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The map label for this gene is isp [H]

Identifier: 19746743

GI number: 19746743

Start: 1548150

End: 1549697

Strand: Reverse

Name: isp [H]

Synonym: spyM18_1870

Alternate gene names: 19746743

Gene position: 1549697-1548150 (Counterclockwise)

Preceding gene: 19746744

Following gene: 19746742

Centisome position: 81.78

GC content: 40.89

Gene sequence:

>1548_bases
ATGAATAAAAACAAACTATTAAGAGTTGCCATGCTACTAAGTCTCTTAGCCCCGACAGCAGAAAGCATGACAGTGTTGGC
TCAAGATGTAATGCTTGAGACGCATAAAGCAACTACAAATGAAACCAGTGATTCTTCTTCAAAAGAGGAAAATAATAAAA
ATGCAGCACCTACAACATCAGATAAAACTGACCAAGGTCCCCTTGATGCTTCTGCAGAAACAAACTCTAATAGTCTTGTT
AACGCGGATGATAAAAAAAGAAGCGATTCTAGTCAGTCTGTTGTAGGTTCTTCGGACAACAAGGCAGAAGCAGAAAACCA
GGTAGATGATAAATCAACTGACCATTCGAAACCAACTGACCATTCGAAACCAACTGACCATTCGAAACCAACTGACCAGC
CAAAACCGACTGATCAGCCCAAACCATCACCATCTAAAGTTGATACGGCACCTGCTTCTTCATTGTCGAGACAGTTGCCA
GAGGTAAGAACTCCTATTCAGTCGTTGTCACCTTACGTATCAGATTTAGATTTGAGTGAGATAGATATCCCTTCTGTCAA
CACATACGCGGCATATGTAGAGCATTGGAGTGGTAAAAATGCCTATACCCACCATCTTTTATCTCGCCGTTATGGTATTA
AAGCTGACCAGATTGATAGTTACTTAAAATCAACAGGCATTGCCTATGACAGCACACGTATTAATGGTGAGAAGCTATTG
CAATGGGAAAAGAAAAGTGGGCTGGATGTTCGAGCTATCGTAGCTATTGCGATGTCTGAGAGTTCTTTAGGAACTCAAGG
GATTGCGACTTTGCTTGGAGCTAATATGTTTGGCTATGCAGCTTTTGATCTAGATCCGACTCAAGCAAGTAAGTTTAATG
ATGATAGTGCTATTGTCAAAATGACACAAGATACCATTATTAAAAACAAAAATAGCAATTTTGCACTTCAAGATTTAAAA
GCGGCTAAGTTTTCACGAGGTCAATTAAACTTTGCAAGTGACGGGGGTGTTTATTTTACTGATACTACTGGTAGTGGTAA
ACGTCGCGCACAAATTATGGAAGACCTGGATAAGTGGATTGATGACCATGGTGGCACACCAGTCATTCCAGCCGAATTGA
AAGTGCAGTCATCAGCTAGTTTTGCATCTGTGCCAGCAGGTTATAAGCTCTCTAAGAGTTATGATGTCTTGGGTTATCAA
GCTTCGAGTTATGCTTGGGGACAATGCACTTGGTATGTGTATAATCGCGCCAAAGAATTGGGGTACCAATTTGATCCTTT
TATGGGAAATGGTGGAGATTGGAAGTATAAAGCAGGGTATGCCCTGTCAAAGACTCCAAAAGTAGGTTATGCTATTTCAT
TTGCACCCGGGCAAGCAGGCGCTGATGGCACTTATGGCCACGTATCAATTGTAGAAGATGTTAGAAAAGATGGGTCTATT
CTTATTTCAGAGTCTAACTGTATCGGCTTAGGCAAGATTTCTTATCGTACCTTTACAGCTCAGCAGGCTGAACAGCTAAC
ATATGTTATTGGCAAGAGTAAAAACTAA

Upstream 100 bases:

>100_bases
CTCGGATATATTAAGAAAATCATGTAAAAATAATTGCATTGTGCTTATCTTTAATGTTATAATAAAGTGAGGACATTAGA
AAGAAGTGACTAATTAATAT

Downstream 100 bases:

>100_bases
TAACTAATGACTTTTCTTAAGGCTTAATTTTCTTAGCGGGAGTTAGGCCTTTTAAACTGTTGGTGTAACACGATAAAGTT
TCAAGTAAATAAATGATTTT

Product: immunogenic secreted protein precursor homologue

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLV
NADDKKRSDSSQSVVGSSDNKAEAENQVDDKSTDHSKPTDHSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLP
EVRTPIQSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYDSTRINGEKLL
QWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLK
AAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWIDDHGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQ
ASSYAWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGADGTYGHVSIVEDVRKDGSI
LISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN

Sequences:

>Translated_515_residues
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLV
NADDKKRSDSSQSVVGSSDNKAEAENQVDDKSTDHSKPTDHSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLP
EVRTPIQSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYDSTRINGEKLL
QWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLK
AAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWIDDHGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQ
ASSYAWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGADGTYGHVSIVEDVRKDGSI
LISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN
>Mature_515_residues
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLV
NADDKKRSDSSQSVVGSSDNKAEAENQVDDKSTDHSKPTDHSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLP
EVRTPIQSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYDSTRINGEKLL
QWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLK
AAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWIDDHGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQ
ASSYAWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGADGTYGHVSIVEDVRKDGSI
LISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN

Specific function: Peptidoglycan hydrolase involved in the splitting of the septum during cell division [H]

COG id: COG3942

COG function: function code R; Surface antigen

Gene ontology:

Cell location: Secreted. Cell surface (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase C51 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007921
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF05257 CHAP; PF01476 LysM [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 55873; Mature: 55873

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50911 CHAP ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEENNKNAAPTTS
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCC
DKTDQGPLDASAETNSNSLVNADDKKRSDSSQSVVGSSDNKAEAENQVDDKSTDHSKPTD
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
HSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRTPIQSLSPYVSDLDLSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHCCHHHHCHHHHCCCCCC
IDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYDSTRINGEKLL
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCCCCHHHHH
QWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVK
EEHHHCCCCEEEEEEEEECCCCCCHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCEEE
MTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWI
EEHHHHEECCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
DDHGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSYAWGQCTWYVYNRAKEL
HHCCCCEECCCCEEEECCCCHHCCCCCCEECCCCEEEEEECCCCCCCCEEEEEEHHHHHC
GYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGADGTYGHVSIVEDVRKDGSI
CCCCCCCCCCCCCEEEECCEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCE
LISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN
EEECCCEEEECCCEEEEECHHHHHHEEEEECCCCC
>Mature Secondary Structure
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEENNKNAAPTTS
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCC
DKTDQGPLDASAETNSNSLVNADDKKRSDSSQSVVGSSDNKAEAENQVDDKSTDHSKPTD
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
HSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRTPIQSLSPYVSDLDLSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHCCHHHHCHHHHCCCCCC
IDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYDSTRINGEKLL
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCCCCHHHHH
QWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVK
EEHHHCCCCEEEEEEEEECCCCCCHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCEEE
MTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWI
EEHHHHEECCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
DDHGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSYAWGQCTWYVYNRAKEL
HHCCCCEECCCCEEEECCCCHHCCCCCCEECCCCEEEEEECCCCCCCCEEEEEEHHHHHC
GYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGADGTYGHVSIVEDVRKDGSI
CCCCCCCCCCCCCEEEECCEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCE
LISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN
EEECCCEEEECCCEEEEECHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA