Click here to switch to the map view.

The map label for this gene is carB

Identifier: 18978086

GI number: 18978086

Start: 1591787

End: 1594957

Strand: Direct

Name: carB

Synonym: PF1714

Alternate gene names: 18978086

Gene position: 1591787-1594957 (Clockwise)

Preceding gene: 18978085

Following gene: 18978091

Centisome position: 83.42

GC content: 40.68

Gene sequence:

>3171_bases
ATGAAAATCGATGTATCAAAAGTCATTGTTATTGGTTCCGGTGCAATAAAAATAGGTGAAGCAGCTGAGTTTGACTACAG
TGGAAGTCAAGCATTAAAAGCATTAAGGGAAGAAGGGATAGAATCAGTGCTAGTAAATCCAAATGTTGCAACTATTCAAA
CTAGCTATGAGCTGGCAGACAAGGTTTATCTTCTTCCATTGAAAACCGAGTTCATAGAAAAGGTAATTGAAAAGGAAAAG
CCTGATGGAATACTAGTCGGTTTTGGAGGACAGACTGCACTCTCCCTGGGAGTTTCCTTGTACAAAAAGGGTATATTAGA
CAAATACAACGTAAAGGTCCTAGGAACTCCAATTGAAGGCATTGAAAGAGCACTCGACAGGGAGAAGTTTCAAAAGACCA
TGAAAAAAGTAGGCCTACCAGTTCCCCCAAGCGATGCAGCAAAAACTCCAGAGGAAGCCATCGAAATTGCTGAAAGCATA
GGATTTCCAGTAATAGTAAGAGTAAGCTTCAACTTAGGAGGCAGAGGCTCTTTCATAGCTAGGTCCAGAGAAGAGTTTGA
GAAATATATCATAAGAGCCTTTGCTCAAAGCGAAATAAGGAAAGTTCTCGTGGAGAAGTATCTCAACGGATGGAAAGAGA
TAGAGTTCGAAGTTGTTAGGGATAAAGCTGGAAACTCAGTTGCTGTTGTATGTTTAGAGAACGTTGATCCAATGGGAGTT
CACACAGGAGAATCAATAGTTGTAGGCCCTTCCCAAACCCTGACCAACAGGGAGTATCAAATGCTGAGGGACGCTGCAAT
AAGGGTTGCGGACGCAATAGAGTTAATTGGAGAAGGAAATGTCCAGCTCGCGTTAAGTCCCAACTCAGAGGAATACTATG
TTATCGAAACAAATCCCAGGATGAGTAGGTCGTCGGCACTAGCAAGCAAAGTTACTGGATACCCTCTCGCATACATAGCT
ACAAAGTTAGCAATAGGATACACCCTAGATGAACTAAGAAACACTGTTACAGGGATCACAACAGCAGCCTTTGAGCCAAG
TCTTGACTATGTAGCTGTTAAAATTCCCAGGTGGGATTTTAAGAAGTTTGAGGAGGTTAACAAGAGCATAGGAAGTGAAA
TGAAGAGCATAGGAGAAGTTATGGCAATCGGAAGGAACTTGCATGAAGCGTTTCAAAAGGCAATAAGAATGCTTGACATA
GGTGATGAGCTCATTGGAAAATACTACTTGGAAGATGAGCCTCTCGAGAATGTCCTAGAGAGACTAAAGAAAAAAGAACC
ATACTTATTGATGCACATAGCCAAGGCCCTTAGGCTCGGAGCTACGGTTGAAGATATCCACAAGATAACAAAAGTTGACA
AGTTCTTTATCTATGTAATAGAAGACCTTGTTAAGATAGCAGAGGAATTAAGGAAGAATCCAACAGAGGAACTTATTAGG
GAAGCTAAAAGGCTTGGATTCAGCGATTGGGAGATTGAGCTCCTAACAAAAAGAAAAGTAAAAAAGAAATGGAAGCCAGT
GGTTAAGAACATTGACACGTTGGCTGGAGAATTTCCAGCAAAAACAAACTACCTATATGTTACGTATGATGGTGTTGAAA
ACGACATTCCAAAACCAAAGAAACCCAGCATTCTAGTCTTGGGAGCAGGAGTGTTTAGGATAGGGGTAAGTGTTGAGTTC
GATTGGGCAGTTGTTAACTTTGTAAATGCCATAAGGAAGAGGGGAATAGAAGCAGCAATTCTAAACTACAACCCAGAAAC
AGTGTCAACTGATTGGGACATGAGTGATAGACTATACTTTGAGGAAATAACACTTGAGAGAGTTCTTGATATATATGAAT
TTGAAAGACCCATAGGCGTAGTGGCATTTGCAGGCGGCCAATTAGCTAATTCTCTAGCAAAGAAATTAGAAAATGCTGGA
GTGAAGCTACTCGGAACTTCAGGAAAGAGTGTGGATAAGGCAGAGAATAGGGCTAAGTTTTCAAAGTTATTAGAGAAGCT
CGGAATTCCTCAACCAGAATGGATCTCAGCAGAGAGCATTGATGAGGCTATAAAACTTGCAAAGAAAATTGAATACCCAG
TCATAGTGAGGCCAAGCTACGTCTTAAGTGGAACAGCAATGAAAGTTGCTTGGAATGAGAAAGAGCTAATAGACTTCTTA
AAAGAAGCTGCTTCAGTTTCACCTGAACATCCAGTTTTAATATCCAAGTTTATCCCAGGAACAGAAGCTGAGATTGACGC
TGTTAGCGATGGAAAGAAAGTTGTTGGAGTAACACTCGAGCATATCGAAGGTGCAGGGGTTCACAGTGGGGATTCAACAA
TGGTAACCCCGTGGAGAACTTTAAGTGAACGAAACGTGAAGAGAATATGGGAAATAACATACGAGCTTGCCAAAGAGTTA
GAAATTAAGGGACCCTTCAATGTTCAGTTCGTGATAGACAAAAAGCCCTACGTCCTAGAACTTAACCTAAGGACTAGCAG
GTCAATGCCATTCTCCAGTAAGTCCAGAGGAGTAAATCTAATGGAGTTATCTGCCCAGGCAGTGCTAGATGGAGAGTTAA
AAATTGGAGTTGAAGGGAAATATTATGAGATCCCACCTGTAGCCTATGGAGTAAAGAGTCCACAGTTCTCCTGGGCCCAA
CTCCAGGGAGCATATCCATTCCTCGGCCCAGAAATGAGATCAACAGGAGAGGTTGCGGCCCTGGGAACACATTACGAAGA
CGCCTTACTGAAAAGCTGGCTCTCAGTAAAGCCGAATGAACTTCCAAAGACATCCGCTTTAATCTATGGTTGGGAGAAAA
AAAATATCCTAAAAGAAACGGCAAAAATTTTAGAGAACCTCGGAATTACAACATATTCAATTGGTGGAGACATTGGAGAA
ATTAATATTTCAAAACAAGAGGCAGTTAATATGATCAAAGAAGGAAAAATAGATATTATAATGACCACAGGATATGCAAA
AGATAAGGATTATGAAATTAGAAGGCTTGCAGCAGATTTAAATGTTCCCTTGGTCTTAGATGCAAACTTAGCTTTGGAGC
TAGCAAAGGCTATAGAGTGGAAAACAAAAACTCAAGAAGAGTTTGAAATCAAAGAACTGAGAGAATACTGGATCAGAAAA
ATCGAAGAAAATGTTGAAGAATATGCAGCTTCAGTAGTTTTAAGGAGATAA

Upstream 100 bases:

>100_bases
TACCTATTATAGCTACCCAATATCATCCCGAGGCTTCTCCTGGCCCCTGGGATTCATTGTGGGTTTTTGATGAATTTGTA
AAGATTTTGGAGGGGAGAAA

Downstream 100 bases:

>100_bases
CCTTGTGGATAAGATCTTTGATTTTTTAGTTGCTGCATCAATGGCTTTCATTATTGTTGTTCTAATTTTTCCTTCCTCCA
ACTCAAATATCCCATCTATC

Product: carbamoyl phosphate synthase large subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase ammonia chain

Number of amino acids: Translated: 1056; Mature: 1056

Protein sequence:

>1056_residues
MKIDVSKVIVIGSGAIKIGEAAEFDYSGSQALKALREEGIESVLVNPNVATIQTSYELADKVYLLPLKTEFIEKVIEKEK
PDGILVGFGGQTALSLGVSLYKKGILDKYNVKVLGTPIEGIERALDREKFQKTMKKVGLPVPPSDAAKTPEEAIEIAESI
GFPVIVRVSFNLGGRGSFIARSREEFEKYIIRAFAQSEIRKVLVEKYLNGWKEIEFEVVRDKAGNSVAVVCLENVDPMGV
HTGESIVVGPSQTLTNREYQMLRDAAIRVADAIELIGEGNVQLALSPNSEEYYVIETNPRMSRSSALASKVTGYPLAYIA
TKLAIGYTLDELRNTVTGITTAAFEPSLDYVAVKIPRWDFKKFEEVNKSIGSEMKSIGEVMAIGRNLHEAFQKAIRMLDI
GDELIGKYYLEDEPLENVLERLKKKEPYLLMHIAKALRLGATVEDIHKITKVDKFFIYVIEDLVKIAEELRKNPTEELIR
EAKRLGFSDWEIELLTKRKVKKKWKPVVKNIDTLAGEFPAKTNYLYVTYDGVENDIPKPKKPSILVLGAGVFRIGVSVEF
DWAVVNFVNAIRKRGIEAAILNYNPETVSTDWDMSDRLYFEEITLERVLDIYEFERPIGVVAFAGGQLANSLAKKLENAG
VKLLGTSGKSVDKAENRAKFSKLLEKLGIPQPEWISAESIDEAIKLAKKIEYPVIVRPSYVLSGTAMKVAWNEKELIDFL
KEAASVSPEHPVLISKFIPGTEAEIDAVSDGKKVVGVTLEHIEGAGVHSGDSTMVTPWRTLSERNVKRIWEITYELAKEL
EIKGPFNVQFVIDKKPYVLELNLRTSRSMPFSSKSRGVNLMELSAQAVLDGELKIGVEGKYYEIPPVAYGVKSPQFSWAQ
LQGAYPFLGPEMRSTGEVAALGTHYEDALLKSWLSVKPNELPKTSALIYGWEKKNILKETAKILENLGITTYSIGGDIGE
INISKQEAVNMIKEGKIDIIMTTGYAKDKDYEIRRLAADLNVPLVLDANLALELAKAIEWKTKTQEEFEIKELREYWIRK
IEENVEEYAASVVLRR

Sequences:

>Translated_1056_residues
MKIDVSKVIVIGSGAIKIGEAAEFDYSGSQALKALREEGIESVLVNPNVATIQTSYELADKVYLLPLKTEFIEKVIEKEK
PDGILVGFGGQTALSLGVSLYKKGILDKYNVKVLGTPIEGIERALDREKFQKTMKKVGLPVPPSDAAKTPEEAIEIAESI
GFPVIVRVSFNLGGRGSFIARSREEFEKYIIRAFAQSEIRKVLVEKYLNGWKEIEFEVVRDKAGNSVAVVCLENVDPMGV
HTGESIVVGPSQTLTNREYQMLRDAAIRVADAIELIGEGNVQLALSPNSEEYYVIETNPRMSRSSALASKVTGYPLAYIA
TKLAIGYTLDELRNTVTGITTAAFEPSLDYVAVKIPRWDFKKFEEVNKSIGSEMKSIGEVMAIGRNLHEAFQKAIRMLDI
GDELIGKYYLEDEPLENVLERLKKKEPYLLMHIAKALRLGATVEDIHKITKVDKFFIYVIEDLVKIAEELRKNPTEELIR
EAKRLGFSDWEIELLTKRKVKKKWKPVVKNIDTLAGEFPAKTNYLYVTYDGVENDIPKPKKPSILVLGAGVFRIGVSVEF
DWAVVNFVNAIRKRGIEAAILNYNPETVSTDWDMSDRLYFEEITLERVLDIYEFERPIGVVAFAGGQLANSLAKKLENAG
VKLLGTSGKSVDKAENRAKFSKLLEKLGIPQPEWISAESIDEAIKLAKKIEYPVIVRPSYVLSGTAMKVAWNEKELIDFL
KEAASVSPEHPVLISKFIPGTEAEIDAVSDGKKVVGVTLEHIEGAGVHSGDSTMVTPWRTLSERNVKRIWEITYELAKEL
EIKGPFNVQFVIDKKPYVLELNLRTSRSMPFSSKSRGVNLMELSAQAVLDGELKIGVEGKYYEIPPVAYGVKSPQFSWAQ
LQGAYPFLGPEMRSTGEVAALGTHYEDALLKSWLSVKPNELPKTSALIYGWEKKNILKETAKILENLGITTYSIGGDIGE
INISKQEAVNMIKEGKIDIIMTTGYAKDKDYEIRRLAADLNVPLVLDANLALELAKAIEWKTKTQEEFEIKELREYWIRK
IEENVEEYAASVVLRR
>Mature_1056_residues
MKIDVSKVIVIGSGAIKIGEAAEFDYSGSQALKALREEGIESVLVNPNVATIQTSYELADKVYLLPLKTEFIEKVIEKEK
PDGILVGFGGQTALSLGVSLYKKGILDKYNVKVLGTPIEGIERALDREKFQKTMKKVGLPVPPSDAAKTPEEAIEIAESI
GFPVIVRVSFNLGGRGSFIARSREEFEKYIIRAFAQSEIRKVLVEKYLNGWKEIEFEVVRDKAGNSVAVVCLENVDPMGV
HTGESIVVGPSQTLTNREYQMLRDAAIRVADAIELIGEGNVQLALSPNSEEYYVIETNPRMSRSSALASKVTGYPLAYIA
TKLAIGYTLDELRNTVTGITTAAFEPSLDYVAVKIPRWDFKKFEEVNKSIGSEMKSIGEVMAIGRNLHEAFQKAIRMLDI
GDELIGKYYLEDEPLENVLERLKKKEPYLLMHIAKALRLGATVEDIHKITKVDKFFIYVIEDLVKIAEELRKNPTEELIR
EAKRLGFSDWEIELLTKRKVKKKWKPVVKNIDTLAGEFPAKTNYLYVTYDGVENDIPKPKKPSILVLGAGVFRIGVSVEF
DWAVVNFVNAIRKRGIEAAILNYNPETVSTDWDMSDRLYFEEITLERVLDIYEFERPIGVVAFAGGQLANSLAKKLENAG
VKLLGTSGKSVDKAENRAKFSKLLEKLGIPQPEWISAESIDEAIKLAKKIEYPVIVRPSYVLSGTAMKVAWNEKELIDFL
KEAASVSPEHPVLISKFIPGTEAEIDAVSDGKKVVGVTLEHIEGAGVHSGDSTMVTPWRTLSERNVKRIWEITYELAKEL
EIKGPFNVQFVIDKKPYVLELNLRTSRSMPFSSKSRGVNLMELSAQAVLDGELKIGVEGKYYEIPPVAYGVKSPQFSWAQ
LQGAYPFLGPEMRSTGEVAALGTHYEDALLKSWLSVKPNELPKTSALIYGWEKKNILKETAKILENLGITTYSIGGDIGE
INISKQEAVNMIKEGKIDIIMTTGYAKDKDYEIRRLAADLNVPLVLDANLALELAKAIEWKTKTQEEFEIKELREYWIRK
IEENVEEYAASVVLRR

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0458

COG function: function code EF; Carbamoylphosphate synthase large subunit (split gene in MJ)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ATP-grasp domains

Homologues:

Organism=Homo sapiens, GI18105007, Length=1057, Percent_Identity=46.8306527909177, Blast_Score=917, Evalue=0.0,
Organism=Homo sapiens, GI169790915, Length=1087, Percent_Identity=43.0542778288868, Blast_Score=853, Evalue=0.0,
Organism=Homo sapiens, GI21361331, Length=1087, Percent_Identity=43.0542778288868, Blast_Score=853, Evalue=0.0,
Organism=Homo sapiens, GI170295797, Length=1054, Percent_Identity=42.4098671726755, Blast_Score=809, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=373, Percent_Identity=21.4477211796247, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1786216, Length=1002, Percent_Identity=42.5149700598802, Blast_Score=771, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193204318, Length=1075, Percent_Identity=45.0232558139535, Blast_Score=879, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6322569, Length=1085, Percent_Identity=44.7004608294931, Blast_Score=864, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6322331, Length=1065, Percent_Identity=45.1643192488263, Blast_Score=848, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323863, Length=182, Percent_Identity=24.7252747252747, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319695, Length=282, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24642586, Length=1053, Percent_Identity=45.2041785375119, Blast_Score=878, Evalue=0.0,
Organism=Drosophila melanogaster, GI45555749, Length=985, Percent_Identity=46.5989847715736, Blast_Score=870, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652224, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652222, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652220, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652218, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652212, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652210, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652214, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19921944, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652216, Length=348, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24651757, Length=341, Percent_Identity=22.5806451612903, Blast_Score=67, Evalue=8e-11,

Paralogues:

None

Copy number: 4701 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CARB_PYRFU (Q8U085)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579443.1
- ProteinModelPortal:   Q8U085
- EnsemblBacteria:   EBPYRT00000004265
- GeneID:   1469591
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1714
- NMPDR:   fig|186497.1.peg.1762
- HOGENOM:   HBG405439
- OMA:   EFATNTA
- ProtClustDB:   PRK05294
- BRENDA:   6.3.5.5
- HAMAP:   MF_01210_A
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR006275
- InterPro:   IPR005479
- InterPro:   IPR005483
- InterPro:   IPR005481
- InterPro:   IPR005480
- InterPro:   IPR011607
- InterPro:   IPR013817
- InterPro:   IPR016185
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:1.10.1030.10
- Gene3D:   G3DSA:3.40.50.1380
- Gene3D:   G3DSA:3.40.50.20
- PRINTS:   PR00098
- TIGRFAMs:   TIGR01369

Pfam domain/function: PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF02787 CPSase_L_D3; SSF48108 CarbamoylP_synth_lsu_oligo; SSF52335 MGS-like_dom; SSF52440 PreATP-grasp-like

EC number: =6.3.5.5

Molecular weight: Translated: 118059; Mature: 118059

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50975 ATP_GRASP; PS00866 CPSASE_1; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDVSKVIVIGSGAIKIGEAAEFDYSGSQALKALREEGIESVLVNPNVATIQTSYELAD
CEEEEEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHCC
KVYLLPLKTEFIEKVIEKEKPDGILVGFGGQTALSLGVSLYKKGILDKYNVKVLGTPIEG
CEEEEECCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
IERALDREKFQKTMKKVGLPVPPSDAAKTPEEAIEIAESIGFPVIVRVSFNLGGRGSFIA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
RSREEFEKYIIRAFAQSEIRKVLVEKYLNGWKEIEFEVVRDKAGNSVAVVCLENVDPMGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCEEEEEEECCCCCCCC
HTGESIVVGPSQTLTNREYQMLRDAAIRVADAIELIGEGNVQLALSPNSEEYYVIETNPR
CCCCEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCC
MSRSSALASKVTGYPLAYIATKLAIGYTLDELRNTVTGITTAAFEPSLDYVAVKIPRWDF
CCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCH
KKFEEVNKSIGSEMKSIGEVMAIGRNLHEAFQKAIRMLDIGDELIGKYYLEDEPLENVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
RLKKKEPYLLMHIAKALRLGATVEDIHKITKVDKFFIYVIEDLVKIAEELRKNPTEELIR
HHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EAKRLGFSDWEIELLTKRKVKKKWKPVVKNIDTLAGEFPAKTNYLYVTYDGVENDIPKPK
HHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCC
KPSILVLGAGVFRIGVSVEFDWAVVNFVNAIRKRGIEAAILNYNPETVSTDWDMSDRLYF
CCCEEEEECCEEEEEEEEEECHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCCCCCEEH
EEITLERVLDIYEFERPIGVVAFAGGQLANSLAKKLENAGVKLLGTSGKSVDKAENRAKF
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHH
SKLLEKLGIPQPEWISAESIDEAIKLAKKIEYPVIVRPSYVLSGTAMKVAWNEKELIDFL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCEEECCCEEEEECCHHHHHHHH
KEAASVSPEHPVLISKFIPGTEAEIDAVSDGKKVVGVTLEHIEGAGVHSGDSTMVTPWRT
HHHHCCCCCCCEEEEECCCCCCCCCEECCCCCEEEEEEEECCCCCCCCCCCCCEECCHHH
LSERNVKRIWEITYELAKELEIKGPFNVQFVIDKKPYVLELNLRTSRSMPFSSKSRGVNL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEE
MELSAQAVLDGELKIGVEGKYYEIPPVAYGVKSPQFSWAQLQGAYPFLGPEMRSTGEVAA
EEECHHHEECCCEEEECCCCEEECCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCCCEEE
LGTHYEDALLKSWLSVKPNELPKTSALIYGWEKKNILKETAKILENLGITTYSIGGDIGE
ECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEE
INISKQEAVNMIKEGKIDIIMTTGYAKDKDYEIRRLAADLNVPLVLDANLALELAKAIEW
EECCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
KTKTQEEFEIKELREYWIRKIEENVEEYAASVVLRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIDVSKVIVIGSGAIKIGEAAEFDYSGSQALKALREEGIESVLVNPNVATIQTSYELAD
CEEEEEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHCC
KVYLLPLKTEFIEKVIEKEKPDGILVGFGGQTALSLGVSLYKKGILDKYNVKVLGTPIEG
CEEEEECCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
IERALDREKFQKTMKKVGLPVPPSDAAKTPEEAIEIAESIGFPVIVRVSFNLGGRGSFIA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
RSREEFEKYIIRAFAQSEIRKVLVEKYLNGWKEIEFEVVRDKAGNSVAVVCLENVDPMGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCEEEEEEECCCCCCCC
HTGESIVVGPSQTLTNREYQMLRDAAIRVADAIELIGEGNVQLALSPNSEEYYVIETNPR
CCCCEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCC
MSRSSALASKVTGYPLAYIATKLAIGYTLDELRNTVTGITTAAFEPSLDYVAVKIPRWDF
CCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCH
KKFEEVNKSIGSEMKSIGEVMAIGRNLHEAFQKAIRMLDIGDELIGKYYLEDEPLENVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
RLKKKEPYLLMHIAKALRLGATVEDIHKITKVDKFFIYVIEDLVKIAEELRKNPTEELIR
HHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EAKRLGFSDWEIELLTKRKVKKKWKPVVKNIDTLAGEFPAKTNYLYVTYDGVENDIPKPK
HHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCC
KPSILVLGAGVFRIGVSVEFDWAVVNFVNAIRKRGIEAAILNYNPETVSTDWDMSDRLYF
CCCEEEEECCEEEEEEEEEECHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCCCCCEEH
EEITLERVLDIYEFERPIGVVAFAGGQLANSLAKKLENAGVKLLGTSGKSVDKAENRAKF
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHH
SKLLEKLGIPQPEWISAESIDEAIKLAKKIEYPVIVRPSYVLSGTAMKVAWNEKELIDFL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCEEECCCEEEEECCHHHHHHHH
KEAASVSPEHPVLISKFIPGTEAEIDAVSDGKKVVGVTLEHIEGAGVHSGDSTMVTPWRT
HHHHCCCCCCCEEEEECCCCCCCCCEECCCCCEEEEEEEECCCCCCCCCCCCCEECCHHH
LSERNVKRIWEITYELAKELEIKGPFNVQFVIDKKPYVLELNLRTSRSMPFSSKSRGVNL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEE
MELSAQAVLDGELKIGVEGKYYEIPPVAYGVKSPQFSWAQLQGAYPFLGPEMRSTGEVAA
EEECHHHEECCCEEEECCCCEEECCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCCCEEE
LGTHYEDALLKSWLSVKPNELPKTSALIYGWEKKNILKETAKILENLGITTYSIGGDIGE
ECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEE
INISKQEAVNMIKEGKIDIIMTTGYAKDKDYEIRRLAADLNVPLVLDANLALELAKAIEW
EECCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
KTKTQEEFEIKELREYWIRKIEENVEEYAASVVLRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA