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The map label for this gene is mat [H]

Identifier: 18978238

GI number: 18978238

Start: 1721830

End: 1723035

Strand: Reverse

Name: mat [H]

Synonym: PF1866

Alternate gene names: 18978238

Gene position: 1723035-1721830 (Counterclockwise)

Preceding gene: 18978243

Following gene: 18978236

Centisome position: 90.29

GC content: 43.37

Gene sequence:

>1206_bases
ATGGCGAGGAACATAGTTGTTGAGGAGATAGTTAGAACTCCAGTGGAGATGCAGCAGGTTGAACTTGTAGAGAGAAAGGG
GATTGGTCATCCAGACAGCATAGCTGATGGAATCGCTGAAGCGGTTAGCAGAGCTCTATGTAGGGAGTATATTAGGAGGT
ATGGAGTAATTCTTCATCACAACACCGATCAAGTTGAGGTTGTCGGCGGTAGGGCGTATCCCAGGTTTGGTGGTGGAGAG
GTTGTAAAGCCAATCTACATTTTACTTTCAGGTAGAGCAGTTGAGCTAGTTGATCAAGAACTCTTTCCAGTTCATGAAGT
TGCCATTAAGGCTGCAAAGAACTATCTCAAGAATGCAATTAGACACTTAGACGTTGAAAACCATGTTATCATTGATTCAA
GAATTGGGCAGGGTAGCGTTGATCTTGTAAGTGTATTTAACAAGGCAAGGGAAAACCCAATTCCATTGGCAAATGATACT
TCATTTGGAGTTGGATACGCCCCATTGAGCGAGACAGAGAGATTAGTTCTTGAAACTGAGAAGTTGCTTAACAGCGAGAA
GTTCAAGAAAGAATACCCAGCCGTTGGAGAGGACATTAAGGTAATGGGTCTAAGAAGAGGAAACGAGATCGATTTGACTA
TAGCAGCTGCCATTGTTGATAGTGAAGTGGCAACTCCCAAAGAATACCTGGAAGTAAAGGACAAGATAAAAGAGGCCGTA
GAAGAATTAGCTAAAGAGATAACCTCGAGAAAAGTTAACATATACGTCAACACAGCTGACGATCCCGAGAGAGGGATATA
CTACATAACAGTTACTGGAACTAGTGCCGAGGCAGGAGATGACGGTTCGGTTGGAAGAGGAAACAGAGTTAATGGTCTTA
TAACCCCAAATAGGCACATGAGCATGGAAGCTGCTGCGGGTAAGAACCCCGTCAGCCACGTTGGAAAGATCTACAACATT
CTCGCAATGCTAATTGCAGAGGACATAGCTAAGACACTTCCAGTGGAGGAAGTTTATGTGAGAATATTAAGTCAGATCGG
AAAGCCAATTGACCAGCCATTAGTAGCTAGCATACAGGTAATTCCAAAGCCTGGACATAGCGTGAAGGAATTCGAAAAGG
ATGCGTATTCAATAGCTGACGAGTGGTTGGCAAATATAACAAAAGTTCAGAAGATGATTCTCGAGGACAAGATCTCTGTG
TTCTAG

Upstream 100 bases:

>100_bases
CATTGTGGGTCTAAATAACTGGGAGTAATAAGGATTGAATATTTTATATGCCGAAAATTATATAAACATTTGACAAAGTT
GGATAAGCGAGGTGACGCTC

Downstream 100 bases:

>100_bases
CTAATTTCCTTAAATTCCTTTTTTAGCAGAGCAAGTTCATTAGGTTTGAAAGCTTTATCTTCTATGATCAAAACTAAGGA
AGAGTTATTGAGCATCAAGT

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MARNIVVEEIVRTPVEMQQVELVERKGIGHPDSIADGIAEAVSRALCREYIRRYGVILHHNTDQVEVVGGRAYPRFGGGE
VVKPIYILLSGRAVELVDQELFPVHEVAIKAAKNYLKNAIRHLDVENHVIIDSRIGQGSVDLVSVFNKARENPIPLANDT
SFGVGYAPLSETERLVLETEKLLNSEKFKKEYPAVGEDIKVMGLRRGNEIDLTIAAAIVDSEVATPKEYLEVKDKIKEAV
EELAKEITSRKVNIYVNTADDPERGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHMSMEAAAGKNPVSHVGKIYNI
LAMLIAEDIAKTLPVEEVYVRILSQIGKPIDQPLVASIQVIPKPGHSVKEFEKDAYSIADEWLANITKVQKMILEDKISV
F

Sequences:

>Translated_401_residues
MARNIVVEEIVRTPVEMQQVELVERKGIGHPDSIADGIAEAVSRALCREYIRRYGVILHHNTDQVEVVGGRAYPRFGGGE
VVKPIYILLSGRAVELVDQELFPVHEVAIKAAKNYLKNAIRHLDVENHVIIDSRIGQGSVDLVSVFNKARENPIPLANDT
SFGVGYAPLSETERLVLETEKLLNSEKFKKEYPAVGEDIKVMGLRRGNEIDLTIAAAIVDSEVATPKEYLEVKDKIKEAV
EELAKEITSRKVNIYVNTADDPERGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHMSMEAAAGKNPVSHVGKIYNI
LAMLIAEDIAKTLPVEEVYVRILSQIGKPIDQPLVASIQVIPKPGHSVKEFEKDAYSIADEWLANITKVQKMILEDKISV
F
>Mature_400_residues
ARNIVVEEIVRTPVEMQQVELVERKGIGHPDSIADGIAEAVSRALCREYIRRYGVILHHNTDQVEVVGGRAYPRFGGGEV
VKPIYILLSGRAVELVDQELFPVHEVAIKAAKNYLKNAIRHLDVENHVIIDSRIGQGSVDLVSVFNKARENPIPLANDTS
FGVGYAPLSETERLVLETEKLLNSEKFKKEYPAVGEDIKVMGLRRGNEIDLTIAAAIVDSEVATPKEYLEVKDKIKEAVE
ELAKEITSRKVNIYVNTADDPERGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHMSMEAAAGKNPVSHVGKIYNIL
AMLIAEDIAKTLPVEEVYVRILSQIGKPIDQPLVASIQVIPKPGHSVKEFEKDAYSIADEWLANITKVQKMILEDKISVF

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 44281; Mature: 44150

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNIVVEEIVRTPVEMQQVELVERKGIGHPDSIADGIAEAVSRALCREYIRRYGVILHH
CCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
NTDQVEVVGGRAYPRFGGGEVVKPIYILLSGRAVELVDQELFPVHEVAIKAAKNYLKNAI
CCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RHLDVENHVIIDSRIGQGSVDLVSVFNKARENPIPLANDTSFGVGYAPLSETERLVLETE
HHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KLLNSEKFKKEYPAVGEDIKVMGLRRGNEIDLTIAAAIVDSEVATPKEYLEVKDKIKEAV
HHHCHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHH
EELAKEITSRKVNIYVNTADDPERGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHM
HHHHHHHHCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCC
SMEAAAGKNPVSHVGKIYNILAMLIAEDIAKTLPVEEVYVRILSQIGKPIDQPLVASIQV
EEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHEEE
IPKPGHSVKEFEKDAYSIADEWLANITKVQKMILEDKISVF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARNIVVEEIVRTPVEMQQVELVERKGIGHPDSIADGIAEAVSRALCREYIRRYGVILHH
CCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
NTDQVEVVGGRAYPRFGGGEVVKPIYILLSGRAVELVDQELFPVHEVAIKAAKNYLKNAI
CCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RHLDVENHVIIDSRIGQGSVDLVSVFNKARENPIPLANDTSFGVGYAPLSETERLVLETE
HHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KLLNSEKFKKEYPAVGEDIKVMGLRRGNEIDLTIAAAIVDSEVATPKEYLEVKDKIKEAV
HHHCHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHH
EELAKEITSRKVNIYVNTADDPERGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHM
HHHHHHHHCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCC
SMEAAAGKNPVSHVGKIYNILAMLIAEDIAKTLPVEEVYVRILSQIGKPIDQPLVASIQV
EEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHEEE
IPKPGHSVKEFEKDAYSIADEWLANITKVQKMILEDKISVF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]