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The map label for this gene is divIVA [H]

Identifier: 19746465

GI number: 19746465

Start: 1264106

End: 1264864

Strand: Reverse

Name: divIVA [H]

Synonym: spyM18_1532

Alternate gene names: 19746465

Gene position: 1264864-1264106 (Counterclockwise)

Preceding gene: 19746466

Following gene: 19746464

Centisome position: 66.75

GC content: 36.89

Gene sequence:

>759_bases
ATGGCACTTACAACGCTAGAAATTAAAGATAAAACTTTTAAGACAAAATTCCGAGGATACTGTGAAGAAGAAGTCAATGA
ATTCCTTGATATTGTTGTTGATGATTACGAAGCTCTTGTACGTAAAAATCGTGATAACGAAGCAAGAATTAAAGATCTTG
AAGAAAAATTATCTTACTTTGATGAAATGAAAGAGTCACTTAGCCAGTCTGTAATCTTAGCTCAAGAAACAGCTGAAAAA
GTGAAAGCAACGGCTAATGCGGAAGCAACAAACTTGGTTAGTAAAGCGACTTATGATGCTCAGCATTTATTAGATGAATC
TAAAGCTAAAGCCAATCAAATGTTGCGTGATGCAACTGATGAGGCTAAGCGAGTTGCGATTGAAACAGAAGAATTAAAGC
GTCAAACACGTGTGTTCCACCAACGTTTGATCTCATCTATTGAGTCACAATTAAGCTTATCAAATTCACCTGAATGGGAT
GAACTGCTACAACCGACTGCAATCTATCTTCAAAATTCTGACGATGCTTTTAAGGAAGTCGTGAAGACCGTTCTTAATGA
AGACATTCCTGAATCTGATGATAGTGCCTCTTTTGATGCAACACGTCAGTTTACTCCAGAAGAGTTAGAAGAATTGCAAC
GTCGTGTTGATGAAAGCAATAAGGAGTTAGAGGCTTACCAACTTGACTCTCAATCTGATTCTACGACTGAGCCAGAGGTA
AATCTCAGTGAAACACAAACGTTTAAATTAAATATCTAA

Upstream 100 bases:

>100_bases
AGGTCACGGACGTTTTACTCTTTTAGCAGATAATGGAGTGACCAAACATGGCAAACAAAAAATAACACTAAGTAAAATGA
TACATAAATAAGGAGATACA

Downstream 100 bases:

>100_bases
ATAAAGAAAAACAAGATGATTTGCTTATAATCACAGCAAGCGGGAGATGATGAGAGTCTCGTATTCCCTAAGTATTATCA
TTATCATTTTCTAAAATTTT

Product: cell-division initiation protein

Products: NA

Alternate protein names: Cell division initiation protein divIVA; Minicell-associated protein divIVA [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNRDNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEK
VKATANAEATNLVSKATYDAQHLLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDESNKELEAYQLDSQSDSTTEPEV
NLSETQTFKLNI

Sequences:

>Translated_252_residues
MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNRDNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEK
VKATANAEATNLVSKATYDAQHLLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDESNKELEAYQLDSQSDSTTEPEV
NLSETQTFKLNI
>Mature_251_residues
ALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNRDNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKV
KATANAEATNLVSKATYDAQHLLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWDE
LLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDESNKELEAYQLDSQSDSTTEPEVN
LSETQTFKLNI

Specific function: May act as a pilot protein, directing minCD to the polar septation sites or by inhibiting minCD at the midcell site of division. Required for polar localization of the chromosome during sporulation [H]

COG id: COG3599

COG function: function code D; Cell division initiation protein

Gene ontology:

Cell location: Cytoplasm. Note=Localized at the cell division site and found exclusively at the cell pole during sporulation [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gpsB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007793
- InterPro:   IPR019933 [H]

Pfam domain/function: PF05103 DivIVA [H]

EC number: NA

Molecular weight: Translated: 28934; Mature: 28803

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNRDNEARIKDLEEKLSYF
CCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQHLLDESKAKANQMLRDATD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWDELLQPTAIYLQNSDDAFKEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHEEEECCCHHHHHH
VKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDESNKELEAYQLDSQSDSTTEPEV
HHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCC
NLSETQTFKLNI
CCCCCCEEEECC
>Mature Secondary Structure 
ALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNRDNEARIKDLEEKLSYF
CEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQHLLDESKAKANQMLRDATD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWDELLQPTAIYLQNSDDAFKEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHEEEECCCHHHHHH
VKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDESNKELEAYQLDSQSDSTTEPEV
HHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCC
NLSETQTFKLNI
CCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9045828; 9219999; 9384377 [H]