC
>Mature Secondary Structure 
SQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYTDSDLEQLRMICFLRDL
CCCCCCCCHHHHCCCEEEEEEEECCCCEEEEHHHCCCCCEECCCCCHHHHHHHHHHHHH
GFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQVDIAVKILDRLRKQDPQSL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILLSSYLQKFWLVYVAMGLFLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPRTRKLTCSHCHQKSYCLELAKED
HHHHHHHHHHHHHHHCHHHHHHCCCCHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
TVSRR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]