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The map label for this gene is ttdB [H]

Identifier: 18978126

GI number: 18978126

Start: 1632002

End: 1632502

Strand: Reverse

Name: ttdB [H]

Synonym: PF1754

Alternate gene names: 18978126

Gene position: 1632502-1632002 (Counterclockwise)

Preceding gene: 18978127

Following gene: 18978123

Centisome position: 85.55

GC content: 42.12

Gene sequence:

>501_bases
ATGGCAGTAAGGCTAAAAACTCCCTTAACCTGGGAAGATATTAGGGATTTGGAAATTGGAGATAGAGTTCTTCTTTCTGG
AATCGTTTACACTGCTAGGGATCTAGCTCATAGGAGATTTCTTGAAGAAGGCTTCCCTTTCAACCCTGAAGGTGCCGTGA
TATATCATTGCGGCCCTTTAATTAAAAATGGCATTGTAGTTTCGGCAGGCCCAACCACAAGTGCTAGGATGGAAAAGTAC
CTAGATTTCCTATTCAATCGCGGAGTTAGAGGGGTGATAGGGAAAGGGGGCATGAATCATGAGAAATTTAAAGGTAGGGC
AGTGTACTTTTCTTACCCAGGAGGAGCTGGTAGCTTAGCTAGGGAATTTATAGTTAAGGTGAGAGACGTCTATTGGGAAG
ATTTGGGAATGACTGATGCAGTTTGGGAATTAGAAGTGAGAGACATGCCTCTACTAGTCTCTATAGATTCAAAGGGAAGA
TCCCTATACAGAAAAAATTAA

Upstream 100 bases:

>100_bases
GAGAAAGACACCCTGCGAGTTTTATAGTTGGGATTGCCATCCAATGTTGGGCACATAGAAGGGCATTTATTGAAGAGAAA
GAAGATGGGGAGGTCGTGAT

Downstream 100 bases:

>100_bases
AGGGAGAAAAATCATTTGTGGGCATATATTGCGATAACTTTGTCGTTTTCTATTTTGTCAATCCTTACAAATCCAAATCT
TTCAAACTGCACTATTTCTC

Product: fumarate hydratase

Products: NA

Alternate protein names: L-TTD beta [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAVRLKTPLTWEDIRDLEIGDRVLLSGIVYTARDLAHRRFLEEGFPFNPEGAVIYHCGPLIKNGIVVSAGPTTSARMEKY
LDFLFNRGVRGVIGKGGMNHEKFKGRAVYFSYPGGAGSLAREFIVKVRDVYWEDLGMTDAVWELEVRDMPLLVSIDSKGR
SLYRKN

Sequences:

>Translated_166_residues
MAVRLKTPLTWEDIRDLEIGDRVLLSGIVYTARDLAHRRFLEEGFPFNPEGAVIYHCGPLIKNGIVVSAGPTTSARMEKY
LDFLFNRGVRGVIGKGGMNHEKFKGRAVYFSYPGGAGSLAREFIVKVRDVYWEDLGMTDAVWELEVRDMPLLVSIDSKGR
SLYRKN
>Mature_165_residues
AVRLKTPLTWEDIRDLEIGDRVLLSGIVYTARDLAHRRFLEEGFPFNPEGAVIYHCGPLIKNGIVVSAGPTTSARMEKYL
DFLFNRGVRGVIGKGGMNHEKFKGRAVYFSYPGGAGSLAREFIVKVRDVYWEDLGMTDAVWELEVRDMPLLVSIDSKGRS
LYRKN

Specific function: Unknown

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789443, Length=176, Percent_Identity=39.2045454545455, Blast_Score=125, Evalue=1e-30,
Organism=Escherichia coli, GI1787897, Length=160, Percent_Identity=31.25, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790564, Length=160, Percent_Identity=28.75, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004647 [H]

Pfam domain/function: PF05683 Fumerase_C [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 18742; Mature: 18611

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRLKTPLTWEDIRDLEIGDRVLLSGIVYTARDLAHRRFLEEGFPFNPEGAVIYHCGPL
CEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHH
IKNGIVVSAGPTTSARMEKYLDFLFNRGVRGVIGKGGMNHEKFKGRAVYFSYPGGAGSLA
HHCCEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCHHHH
REFIVKVRDVYWEDLGMTDAVWELEVRDMPLLVSIDSKGRSLYRKN
HHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AVRLKTPLTWEDIRDLEIGDRVLLSGIVYTARDLAHRRFLEEGFPFNPEGAVIYHCGPL
EEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHH
IKNGIVVSAGPTTSARMEKYLDFLFNRGVRGVIGKGGMNHEKFKGRAVYFSYPGGAGSLA
HHCCEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCHHHH
REFIVKVRDVYWEDLGMTDAVWELEVRDMPLLVSIDSKGRSLYRKN
HHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]