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The map label for this gene is comEB [H]

Identifier: 19746757

GI number: 19746757

Start: 1566655

End: 1567116

Strand: Reverse

Name: comEB [H]

Synonym: spyM18_1888

Alternate gene names: 19746757

Gene position: 1567116-1566655 (Counterclockwise)

Preceding gene: 19746758

Following gene: 19746756

Centisome position: 82.7

GC content: 43.72

Gene sequence:

>462_bases
ATGACAAATCGTTTATCATGGCAAGACTATTTTATGGCCAATGCAGAGCTGATTTCCAAGCGCTCTACCTGTGATCGCGC
CTTTGTGGGAGCTGTTTTGGTAAAGGATAACCGCATTATTGCCACAGGTTACAATGGCGGAGTTTCTGCTACGGATAACT
GCAACGAAGCGGGTCATTATATGGAAGACGGACATTGCATCAGGACAGTTCATGCTGAAATGAATGCTTTGATTCAATGT
GCGAAAGAAGGAATTTCAACGGACGGAACTGAAATTTACGTGACTCATTTTCCTTGTATTAACTGCACTAAGGCGCTTTT
GCAGGCGGGGATTACAAAGATTACCTATAAAGCACATTACCGTCCGCACCCCTTTGCCATTGAACTGATGGAGAAAAAAG
GGGTTGCCTATGTGCAACATGATGTGCCTCAAATTGTTTTAGGAGGCGATAAGGAACAATAG

Upstream 100 bases:

>100_bases
TTGGTTATCACAAAAACTGGTTGTCAAGTCTTGACCTTGGCACCCAAAGAATTAATTGTATTGTAAAAGAATGGTTCAGG
AAAGGATTAGGGGAGAAGCA

Downstream 100 bases:

>100_bases
AAAGTGTACCTAAAAGGACGGTCATAAAAGATTTGAGCCAAGGCCACTTTTGTGGTAAAATGAAGTGATAAATATTTTAG
TAAGAGGTAATAATAATGAT

Product: late competence protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGYNGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQC
AKEGISTDGTEIYVTHFPCINCTKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ

Sequences:

>Translated_153_residues
MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGYNGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQC
AKEGISTDGTEIYVTHFPCINCTKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ
>Mature_152_residues
TNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGYNGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCA
KEGISTDGTEIYVTHFPCINCTKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742821, Length=117, Percent_Identity=35.042735042735, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI61742819, Length=117, Percent_Identity=35.042735042735, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321938, Length=153, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667298, Length=158, Percent_Identity=35.4430379746835, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667302, Length=158, Percent_Identity=35.4430379746835, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 16967; Mature: 16835

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGYNGGVSATDNCNEAGHY
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEEEEECCEEEEECCCCCCCCCCCCCCCCCC
MEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINCTKALLQAGITKITYKAHY
CCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEECC
RPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ
CCCCEEEEEECCCCCEEEECCCCEEEECCCCCC
>Mature Secondary Structure 
TNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGYNGGVSATDNCNEAGHY
CCCCCCHHHHHHHHHHHHCCCCCCHHHHEEEEEECCEEEEECCCCCCCCCCCCCCCCCC
MEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINCTKALLQAGITKITYKAHY
CCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEECC
RPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ
CCCCEEEEEECCCCCEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]