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The map label for this gene is alr [H]

Identifier: 19746744

GI number: 19746744

Start: 1549784

End: 1550884

Strand: Reverse

Name: alr [H]

Synonym: spyM18_1871

Alternate gene names: 19746744

Gene position: 1550884-1549784 (Counterclockwise)

Preceding gene: 19746745

Following gene: 19746743

Centisome position: 81.84

GC content: 41.05

Gene sequence:

>1101_bases
ATGATTTCAAGTTTCCATCGCCCAACAGTTGCAAGGGTCAACTTACAAGCTATTAAGGAGAATGTTGCCAGTGTTCAAAA
GCATATTCCACTAGGGGTAAAAACGTATGCAGTTGTCAAGGCTGATGCTTATGGTCATGGTGCTGTCCAGGTGTCAAAAG
CACTCCTACCTCAAGTGGATGGGTACTGTGTGTCAAATCTTGATGAGGCTTTGCAATTACGTCAAGCAGGTATTGATAAA
GAGATTTTAATTCTTGGGGTTTTGCTGCCAAATGAGCTAAAGTTGGCGATTACTCGCCAGGTTACAGTGACAGTGGCTAG
TTTAGAGTGGCTGGCGATGGCCAAGCAAGAATGGCCAGATTTGAAAGGGCTTAAGGTCCATATCAAAATTGATTCAGGCA
TGGGACGAATCGGGCTTCGCTCAGTAACAGAAGTTGATAATCTGATTGCTGGCTTGAAGAGCATGGGTGCTGATGTAGAA
GGTATTTTTACTCATTTTGCCACAGCTGATGAGGCAGATGATACTAAATTTAACCAGCAGTTACAGTTTTTTAAAAAGCT
AATAGCTGGACTTGAGGATAAGCCTCGTTTAGTACATGCTAGTAATTCAGCCACAAGTATCTGGCATAGTGATACCATTT
TTAATGCTGTTCGTTTAGGAATTGTCAGTTATGGTTTGAATCCAAGTGGTTCTGATCTAAGCTTACCATTTCCACTGCAA
GAGGCTTTATCTCTAGAATCTAGCTTAGTGCATGTCAAGATGATTTCAGCTGGTGATACAGTCGGTTATGGAGCTACTTA
TACTGCCAAAAAGTCTGAATATGTAGGGACCGTCCCAATCGGTTATGCAGATGGCTGGACCAGGAACATGCAAGGCTTTT
CGGTGTTAGTTGATGGACAATTCTGTGAAATTATAGGGCGTGTATCGATGGATCAACTGACCATACGACTTTCCAAAGCA
TATCCTTTAGGAACAAAAGTCACTTTGATTGGCAGCAATCAGCAAAAAAATATTTCTACAACAGATATCGCAAATTACCG
TAATACAATCAATTATGAAGTTCTATGCCTTTTAAGTGACCGTATTCCTCGGATATATTAA

Upstream 100 bases:

>100_bases
GTCCCATTCTGACAAAATCTCCGTTTAAAGGAAATAGTTTTATTAGCATCTCACATAGTGGCAATTATGTACAGGCTAGT
GTTATTTTGGAGGATAAAAA

Downstream 100 bases:

>100_bases
GAAAATCATGTAAAAATAATTGCATTGTGCTTATCTTTAATGTTATAATAAAGTGAGGACATTAGAAAGAAGTGACTAAT
TAATATATGAATAAAAACAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDK
EILILGVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPDLKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVE
GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQ
EALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLSKA
YPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLSDRIPRIY

Sequences:

>Translated_366_residues
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDK
EILILGVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPDLKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVE
GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQ
EALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLSKA
YPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLSDRIPRIY
>Mature_366_residues
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDK
EILILGVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPDLKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVE
GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQ
EALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLSKA
YPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLSDRIPRIY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=363, Percent_Identity=34.435261707989, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1790487, Length=365, Percent_Identity=31.7808219178082, Blast_Score=151, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39965; Mature: 39965

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVD
CCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCC
GYCVSNLDEALQLRQAGIDKEILILGVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPD
CHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEEEEEEHHHHHHHHHHHCCC
LKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVEGIFTHFATADEADDTKFNQQ
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHH
LQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQ
HHHHHHHHHCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
EALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQ
HHHHHHHCEEEEEEEECCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCEEEECCH
FCEIIGRVSMDQLTIRLSKAYPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLSD
HHHHHHCCCHHHEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEECC
RIPRIY
CCCCCC
>Mature Secondary Structure
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVD
CCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCC
GYCVSNLDEALQLRQAGIDKEILILGVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPD
CHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEEEEEEHHHHHHHHHHHCCC
LKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVEGIFTHFATADEADDTKFNQQ
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHH
LQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQ
HHHHHHHHHCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
EALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQ
HHHHHHHCEEEEEEEECCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCEEEECCH
FCEIIGRVSMDQLTIRLSKAYPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLSD
HHHHHHCCCHHHEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEECC
RIPRIY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]