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The map label for this gene is pyrK [H]

Identifier: 18978283

GI number: 18978283

Start: 1761982

End: 1762851

Strand: Reverse

Name: pyrK [H]

Synonym: PF1911

Alternate gene names: 18978283

Gene position: 1762851-1761982 (Counterclockwise)

Preceding gene: 18978288

Following gene: 18978282

Centisome position: 92.38

GC content: 42.76

Gene sequence:

>870_bases
ATGTATAAAATCCTCGAGAAAAAGGAAATCGCAATGAGAAATACCTGGTATAAAGTTTACGCACCTCACGTAGCTAAAAA
AGTTCAGCCAGGACAGTTCGTCATAGTTAGAGCCTTTCCGAACGGAGAAAGAATTCCTTTGACTCCTGTAATGTGGGATA
GAGAAGAGGGGTGGATAGTTCTAATAGTATTTACAAGAGGAAAGACAACAATGAGGATGGCAGTGGAGCTTAAGGAAGGG
GATTCACTGTTAAACGTAGCGGGACCACTAGGGACGCCAGTTCCTATGGAAAAGTTTGGAAAAATACTTGCAATAGGTGC
TTATACTGGAATAGTGGAAGTGTATCCAATTGCAAAAGCCTGGCAGGAAATAGGAAATGACGTAACAACACTTCACGTAA
CTTTCGAGCCAATGGTAATTCTCAAGGAAGAACTTGAGAAGGCAGTAACCAGGCACATTGTAGAACCTGTCCCATTGAAT
CCAAATCAGGACTTCTTAGCTAACATGAAAAACGTGTCTCAAAGACTCAAAGAAAAGGTTAGAGAGCTTTTAGAAAGTGA
AGACTGGGATTTAGTATTTATGGTCGGCCCAGTTGGAGACCAAAAGCAGGTATTTGAAGTTGTAAAAGAGTATGGTGTCC
CAATGAAGGTTGACCTCCATCCCATCATGGTTGATGGGACTGGGATGTGTGGGGCTTGTAGGGTTACAGTTGGTGGTGAA
GTCAAATTCGCATGCGTAGACGGCCCAGAATTCGACGCATATCAAGTAGATTGGGATGAGCTGATTCACAGAGTGGGGTT
CTATGCCAAGTTGGAAAAATTAGCTCTGGAGAAATATATGGAAGAGCTTAAGGCTAAGGGGGTGATTTGA

Upstream 100 bases:

>100_bases
TATGCTCTATAACCTTTGGTTTACAATATCTTTATAAACACTCAATGTTCACAACATTTGAGTATGTTCAAAAATGTTCA
CGTGATCGGAGGTGTTCATC

Downstream 100 bases:

>100_bases
ATGCCTAGGCTTATTAAAGAGAGGGTTCCTACTCCTGAGAGGTCTGTTGGGGAGAGGGTTAGGGATTTTGGTGAGGTTAA
TCTTGGTTATTCTTGGGAGT

Product: ferredoxin-NADP(+) reductase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIVLIVFTRGKTTMRMAVELKEG
DSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKAWQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLN
PNQDFLANMKNVSQRLKEKVRELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGE
VKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEELKAKGVI

Sequences:

>Translated_289_residues
MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIVLIVFTRGKTTMRMAVELKEG
DSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKAWQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLN
PNQDFLANMKNVSQRLKEKVRELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGE
VKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEELKAKGVI
>Mature_289_residues
MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIVLIVFTRGKTTMRMAVELKEG
DSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKAWQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLN
PNQDFLANMKNVSQRLKEKVRELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGE
VKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEELKAKGVI

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 32738; Mature: 32738

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIV
CCCCCCHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEE
LIVFTRGKTTMRMAVELKEGDSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKA
EEEEECCCEEEEEEEEECCCCCEEEECCCCCCCCCHHHCCCEEEEEEHHCEEEEHHHHHH
WQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLNPNQDFLANMKNVSQRLKEKV
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGE
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECEEEEEECCCCCCEEEEEECCE
VKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEELKAKGVI
EEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIV
CCCCCCHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEE
LIVFTRGKTTMRMAVELKEGDSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKA
EEEEECCCEEEEEEEEECCCCCEEEECCCCCCCCCHHHCCCEEEEEEHHCEEEEHHHHHH
WQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLNPNQDFLANMKNVSQRLKEKV
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGE
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECEEEEEECCCCCCEEEEEECCE
VKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEELKAKGVI
EEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]