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The map label for this gene is pmbA [C]

Identifier: 18977946

GI number: 18977946

Start: 1470356

End: 1471684

Strand: Direct

Name: pmbA [C]

Synonym: PF1574

Alternate gene names: 18977946

Gene position: 1470356-1471684 (Clockwise)

Preceding gene: 18977945

Following gene: 18977955

Centisome position: 77.05

GC content: 39.43

Gene sequence:

>1329_bases
ATGGAAGAACTAATTAGGTATGGAGAGAAATTTTTTGATGAACTAGAGATTGTAACAAGAGTAGGAAAGGATTTCAGCGT
TGATATTCAGCTTAATGAAGTCTTTGGTGGAGGCGTAAGAGAGGACATTCTAACAATAATTAGAGGTATAAAGGACAAAA
GAATTGGAATAGTTTTACTTGATACAATAGACAAAGAAGAGATCAAGAAAGGAATTGAAACTGCTGCTAAGATGGCAAAG
CTTAACGCTCCCGATGAAAAGTGGTCATCTCTCCCTCAACCAGGGAAATACAGAGAAAAACCAAAGATTAGTGAAGATTT
AAAGTCCGCCTCTTCCGATGAATTAGTTAACATGGCAGTGGAGGGAATAAAGTTAGCAAGGGAACTTGATAAAAATTTAA
CCGTTGCGGGGGGAAGCATTGGAACTTCATGGAATGAAATTACTATAGTGAACTCCCATGGCATAAACGTTACCCAAGAA
CTTGGAGTTGCCTATGCATTTTTTGAGTTCGTAGGAAGAAAAGAAGGTATTGTAACCCCAGGAATCTTTGAATTTGACGC
CAAGGACAACCTCAACTTGAACATCGAAGAAACAGTAAAGAACGGAGTCAAAAAAGTCCAGTGGGCTTATAACTTTAAAC
AAGCAAAAAATGAAGAAACAACCCTAATATTTGGCCCCTGGGCAATATCAGGATTGCTTAACTATGCCCTATTCCCAGCG
TTTAGTGGAGAAAGATTGGTTAAAGGCACAACTCCTCTTGCAGATAAAGTGGGAGAAAGAATTACAAGTGAAGTAATTAC
CCTTTACGACGACCCGTTCCACGAGTTAAGCATCACCAAAATAATCGCTGATGGGGAAGGAATACCAACAAGAAGGTATG
AGATTATCAAAGATGGTGAATTTAAGGGATTCATCTGGGACAACTACTGGGCAAAAGTCCACGGAACTGAAAGCACAGGA
CATGGAGTAAGAGATTGGAGCGGGGGTGGAATAACTATTGGTCTTCACGTTCCTATCATCGAGAATGGTAAGAGGAGCCT
TGAAGAGATCATCGGGGAAATTAAACATGGTTATTTAGTAGATGGCGTTCAAGGAGCACATTCAAGCAATCCAGATAATG
GCAACTTTGCAGTAACGGCAAATCCTGCTTACATAATTGAAAATGGTGAAATTGTTGGATCAACAGTGTTCTTAATAGCT
GGGAATATCTATGAATTGCTCAAAAAGGCTACAGAAGTTAGTAAGGAACAGAGAACTCTAGTAGGAATGACTAACGTCAT
TACCCCATACATAAAATTTGAAAACGTCAAGATAGCCGGAAAGAGTTGA

Upstream 100 bases:

>100_bases
AACAGGATTCTGTGGAAAGGGGCAAATTGCATTTGTGAGCTCTGGAGGTCCTCACATGAGATTTGACGGAGGAATTATTA
TTGGATGAGGAGGGTAAGAA

Downstream 100 bases:

>100_bases
CTTTTCCCTTTTTTACCATCATTATTCCCGTAAATAGCCCAAGAGTATCAGCAATAATATCCCTAATTTTATTTCCCAGG
GATTCTGTAATGAAAGAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MEELIRYGEKFFDELEIVTRVGKDFSVDIQLNEVFGGGVREDILTIIRGIKDKRIGIVLLDTIDKEEIKKGIETAAKMAK
LNAPDEKWSSLPQPGKYREKPKISEDLKSASSDELVNMAVEGIKLARELDKNLTVAGGSIGTSWNEITIVNSHGINVTQE
LGVAYAFFEFVGRKEGIVTPGIFEFDAKDNLNLNIEETVKNGVKKVQWAYNFKQAKNEETTLIFGPWAISGLLNYALFPA
FSGERLVKGTTPLADKVGERITSEVITLYDDPFHELSITKIIADGEGIPTRRYEIIKDGEFKGFIWDNYWAKVHGTESTG
HGVRDWSGGGITIGLHVPIIENGKRSLEEIIGEIKHGYLVDGVQGAHSSNPDNGNFAVTANPAYIIENGEIVGSTVFLIA
GNIYELLKKATEVSKEQRTLVGMTNVITPYIKFENVKIAGKS

Sequences:

>Translated_442_residues
MEELIRYGEKFFDELEIVTRVGKDFSVDIQLNEVFGGGVREDILTIIRGIKDKRIGIVLLDTIDKEEIKKGIETAAKMAK
LNAPDEKWSSLPQPGKYREKPKISEDLKSASSDELVNMAVEGIKLARELDKNLTVAGGSIGTSWNEITIVNSHGINVTQE
LGVAYAFFEFVGRKEGIVTPGIFEFDAKDNLNLNIEETVKNGVKKVQWAYNFKQAKNEETTLIFGPWAISGLLNYALFPA
FSGERLVKGTTPLADKVGERITSEVITLYDDPFHELSITKIIADGEGIPTRRYEIIKDGEFKGFIWDNYWAKVHGTESTG
HGVRDWSGGGITIGLHVPIIENGKRSLEEIIGEIKHGYLVDGVQGAHSSNPDNGNFAVTANPAYIIENGEIVGSTVFLIA
GNIYELLKKATEVSKEQRTLVGMTNVITPYIKFENVKIAGKS
>Mature_442_residues
MEELIRYGEKFFDELEIVTRVGKDFSVDIQLNEVFGGGVREDILTIIRGIKDKRIGIVLLDTIDKEEIKKGIETAAKMAK
LNAPDEKWSSLPQPGKYREKPKISEDLKSASSDELVNMAVEGIKLARELDKNLTVAGGSIGTSWNEITIVNSHGINVTQE
LGVAYAFFEFVGRKEGIVTPGIFEFDAKDNLNLNIEETVKNGVKKVQWAYNFKQAKNEETTLIFGPWAISGLLNYALFPA
FSGERLVKGTTPLADKVGERITSEVITLYDDPFHELSITKIIADGEGIPTRRYEIIKDGEFKGFIWDNYWAKVHGTESTG
HGVRDWSGGGITIGLHVPIIENGKRSLEEIIGEIKHGYLVDGVQGAHSSNPDNGNFAVTANPAYIIENGEIVGSTVFLIA
GNIYELLKKATEVSKEQRTLVGMTNVITPYIKFENVKIAGKS

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790682, Length=392, Percent_Identity=22.7040816326531, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789640, Length=426, Percent_Identity=21.5962441314554, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48842; Mature: 48842

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELIRYGEKFFDELEIVTRVGKDFSVDIQLNEVFGGGVREDILTIIRGIKDKRIGIVLL
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEE
DTIDKEEIKKGIETAAKMAKLNAPDEKWSSLPQPGKYREKPKISEDLKSASSDELVNMAV
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
EGIKLARELDKNLTVAGGSIGTSWNEITIVNSHGINVTQELGVAYAFFEFVGRKEGIVTP
HHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
GIFEFDAKDNLNLNIEETVKNGVKKVQWAYNFKQAKNEETTLIFGPWAISGLLNYALFPA
CEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECHHHHHHHHHHHHCCC
FSGERLVKGTTPLADKVGERITSEVITLYDDPFHELSITKIIADGEGIPTRRYEIIKDGE
CCCCEEECCCCCHHHHHHHHHHHHHHEECCCCCHHEEEEEEEECCCCCCCCCEEEEECCC
FKGFIWDNYWAKVHGTESTGHGVRDWSGGGITIGLHVPIIENGKRSLEEIIGEIKHGYLV
EEEEEECCEEEEEECCCCCCCCCCEECCCCEEEEEEEEEECCCHHHHHHHHHHHCCCEEE
DGVQGAHSSNPDNGNFAVTANPAYIIENGEIVGSTVFLIAGNIYELLKKATEVSKEQRTL
ECCCCCCCCCCCCCCEEEEECCEEEEECCEEECEEEEEECCCHHHHHHHHHHHHHHHHHH
VGMTNVITPYIKFENVKIAGKS
HHHHHHHCCEEEEEEEEEECCC
>Mature Secondary Structure
MEELIRYGEKFFDELEIVTRVGKDFSVDIQLNEVFGGGVREDILTIIRGIKDKRIGIVLL
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEE
DTIDKEEIKKGIETAAKMAKLNAPDEKWSSLPQPGKYREKPKISEDLKSASSDELVNMAV
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
EGIKLARELDKNLTVAGGSIGTSWNEITIVNSHGINVTQELGVAYAFFEFVGRKEGIVTP
HHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
GIFEFDAKDNLNLNIEETVKNGVKKVQWAYNFKQAKNEETTLIFGPWAISGLLNYALFPA
CEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECHHHHHHHHHHHHCCC
FSGERLVKGTTPLADKVGERITSEVITLYDDPFHELSITKIIADGEGIPTRRYEIIKDGE
CCCCEEECCCCCHHHHHHHHHHHHHHEECCCCCHHEEEEEEEECCCCCCCCCEEEEECCC
FKGFIWDNYWAKVHGTESTGHGVRDWSGGGITIGLHVPIIENGKRSLEEIIGEIKHGYLV
EEEEEECCEEEEEECCCCCCCCCCEECCCCEEEEEEEEEECCCHHHHHHHHHHHCCCEEE
DGVQGAHSSNPDNGNFAVTANPAYIIENGEIVGSTVFLIAGNIYELLKKATEVSKEQRTL
ECCCCCCCCCCCCCCEEEEECCEEEEECCEEECEEEEEECCCHHHHHHHHHHHHHHHHHH
VGMTNVITPYIKFENVKIAGKS
HHHHHHHCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]