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The map label for this gene is ttdA [C]

Identifier: 18978127

GI number: 18978127

Start: 1632493

End: 1633311

Strand: Reverse

Name: ttdA [C]

Synonym: PF1755

Alternate gene names: 18978127

Gene position: 1633311-1632493 (Counterclockwise)

Preceding gene: 33359573

Following gene: 18978126

Centisome position: 85.59

GC content: 41.51

Gene sequence:

>819_bases
GTGGAGGACATAGTGGAAGCCCTTAAGCTCGCAGTTACAAACCTTCCTGAGGATGTAGCTTTGGCACTAAAGAATGCCTA
TGAAAGGGAAGACTACGAAATAGCAAAATATAACCTAGAAATAATGCTTAGAGCTGTAAAAACATCGAAAAAAGAAAAGG
TTCCTCTCTGTCAAGATACTGGAACTCCGATCTTCTTTGTTGAAACAGATGGAACTTGGAACGTTAAGGAGATCTATGAA
ACTATAGCTGAAGCTGTAAAAAGGGCGACAGATGAAATACCTCTAAGACCAAATGCAATTTGTCTCCTTTCGGGAAAAGT
TGTGGGAAATGTGCCAGAAATTCATATTGAACCTGGGAAAAGAAACAGAATTAGCATACTCATTAAAGGAGGTGGAAGTG
AAAATTGCTCTGCACTATTTCCTTTAACCCCCGGGGACTGGTTTGAAGGAGTAAAGAAGAAAATTATTGATCACATTAGA
TCGTGTGGCGGAAAGCCTTGCCCTCCTATAATTGTTGGCATTGGAATTGCAAGTCCTGCTGAAAGAGCTATAACTTTGGC
CAAGAAATCGCTCTTCAGAAAAATTGGCGAGAGGCATGAAAAGTTAGGATGGCTGGAAGAGGAAATTCTGGAGGAGATAA
ACTTCTTGGATATAGGTCCCATGGGATTGGGAGGGAAGACAACGGCATTAGATGTGAAAATTGAAGTGGGAGAAAGACAC
CCTGCGAGTTTTATAGTTGGGATTGCCATCCAATGTTGGGCACATAGAAGGGCATTTATTGAAGAGAAAGAAGATGGGGA
GGTCGTGATATGGCAGTAA

Upstream 100 bases:

>100_bases
AAAATTTTAGTTCTATATGTTGTGGAAATTGAAGGGGAAGTTGAGAAGTTCTTAGAAGAGTTAAGCAAAGCTAGGGCGGG
GGGATAGGTAATTGATCAAA

Downstream 100 bases:

>100_bases
GGCTAAAAACTCCCTTAACCTGGGAAGATATTAGGGATTTGGAAATTGGAGATAGAGTTCTTCTTTCTGGAATCGTTTAC
ACTGCTAGGGATCTAGCTCA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MEDIVEALKLAVTNLPEDVALALKNAYEREDYEIAKYNLEIMLRAVKTSKKEKVPLCQDTGTPIFFVETDGTWNVKEIYE
TIAEAVKRATDEIPLRPNAICLLSGKVVGNVPEIHIEPGKRNRISILIKGGGSENCSALFPLTPGDWFEGVKKKIIDHIR
SCGGKPCPPIIVGIGIASPAERAITLAKKSLFRKIGERHEKLGWLEEEILEEINFLDIGPMGLGGKTTALDVKIEVGERH
PASFIVGIAIQCWAHRRAFIEEKEDGEVVIWQ

Sequences:

>Translated_272_residues
MEDIVEALKLAVTNLPEDVALALKNAYEREDYEIAKYNLEIMLRAVKTSKKEKVPLCQDTGTPIFFVETDGTWNVKEIYE
TIAEAVKRATDEIPLRPNAICLLSGKVVGNVPEIHIEPGKRNRISILIKGGGSENCSALFPLTPGDWFEGVKKKIIDHIR
SCGGKPCPPIIVGIGIASPAERAITLAKKSLFRKIGERHEKLGWLEEEILEEINFLDIGPMGLGGKTTALDVKIEVGERH
PASFIVGIAIQCWAHRRAFIEEKEDGEVVIWQ
>Mature_272_residues
MEDIVEALKLAVTNLPEDVALALKNAYEREDYEIAKYNLEIMLRAVKTSKKEKVPLCQDTGTPIFFVETDGTWNVKEIYE
TIAEAVKRATDEIPLRPNAICLLSGKVVGNVPEIHIEPGKRNRISILIKGGGSENCSALFPLTPGDWFEGVKKKIIDHIR
SCGGKPCPPIIVGIGIASPAERAITLAKKSLFRKIGERHEKLGWLEEEILEEINFLDIGPMGLGGKTTALDVKIEVGERH
PASFIVGIAIQCWAHRRAFIEEKEDGEVVIWQ

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=264, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790564, Length=284, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787897, Length=284, Percent_Identity=25.7042253521127, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30176; Mature: 30176

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIVEALKLAVTNLPEDVALALKNAYEREDYEIAKYNLEIMLRAVKTSKKEKVPLCQDT
CHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCC
GTPIFFVETDGTWNVKEIYETIAEAVKRATDEIPLRPNAICLLSGKVVGNVPEIHIEPGK
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEECCCCEEEECCCC
RNRISILIKGGGSENCSALFPLTPGDWFEGVKKKIIDHIRSCGGKPCPPIIVGIGIASPA
CCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHH
ERAITLAKKSLFRKIGERHEKLGWLEEEILEEINFLDIGPMGLGGKTTALDVKIEVGERH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCCCCCCEEEEEEEEECCCC
PASFIVGIAIQCWAHRRAFIEEKEDGEVVIWQ
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
>Mature Secondary Structure
MEDIVEALKLAVTNLPEDVALALKNAYEREDYEIAKYNLEIMLRAVKTSKKEKVPLCQDT
CHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCC
GTPIFFVETDGTWNVKEIYETIAEAVKRATDEIPLRPNAICLLSGKVVGNVPEIHIEPGK
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEECCCCEEEECCCC
RNRISILIKGGGSENCSALFPLTPGDWFEGVKKKIIDHIRSCGGKPCPPIIVGIGIASPA
CCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHH
ERAITLAKKSLFRKIGERHEKLGWLEEEILEEINFLDIGPMGLGGKTTALDVKIEVGERH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCCCCCCEEEEEEEEECCCC
PASFIVGIAIQCWAHRRAFIEEKEDGEVVIWQ
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]