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The map label for this gene is yleA [C]

Identifier: 18978284

GI number: 18978284

Start: 1762991

End: 1764268

Strand: Direct

Name: yleA [C]

Synonym: PF1912

Alternate gene names: 18978284

Gene position: 1762991-1764268 (Clockwise)

Preceding gene: 18978280

Following gene: 18978285

Centisome position: 92.39

GC content: 40.45

Gene sequence:

>1278_bases
ATGACAAAAGTATACATTGAGAACTATGGATGTGCGAGAAATAGAGCAGATGGAGAGATTATGGCAGGCCTACTTTTGTC
TTCAGGTTATGAGATAGTAGAAGGAGAAGAAAATGCTGACATTGTTGTTGTTAATTCATGTGCCGTAAAAGATCCCACAG
AAGTAAAGATTGCGAGGAGAATAAGAGAGTTATTAGATAGGGGAAAGAAAGTTATAGTTACAGGATGCCTTCCTCACGTT
AATCCCGATGCTATTGATGAGAGAGTGTCAGCAGTTTTGGGAGTTAAAAGCATAGACAGAATAGTTCAAGCAGTGGAATA
TGCCTTAAGAGGTGAGAAGCTCATAAGTGTCCCTGACTGGAGAAAGAGAAATCTTGATAAGCTAGATTTTCCCAGGTTAA
GCCCGAGAGGAGTTCACTTTATTCTCCCAATTGCTGAAGGGTGTTTAAATGGTTGTACCTACTGTGCCACTAGATCAGCT
AGAGGAGTCCTCAAAAGCTACTCTCCAGAGAAGATTGTTGAATGGGTAAAGTGGGCCATTAGACAAGGGTACAAAGAAAT
TTGGCTTTCAGCGGAGGATACGGGATGCTACGGATTCGACATAGGAACTAACCTAGCAAAGTTATTAGATGAAATTACAG
CAATAGAAGGCGAATTTAGGATTAGGGTTGGAATGATGAATCCAAATCATGTATTGAAGTTCCTAGACGAGCTTATAGAA
GCATACAAGGATGAAAAAGTTTACAAGTTCCTTCATTTGCCAGTTCAGAGTGGAGATAACGAAATTTTGAGAAGAATGGG
GAGAACATACACAGTGGAAGAATTTGAGGAAATAGTTAACGCTTTCAGAAGAGAGTTTCCAGATCTAAATTTACATACGG
ACATAATAGTTGGTTTCCCAGGAGAAAGTGAAGAAGCATTTCAAAGAAGTTTAGAGCTAATCAAGAGGATAAAGCCCGAT
AAAGTAAATGTATCTCGCTATTCCCCAAGACCTGGGACAATTGCAGCTAAGTGGAAGCAACTCCCAGGATGGGTCGTCAA
GGAGAGGTCAAGAATTATGCACAGGGTGAGACTTCAGATAAGCTATGAAATCAACCAGAGATACGTAGGTAGGAAAGTCG
ACATTCTCGTTCATGGAGAAGGAAAGAAAGGAAATGTTGATGCCGTAACGATGAATTACAAGCACATAATAATCCCAAGA
GGAGAAAAAGGAGAATTCGCTAGGGCAAAGGTAAATGGAGCCACTTCCACTTATCTTCTTGGCGAGATAGTAGACTAA

Upstream 100 bases:

>100_bases
TCAAATGTTGTGAACATTGAGTGTTTATAAAGATATTGTAAACCAAAGGTTATAGAGCATAAGAGAAAATTACTTAAAAT
CCCTTGAATATGAAGGTGCG

Downstream 100 bases:

>100_bases
ACTTTTTAATCTTCAAATTCCAAATTTATTCTAGGGGATGACAATGAAAGGGCGGTTGCAAGCTCATAACATTAGGATTA
GAACATTCATCCACGCAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTKVYIENYGCARNRADGEIMAGLLLSSGYEIVEGEENADIVVVNSCAVKDPTEVKIARRIRELLDRGKKVIVTGCLPHV
NPDAIDERVSAVLGVKSIDRIVQAVEYALRGEKLISVPDWRKRNLDKLDFPRLSPRGVHFILPIAEGCLNGCTYCATRSA
RGVLKSYSPEKIVEWVKWAIRQGYKEIWLSAEDTGCYGFDIGTNLAKLLDEITAIEGEFRIRVGMMNPNHVLKFLDELIE
AYKDEKVYKFLHLPVQSGDNEILRRMGRTYTVEEFEEIVNAFRREFPDLNLHTDIIVGFPGESEEAFQRSLELIKRIKPD
KVNVSRYSPRPGTIAAKWKQLPGWVVKERSRIMHRVRLQISYEINQRYVGRKVDILVHGEGKKGNVDAVTMNYKHIIIPR
GEKGEFARAKVNGATSTYLLGEIVD

Sequences:

>Translated_425_residues
MTKVYIENYGCARNRADGEIMAGLLLSSGYEIVEGEENADIVVVNSCAVKDPTEVKIARRIRELLDRGKKVIVTGCLPHV
NPDAIDERVSAVLGVKSIDRIVQAVEYALRGEKLISVPDWRKRNLDKLDFPRLSPRGVHFILPIAEGCLNGCTYCATRSA
RGVLKSYSPEKIVEWVKWAIRQGYKEIWLSAEDTGCYGFDIGTNLAKLLDEITAIEGEFRIRVGMMNPNHVLKFLDELIE
AYKDEKVYKFLHLPVQSGDNEILRRMGRTYTVEEFEEIVNAFRREFPDLNLHTDIIVGFPGESEEAFQRSLELIKRIKPD
KVNVSRYSPRPGTIAAKWKQLPGWVVKERSRIMHRVRLQISYEINQRYVGRKVDILVHGEGKKGNVDAVTMNYKHIIIPR
GEKGEFARAKVNGATSTYLLGEIVD
>Mature_424_residues
TKVYIENYGCARNRADGEIMAGLLLSSGYEIVEGEENADIVVVNSCAVKDPTEVKIARRIRELLDRGKKVIVTGCLPHVN
PDAIDERVSAVLGVKSIDRIVQAVEYALRGEKLISVPDWRKRNLDKLDFPRLSPRGVHFILPIAEGCLNGCTYCATRSAR
GVLKSYSPEKIVEWVKWAIRQGYKEIWLSAEDTGCYGFDIGTNLAKLLDEITAIEGEFRIRVGMMNPNHVLKFLDELIEA
YKDEKVYKFLHLPVQSGDNEILRRMGRTYTVEEFEEIVNAFRREFPDLNLHTDIIVGFPGESEEAFQRSLELIKRIKPDK
VNVSRYSPRPGTIAAKWKQLPGWVVKERSRIMHRVRLQISYEINQRYVGRKVDILVHGEGKKGNVDAVTMNYKHIIIPRG
EKGEFARAKVNGATSTYLLGEIVD

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=407, Percent_Identity=36.6093366093366, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI28872782, Length=481, Percent_Identity=24.3243243243243, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI28872784, Length=478, Percent_Identity=25.1046025104602, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1786882, Length=401, Percent_Identity=31.4214463840399, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787057, Length=446, Percent_Identity=29.5964125560538, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71996771, Length=357, Percent_Identity=33.3333333333333, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17553146, Length=470, Percent_Identity=28.0851063829787, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19922432, Length=433, Percent_Identity=36.2586605080831, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI21356207, Length=440, Percent_Identity=28.1818181818182, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48291; Mature: 48160

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVYIENYGCARNRADGEIMAGLLLSSGYEIVEGEENADIVVVNSCAVKDPTEVKIARR
CCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHH
IRELLDRGKKVIVTGCLPHVNPDAIDERVSAVLGVKSIDRIVQAVEYALRGEKLISVPDW
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCH
RKRNLDKLDFPRLSPRGVHFILPIAEGCLNGCTYCATRSARGVLKSYSPEKIVEWVKWAI
HHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RQGYKEIWLSAEDTGCYGFDIGTNLAKLLDEITAIEGEFRIRVGMMNPNHVLKFLDELIE
HCCHHHHEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
AYKDEKVYKFLHLPVQSGDNEILRRMGRTYTVEEFEEIVNAFRREFPDLNLHTDIIVGFP
HHCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GESEEAFQRSLELIKRIKPDKVNVSRYSPRPGTIAAKWKQLPGWVVKERSRIMHRVRLQI
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHEEE
SYEINQRYVGRKVDILVHGEGKKGNVDAVTMNYKHIIIPRGEKGEFARAKVNGATSTYLL
EEEECCHHCCCEEEEEEECCCCCCCEEEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEE
GEIVD
EEECC
>Mature Secondary Structure 
TKVYIENYGCARNRADGEIMAGLLLSSGYEIVEGEENADIVVVNSCAVKDPTEVKIARR
CEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHH
IRELLDRGKKVIVTGCLPHVNPDAIDERVSAVLGVKSIDRIVQAVEYALRGEKLISVPDW
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCH
RKRNLDKLDFPRLSPRGVHFILPIAEGCLNGCTYCATRSARGVLKSYSPEKIVEWVKWAI
HHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RQGYKEIWLSAEDTGCYGFDIGTNLAKLLDEITAIEGEFRIRVGMMNPNHVLKFLDELIE
HCCHHHHEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
AYKDEKVYKFLHLPVQSGDNEILRRMGRTYTVEEFEEIVNAFRREFPDLNLHTDIIVGFP
HHCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GESEEAFQRSLELIKRIKPDKVNVSRYSPRPGTIAAKWKQLPGWVVKERSRIMHRVRLQI
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHEEE
SYEINQRYVGRKVDILVHGEGKKGNVDAVTMNYKHIIIPRGEKGEFARAKVNGATSTYLL
EEEECCHHCCCEEEEEEECCCCCCCEEEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEE
GEIVD
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]