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The map label for this gene is apgM

Identifier: 18978331

GI number: 18978331

Start: 1808901

End: 1810136

Strand: Direct

Name: apgM

Synonym: PF1959

Alternate gene names: 18978331

Gene position: 1808901-1810136 (Clockwise)

Preceding gene: 18978330

Following gene: 18978332

Centisome position: 94.79

GC content: 45.47

Gene sequence:

>1236_bases
ATGAAGCAGAGAAAAGGAGTGCTTATTATTTTGGATGGCCTTGGAGATAGACCCATAAAAGAGCTCGGAGGCAAAACTCC
TTTAGAGTATGCAAATACACCCACCATGGATTACCTTGCCAAAATAGGGATTCTTGGGCAACAAGATCCAATAAAACCTG
GCCAACCAGCAGGAAGTGATACTGCCCACCTAAGCATCTTCGGATATGATCCCTATAAGAGTTACAGGGGGAGAGGATAT
TTTGAGGCTCTTGGTGTTGGTTTGGAGTTAGACGAGGACGATCTAGCATTCAGAGTAAATTTTGCAACTTTGGAGAATGG
AGTGATAACAGATAGAAGAGCCGGAAGGATTAGCACTGAGGAGGCTCATGAACTAGCAAAGGCAATACAGGAGAATGTAG
ATATTCCAGTAGACTTCATATTCAAAGGCGCAACTGGACACAGAGCTGTTCTGGTTTTGAAAGGAATGGCAGAGGGATAC
AAAGTTGGAGAGAACGATCCTCATGAGGCAGGAAAACCACCCCACCCCTTCACCTGGGAAGATGAAGCGAGCAAGAAGGT
TGCCGAAATCCTGGAAGAGTTTGTCAAAAAAGCCCATGAAGTCCTTGATAAGCATCCAATAAATGAGAAGCGCAGAAAAG
AAGGGAAACCAGTGGCAAATTACCTCTTAATTAGAGGGGCGGGTACTTATCCAAACATCCCAATGAAATTCACGGAGCAG
TGGAAGGTTAAGGCCGCCGCAGTAGTTGCAGTAGCTTTGGTAAAGGGAGTTGCAAAGGCCATTGGATTTGACGTTTATAC
TCCAAAAGGAGCTACTGGAGAGTACAATACCGATGAGATGGCCAAGGCTAGAAAGGCAGTTGAATTGCTGAAGGATTACG
ACTTTGTCTTCATACACTTCAAGCCAACAGATGCAGCTGGCCACGACAACAATCCAAAGCTAAAGGCAGAGCTAATAGAA
AGAGCCGATAGGATGATTAAATACATAGTGGATCACGTTGATCTGGAGGATGTAGTCATAGCAATAACTGGAGACCACTC
AACTCCATGTGAAGTTATGAACCACAGTGGGGATCCAGTTCCACTTTTGATAGCTGGAGGAGGAGTTAGGGCAGATTACA
CGGAGAAGTTCGGCGAAAGAGAGGCAATGCGCGGAGGCCTTGGAAGGATAAGAGGGCACGACATAGTCCCAATTATGATG
GATTTAATGAATAGGACTGAGAAGTTCGGCGCCTGA

Upstream 100 bases:

>100_bases
GATCTCGATTTTAAGACCTGGAGAGATTGTCAAGAAGAAAGTTGAAGATTGAACTTAAAGCTTATATTTTCCTTCTTCCA
CTCACTGTAGGTGATTAAAA

Downstream 100 bases:

>100_bases
TCTTTCTTATTTCTCTTTCTACTGAAATTACCTTTTCGTTTCTTAACTTAGCGTTTTGGTAGAAACCTTAATTAAGGTGT
ATATCAAAACTATTTTGGTG

Product: cofactor-independent phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; aPGAM

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MKQRKGVLIILDGLGDRPIKELGGKTPLEYANTPTMDYLAKIGILGQQDPIKPGQPAGSDTAHLSIFGYDPYKSYRGRGY
FEALGVGLELDEDDLAFRVNFATLENGVITDRRAGRISTEEAHELAKAIQENVDIPVDFIFKGATGHRAVLVLKGMAEGY
KVGENDPHEAGKPPHPFTWEDEASKKVAEILEEFVKKAHEVLDKHPINEKRRKEGKPVANYLLIRGAGTYPNIPMKFTEQ
WKVKAAAVVAVALVKGVAKAIGFDVYTPKGATGEYNTDEMAKARKAVELLKDYDFVFIHFKPTDAAGHDNNPKLKAELIE
RADRMIKYIVDHVDLEDVVIAITGDHSTPCEVMNHSGDPVPLLIAGGGVRADYTEKFGEREAMRGGLGRIRGHDIVPIMM
DLMNRTEKFGA

Sequences:

>Translated_411_residues
MKQRKGVLIILDGLGDRPIKELGGKTPLEYANTPTMDYLAKIGILGQQDPIKPGQPAGSDTAHLSIFGYDPYKSYRGRGY
FEALGVGLELDEDDLAFRVNFATLENGVITDRRAGRISTEEAHELAKAIQENVDIPVDFIFKGATGHRAVLVLKGMAEGY
KVGENDPHEAGKPPHPFTWEDEASKKVAEILEEFVKKAHEVLDKHPINEKRRKEGKPVANYLLIRGAGTYPNIPMKFTEQ
WKVKAAAVVAVALVKGVAKAIGFDVYTPKGATGEYNTDEMAKARKAVELLKDYDFVFIHFKPTDAAGHDNNPKLKAELIE
RADRMIKYIVDHVDLEDVVIAITGDHSTPCEVMNHSGDPVPLLIAGGGVRADYTEKFGEREAMRGGLGRIRGHDIVPIMM
DLMNRTEKFGA
>Mature_411_residues
MKQRKGVLIILDGLGDRPIKELGGKTPLEYANTPTMDYLAKIGILGQQDPIKPGQPAGSDTAHLSIFGYDPYKSYRGRGY
FEALGVGLELDEDDLAFRVNFATLENGVITDRRAGRISTEEAHELAKAIQENVDIPVDFIFKGATGHRAVLVLKGMAEGY
KVGENDPHEAGKPPHPFTWEDEASKKVAEILEEFVKKAHEVLDKHPINEKRRKEGKPVANYLLIRGAGTYPNIPMKFTEQ
WKVKAAAVVAVALVKGVAKAIGFDVYTPKGATGEYNTDEMAKARKAVELLKDYDFVFIHFKPTDAAGHDNNPKLKAELIE
RADRMIKYIVDHVDLEDVVIAITGDHSTPCEVMNHSGDPVPLLIAGGGVRADYTEKFGEREAMRGGLGRIRGHDIVPIMM
DLMNRTEKFGA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG3635

COG function: function code G; Predicted phosphoglycerate mutase, AP superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APGM_PYRFU (P58814)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579688.1
- ProteinModelPortal:   P58814
- SMR:   P58814
- EnsemblBacteria:   EBPYRT00000004646
- GeneID:   1469841
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1959
- NMPDR:   fig|186497.1.peg.2011
- GeneTree:   EBGT00050000023120
- HOGENOM:   HBG463247
- OMA:   DIAFRCN
- ProtClustDB:   PRK04024
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01402_A
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR004456
- InterPro:   IPR006124
- Gene3D:   G3DSA:3.40.720.10
- PIRSF:   PIRSF006392
- TIGRFAMs:   TIGR00306

Pfam domain/function: PF01676 Metalloenzyme; PF10143 PhosphMutase; SSF53649 Alkaline_phosphatase_core

EC number: =5.4.2.1

Molecular weight: Translated: 45314; Mature: 45314

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRKGVLIILDGLGDRPIKELGGKTPLEYANTPTMDYLAKIGILGQQDPIKPGQPAGSD
CCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
TAHLSIFGYDPYKSYRGRGYFEALGVGLELDEDDLAFRVNFATLENGVITDRRAGRISTE
CEEEEEEECCHHHHHCCCCCHHHHCCCCEECCCCEEEEEEEEEECCCCCCCCCCCCCCHH
EAHELAKAIQENVDIPVDFIFKGATGHRAVLVLKGMAEGYKVGENDPHEAGKPPHPFTWE
HHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
DEASKKVAEILEEFVKKAHEVLDKHPINEKRRKEGKPVANYLLIRGAGTYPNIPMKFTEQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHEEEEEECCCCCCCCCCCCHH
WKVKAAAVVAVALVKGVAKAIGFDVYTPKGATGEYNTDEMAKARKAVELLKDYDFVFIHF
HHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
KPTDAAGHDNNPKLKAELIERADRMIKYIVDHVDLEDVVIAITGDHSTPCEVMNHSGDPV
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCCE
PLLIAGGGVRADYTEKFGEREAMRGGLGRIRGHDIVPIMMDLMNRTEKFGA
EEEEECCCCCCCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQRKGVLIILDGLGDRPIKELGGKTPLEYANTPTMDYLAKIGILGQQDPIKPGQPAGSD
CCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
TAHLSIFGYDPYKSYRGRGYFEALGVGLELDEDDLAFRVNFATLENGVITDRRAGRISTE
CEEEEEEECCHHHHHCCCCCHHHHCCCCEECCCCEEEEEEEEEECCCCCCCCCCCCCCHH
EAHELAKAIQENVDIPVDFIFKGATGHRAVLVLKGMAEGYKVGENDPHEAGKPPHPFTWE
HHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
DEASKKVAEILEEFVKKAHEVLDKHPINEKRRKEGKPVANYLLIRGAGTYPNIPMKFTEQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHEEEEEECCCCCCCCCCCCHH
WKVKAAAVVAVALVKGVAKAIGFDVYTPKGATGEYNTDEMAKARKAVELLKDYDFVFIHF
HHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
KPTDAAGHDNNPKLKAELIERADRMIKYIVDHVDLEDVVIAITGDHSTPCEVMNHSGDPV
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCCE
PLLIAGGGVRADYTEKFGEREAMRGGLGRIRGHDIVPIMMDLMNRTEKFGA
EEEEECCCCCCCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12076796