| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
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The map label for this gene is licR [H]
Identifier: 19746303
GI number: 19746303
Start: 1113134
End: 1115128
Strand: Reverse
Name: licR [H]
Synonym: spyM18_1335
Alternate gene names: 19746303
Gene position: 1115128-1113134 (Counterclockwise)
Preceding gene: 19746304
Following gene: 19746302
Centisome position: 58.85
GC content: 38.4
Gene sequence:
>1995_bases ATGTTATCAAAAAAAGAACTGGCCATCATAACATTTCTAATCCGTCACAAAGAGCAGTTTGTCTCTAGTGCAACTCTGGC TGAGGTTATTGGTATGAGTGACCGTACGGTTAGGAAATACCTCAAAGAACTGATCAGTAGCCTTCCTGAACACGGAGCTC ACATCATTTCTAAACAAGGTCGAGGTTACTGCTTAGAAATTGACCATTCTATGGCATTTGACATCTTTTGGCAAGAAAGT GTGACGTCTAAAAAACGTTTGGCAGATGTGACTCAAGTGGAAGAATCGGTTGATCGAGAAGATTATGTGCTTCATAAATT CTTTTTTGAAGATGCCGTTCAGGATTTTGAAGAGCTTTGTCAAGAATTGTATATCAGTCGGACAACTTTAAAACATGTTT TAGCAGGCATTAAGGAGCGCATAATACCTTACCAGTTAGAGCTTGAAATAACTCACCCACATATTCAAATAAGAGGTAAA GAAGAGGACATTAGGCATTTTATCATGGATTATTTTTTTGTTACTAGTTTTGATAATACCTTGTCCACCATGGTAGGTAA TACCTTTCTTGAAGGTATTAATTTTGCAGAAATCATGATTATTGTCTTGGATGAATGTCGGGATGCTAAGTTGGAACTTT CTGATTTTGTCATGAATAATCTAGTCTTGCATATTGCCCTAATGGTTCAGCGTATTCGATCGGGGTGTCCATTAGAACTG TTTTCCATTCCAATAGCTATTCGTCAGTCTGATGAGTATCAAGTAGCTCTGCGCATTTTGTATCGAGTGGAAGAAGTGAT GGGGATACGTTTTCCTAAAGAGGAGGCTAATTATATTGCACTGCATCTAAAGGTCAAACATTCTGTTGGTAAGCATTGGC AAGATGATAATACCGATGAAAAGTTGCAGGACCATTTAAAAGCATGTATTGCCAAGATTAGTCAATTGACAGGCATGACT TTAGAAACAGATACTAATTTATTTCAAGGTTTATTAGCCCACATGATGCCCTTGACCACACGTCTTGAAAACCATATTCA GCTGACTAATCCTTTAACTGAGGAAATTAAAAGCCAGTATCCTGAAATATTTACCCTTACCAAGCAGATCTTTTCGGATT TGCTTGTATGTCAAAATAATGATGTCTCAGATGATGAATGGGCTTATATTAGTTTGCATTTAATGGCGGCCATTGAGCGT TATTCAAACCGTCATAAATTGAGGGTTCTAGTAGTTTGTGCCACAGGTTATGGTAGTGCCATGATGTTGAAAAATCGCTT GGAAAAGGAATTTGAAGGACGTTTGCGTATTGTCGATGTTATCAGTTACTATGAAATAACCGAAGAGCGACTGAAAACCG TTGATTTGATTATTTCCTCTATCAGCCTTGCCAATCTGATGTTTTTAATACCAGTGATTACTGTCAGTGTTTTTTTGTCA AATCAGGATATTGAAACTATTCGACAATTTATTGGAGAACAAGAAGGTATCAAGAAAGAGGTCAGTTTACCGTCACAGAT GAGTTTAGCAAAAGCAGAGCAGCTTCTAACAGGTGTTTTTAGCCCTAATCGTTTTCTTTATTTAGACGAGAAAATCTCAA AGGAAGACTTGCTTTTACGGATGATTGCTTGTCTTGACGAGGCGGGAACAGAAACGTTTGTAGAGGACTTCTATCATCAA ATGGTACTGAGGGAAAATTACAGCCCAGTCATCTATGGAGAAGTGCTTGCCTTTCCGCATCCTGCTAATCCCATGACTTA TTCTGAACAGGTAGTAGTGGCTATTTGCCGAGAGCCTCTTGAGTGGGACAAGGCGCATCAAGCTGTTCATTTTGTCTTTC TATTATCCCCGTCTAAAGGGCATAATCATAGGTTAAAATATGTATCACCAGGTTTGGCATCTTTTGTCAATCAGGTGGAG CTTCAGCAAGCGTTACTAGAAGAACCAAATTATCCCAAATTCATGACAGTGTTTACCCCACTTATTCATGATTAA
Upstream 100 bases:
>100_bases TTTCACAATCAATGCGGAAAATGATGGTCACCTTTTTCAGGAAATATTTGGTACACTAAAAGAGGGTAGAAAGCGTTTTC TAAAGTAGTAAGGAGGACTA
Downstream 100 bases:
>100_bases AACGATTAAAAGGAGAAACCTTATGAAATCTATTATGTTAGTTTGTAATGCCGGTATGTCAACTAGTATGTTGGTGACTA AGATGCAAAAAGCAGCCCAA
Product: transcriptional antiterminator
Products: NA
Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 664; Mature: 664
Protein sequence:
>664_residues MLSKKELAIITFLIRHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQES VTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHPHIQIRGK EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLELSDFVMNNLVLHIALMVQRIRSGCPLEL FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMT LETDTNLFQGLLAHMMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQIFSDLLVCQNNDVSDDEWAYISLHLMAAIER YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLIPVITVSVFLS NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQ MVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVE LQQALLEEPNYPKFMTVFTPLIHD
Sequences:
>Translated_664_residues MLSKKELAIITFLIRHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQES VTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHPHIQIRGK EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLELSDFVMNNLVLHIALMVQRIRSGCPLEL FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMT LETDTNLFQGLLAHMMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQIFSDLLVCQNNDVSDDEWAYISLHLMAAIER YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLIPVITVSVFLS NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQ MVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVE LQQALLEEPNYPKFMTVFTPLIHD >Mature_664_residues MLSKKELAIITFLIRHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQES VTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHPHIQIRGK EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLELSDFVMNNLVLHIALMVQRIRSGCPLEL FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMT LETDTNLFQGLLAHMMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQIFSDLLVCQNNDVSDDEWAYISLHLMAAIER YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLIPVITVSVFLS NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQ MVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVE LQQALLEEPNYPKFMTVFTPLIHD
Specific function: Positive regulator of the licABCH operon [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 76654; Mature: 76654
Theoretical pI: Translated: 5.33; Mature: 5.33
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSKKELAIITFLIRHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCC RGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELC CCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH QELYISRTTLKHVLAGIKERIIPYQLELEITHPHIQIRGKEEDIRHFIMDYFFVTSFDNT HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHCCHHH LSTMVGNTFLEGINFAEIMIIVLDECRDAKLELSDFVMNNLVLHIALMVQRIRSGCPLEL HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDE EECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCHH KLQDHLKACIAKISQLTGMTLETDTNLFQGLLAHMMPLTTRLENHIQLTNPLTEEIKSQY HHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHC PEIFTLTKQIFSDLLVCQNNDVSDDEWAYISLHLMAAIERYSNRHKLRVLVVCATGYGSA CHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH MMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLIPVITVSVFLS HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLR CCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH MIACLDEAGTETFVEDFYHQMVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVAICREPL HHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHEECCCCCCCCCCHHHHHHHHHHCCC EWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVELQQALLEEPNYPKFMTVFTP CHHHHHCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH LIHD HHCC >Mature Secondary Structure MLSKKELAIITFLIRHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCC RGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELC CCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH QELYISRTTLKHVLAGIKERIIPYQLELEITHPHIQIRGKEEDIRHFIMDYFFVTSFDNT HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHCCHHH LSTMVGNTFLEGINFAEIMIIVLDECRDAKLELSDFVMNNLVLHIALMVQRIRSGCPLEL HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDE EECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCHH KLQDHLKACIAKISQLTGMTLETDTNLFQGLLAHMMPLTTRLENHIQLTNPLTEEIKSQY HHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHC PEIFTLTKQIFSDLLVCQNNDVSDDEWAYISLHLMAAIERYSNRHKLRVLVVCATGYGSA CHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH MMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLIPVITVSVFLS HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLR CCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH MIACLDEAGTETFVEDFYHQMVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVAICREPL HHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHEECCCCCCCCCCHHHHHHHHHHCCC EWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVELQQALLEEPNYPKFMTVFTP CHHHHHCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH LIHD HHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8990303; 8969509; 9384377; 10438772 [H]