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The map label for this gene is 18978219

Identifier: 18978219

GI number: 18978219

Start: 1703344

End: 1704669

Strand: Reverse

Name: 18978219

Synonym: PF1847

Alternate gene names: NA

Gene position: 1704669-1703344 (Counterclockwise)

Preceding gene: 18978220

Following gene: 18978215

Centisome position: 89.33

GC content: 42.01

Gene sequence:

>1326_bases
ATGCCAGTAATAGAAGAGATTCCAACCGTGAAGTTTGAGAGAGTAGGAATGCACTCCCACATAAAGGGCCTTGGACTAGA
TGAGAATGGTAAGGCAAAGTTCATTGGAGATGGAATGGTTGGTCAAGTAAAGGCGAGAGAAGCGGCGGGAATAGCGGTAA
AATTGATTAAACAAGGTAAACTAGCTGGAAAGGGAATTCTCTTAGTAGGTCCAACAGGGAGTGGAAAAACCGCAATTGCA
ATGGGTATCGCGAGAGAGCTTGGTGAAGACGTTCCATTTGTTCAAATAAGCGGGAGTGAAATATATTCAGCAGAGATGAA
AAAGACAGAATTCCTCAAGCAAGCTTTGAGAAGGGCCATAGGTGTGAGAATAAGTGAGGAAAGGAAAGTATACGAAGGAA
AAGTAGAAAAGATTGAAATAAGAAGAACAAGGCATCCCTTCAATCCTTACATAGAAATTCCGGAAAGTGTAGTCCTAACT
CTAAAAACAAAGGACGACTCAAAGACCATAAGGGCAGGAAGAGAGATAGCATATCAAATACTTGAGATGGGTATTGAAGA
GGGAGATGTTATTCAAATTGATGCTGAAACTGGAAGAGTTTCAAGAATTGGGACTACTAAAGAGGAAGAAGGGCTCTTCT
TCCGAAAGAAAGTTGAGATGCCCACTGGTCCAGTATTGAAGATTAAGGAATTTACATATACTGTTACTCTTCACGATTTG
GATGTTGTTAATGCAAGAGCTGGTGGAATATTTAGCCTTCTCTTTGGAGGTAGAATGGAAATTAACGACGAGATAAGGGA
GAGAGTAGATCAAACAGTTAAACAGTGGGTTGAGGAAGGAAAGGCAACTTTGGTCCCAGGAGTGCTCTTCATTGATGAAT
GTCACATGTTAGATATTGAAGCATTCTCATTCTTGGCTAGAGCCATGGAAAGTGAGCTTGCTCCGATCCTAATCTTAGCT
ACGAACAGGGGTATGACAAAGATAAGAGGAACTGACATAGAGTCTCCACATGGAATTCCACTTGACATGCTTGACAGATT
ACTCATAATAAATACCGAACCATACAAGAAGGAAGAGATAAGGGAGATTGTAAAGATAAGAGCAAGAGAAGAGAAGATAG
AGCTTAGCGAAGAGGCTCTCGAATATCTAGCAGAGCTGGGTGAGCAGACGAGCCTTAGATATGCAGTGCAACTACTGGCT
CCAGCTAGCATAATTGCTGGAGGAAAGAGGGTTGAGAAAGAGCACGTTGAAAAGGCTAGGGAATACTTCGCAGACGTGAA
GAGAAGCATAGCCTTTGTAGAGAAGGTGGAAGGAATGCTCAAGTGA

Upstream 100 bases:

>100_bases
GGCTCATAAAATGCTTGGGAGATGATTTCTTCTACCGTCAATTTTTTAATTTGCATATTTTAATAACAAAATGGAACAAA
AATTCTGAGGAGGTGAGTAG

Downstream 100 bases:

>100_bases
TTGAGCAGAGAATGTCAAAGAAAAGTGAACCAATCCAGTGAACTAAAAAGCTTGGTACTATACTTTCCTCTTTTAAATCT
ATTTTTGCAAATATTATGCC

Product: tbp-interacting protein tip49

Products: NA

Alternate protein names: TIP49 Domain Protein; TIP49-Like Protein; TIP49 Domain-Containing Protein; Tbp-Interacting Protein Tip; DNA Helicase; TIP49-Like; TBP-Interacting Proten; TIP49 C-Terminal Domain Family Protein; DNA Helicase TIP

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPVIEEIPTVKFERVGMHSHIKGLGLDENGKAKFIGDGMVGQVKAREAAGIAVKLIKQGKLAGKGILLVGPTGSGKTAIA
MGIARELGEDVPFVQISGSEIYSAEMKKTEFLKQALRRAIGVRISEERKVYEGKVEKIEIRRTRHPFNPYIEIPESVVLT
LKTKDDSKTIRAGREIAYQILEMGIEEGDVIQIDAETGRVSRIGTTKEEEGLFFRKKVEMPTGPVLKIKEFTYTVTLHDL
DVVNARAGGIFSLLFGGRMEINDEIRERVDQTVKQWVEEGKATLVPGVLFIDECHMLDIEAFSFLARAMESELAPILILA
TNRGMTKIRGTDIESPHGIPLDMLDRLLIINTEPYKKEEIREIVKIRAREEKIELSEEALEYLAELGEQTSLRYAVQLLA
PASIIAGGKRVEKEHVEKAREYFADVKRSIAFVEKVEGMLK

Sequences:

>Translated_441_residues
MPVIEEIPTVKFERVGMHSHIKGLGLDENGKAKFIGDGMVGQVKAREAAGIAVKLIKQGKLAGKGILLVGPTGSGKTAIA
MGIARELGEDVPFVQISGSEIYSAEMKKTEFLKQALRRAIGVRISEERKVYEGKVEKIEIRRTRHPFNPYIEIPESVVLT
LKTKDDSKTIRAGREIAYQILEMGIEEGDVIQIDAETGRVSRIGTTKEEEGLFFRKKVEMPTGPVLKIKEFTYTVTLHDL
DVVNARAGGIFSLLFGGRMEINDEIRERVDQTVKQWVEEGKATLVPGVLFIDECHMLDIEAFSFLARAMESELAPILILA
TNRGMTKIRGTDIESPHGIPLDMLDRLLIINTEPYKKEEIREIVKIRAREEKIELSEEALEYLAELGEQTSLRYAVQLLA
PASIIAGGKRVEKEHVEKAREYFADVKRSIAFVEKVEGMLK
>Mature_440_residues
PVIEEIPTVKFERVGMHSHIKGLGLDENGKAKFIGDGMVGQVKAREAAGIAVKLIKQGKLAGKGILLVGPTGSGKTAIAM
GIARELGEDVPFVQISGSEIYSAEMKKTEFLKQALRRAIGVRISEERKVYEGKVEKIEIRRTRHPFNPYIEIPESVVLTL
KTKDDSKTIRAGREIAYQILEMGIEEGDVIQIDAETGRVSRIGTTKEEEGLFFRKKVEMPTGPVLKIKEFTYTVTLHDLD
VVNARAGGIFSLLFGGRMEINDEIRERVDQTVKQWVEEGKATLVPGVLFIDECHMLDIEAFSFLARAMESELAPILILAT
NRGMTKIRGTDIESPHGIPLDMLDRLLIINTEPYKKEEIREIVKIRAREEKIELSEEALEYLAELGEQTSLRYAVQLLAP
ASIIAGGKRVEKEHVEKAREYFADVKRSIAFVEKVEGMLK

Specific function: Unknown

COG id: COG1224

COG function: function code K; DNA helicase TIP49, TBP-interacting protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506753, Length=441, Percent_Identity=49.4331065759637, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI5730023, Length=446, Percent_Identity=45.2914798206278, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17542510, Length=428, Percent_Identity=47.196261682243, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17558290, Length=411, Percent_Identity=42.0924574209246, Blast_Score=312, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6325021, Length=437, Percent_Identity=43.9359267734554, Blast_Score=373, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6320396, Length=441, Percent_Identity=45.8049886621315, Blast_Score=369, Evalue=1e-103,
Organism=Drosophila melanogaster, GI17737635, Length=441, Percent_Identity=45.8049886621315, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI21358125, Length=441, Percent_Identity=47.1655328798186, Blast_Score=350, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49271; Mature: 49140

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVIEEIPTVKFERVGMHSHIKGLGLDENGKAKFIGDGMVGQVKAREAAGIAVKLIKQGK
CCCCHHCCCCCHHHCCCHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHCCHHHEEHHCCC
LAGKGILLVGPTGSGKTAIAMGIARELGEDVPFVQISGSEIYSAEMKKTEFLKQALRRAI
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
GVRISEERKVYEGKVEKIEIRRTRHPFNPYIEIPESVVLTLKTKDDSKTIRAGREIAYQI
CCEECCCCHHHCCCCEEEEEECCCCCCCCCEECCCEEEEEEEECCCCHHHHHHHHHHHHH
LEMGIEEGDVIQIDAETGRVSRIGTTKEEEGLFFRKKVEMPTGPVLKIKEFTYTVTLHDL
HHCCCCCCCEEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEEEEECC
DVVNARAGGIFSLLFGGRMEINDEIRERVDQTVKQWVEEGKATLVPGVLFIDECHMLDIE
EEECCCCCCEEEHHHCCCCEECHHHHHHHHHHHHHHHHCCCCEEECCEEEECCCCEEEHH
AFSFLARAMESELAPILILATNRGMTKIRGTDIESPHGIPLDMLDRLLIINTEPYKKEEI
HHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCCCCCHHHH
REIVKIRAREEKIELSEEALEYLAELGEQTSLRYAVQLLAPASIIAGGKRVEKEHVEKAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
EYFADVKRSIAFVEKVEGMLK
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVIEEIPTVKFERVGMHSHIKGLGLDENGKAKFIGDGMVGQVKAREAAGIAVKLIKQGK
CCCHHCCCCCHHHCCCHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHCCHHHEEHHCCC
LAGKGILLVGPTGSGKTAIAMGIARELGEDVPFVQISGSEIYSAEMKKTEFLKQALRRAI
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
GVRISEERKVYEGKVEKIEIRRTRHPFNPYIEIPESVVLTLKTKDDSKTIRAGREIAYQI
CCEECCCCHHHCCCCEEEEEECCCCCCCCCEECCCEEEEEEEECCCCHHHHHHHHHHHHH
LEMGIEEGDVIQIDAETGRVSRIGTTKEEEGLFFRKKVEMPTGPVLKIKEFTYTVTLHDL
HHCCCCCCCEEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEEEEECC
DVVNARAGGIFSLLFGGRMEINDEIRERVDQTVKQWVEEGKATLVPGVLFIDECHMLDIE
EEECCCCCCEEEHHHCCCCEECHHHHHHHHHHHHHHHHCCCCEEECCEEEECCCCEEEHH
AFSFLARAMESELAPILILATNRGMTKIRGTDIESPHGIPLDMLDRLLIINTEPYKKEEI
HHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCCCCCHHHH
REIVKIRAREEKIELSEEALEYLAELGEQTSLRYAVQLLAPASIIAGGKRVEKEHVEKAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
EYFADVKRSIAFVEKVEGMLK
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA