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The map label for this gene is hflX [C]

Identifier: 18977549

GI number: 18977549

Start: 1123434

End: 1124729

Strand: Direct

Name: hflX [C]

Synonym: PF1177

Alternate gene names: 18977549

Gene position: 1123434-1124729 (Clockwise)

Preceding gene: 18977548

Following gene: 18977552

Centisome position: 58.87

GC content: 40.97

Gene sequence:

>1296_bases
ATGATGAGAGCAATTGGTGTTATTAGAAAATCTCGACAGGAGAGAATTAGTAGGGAAGAGTTTGAAGACCTTTTAAGGAG
TGCAGGTTATGAGATTCTTGCAATAGTTGAGCAGGTTAGAGAGGAACATCCCAGATATAATATAGGACCCGGGAAGGTTG
AAGAGCTTAAAAGTCTCGTCAAGGAACTCAAACCAGATAAGGTTGTTTTTGCCAATAAATTGACTCCTTCTCAAGCTTAC
AATCTTTGGAAAGAGCTAAGGGTTGATATAATTGATAAGTGGCAACTTGTCCTCGAAATATTTGAAAAGAGAGCTCATTC
CAAAGAGGCAAAGCTCCAAGTTGAGCTAGCTAACCTTCAGTATGAATTACCTCTCGTTAAGGAAGCAATACGAAGAATAA
AAATGGGTGATAGAGCTGGATTCAAGGGTATGGGTGAGTACCAGGTTCACCAATACTTTAAGCACATAAGATATAGAATG
GGAAAAATCAGAGAAGAGCTGGAGAAGATAAAGGCAGAGAGAGATATAAGAAGGAAGAAGAGAGAAGAGGACGGATTTGT
TCTAGTTGCCCTTGCTGGATATACAAATGCAGGAAAATCTACACTCCTAAACGCTTTGACTGGAGAAAACGTCGAAGCAA
AAAATCAGATGTTCACAACACTAGATACGACAACAAGGAGATTCAAGCTTGGAGGGAAGCTACTCCTCATTACCGACACT
GTCGGTTTTATCGACAATTTACCCCCTTTCATCGTTGAGGCATTCCACTCAACCCTAGAGGAGATAGTAAAGGCCGACAT
AATAGTTCTAGTCTTAGATTCAAGTGAAGCTTGGCCTGAAATAAGGAGGAAGTTCTTTGCATCTCTCAATGTCCTCAGAG
AGTTGAAGGCATTAGAAAGGCCAATGATAATAGCCCTTAACAAGATCGATAAAGTGACTCCCGAGGATGCCGAAACAAAG
AAAATGCTTCTAAAGGAGATAGCTGACGGAAGAGTAAACTTGGTTGAAGTTGTAAAGATCTCCGCAAAGAACGGAATTCT
TGAAGAGTTGTACACCGCTTTAGAGAAGGCTCTCCTAAAGCTACCTAAGTTCCAATTCTTTGAGATAGTTGTGAAGGACC
CCACCCAAGTTGGAAAGATTCTCTCTCTAGTTTACTCCGTAGGAGATGTCCTCGAGGTCACCTATAATGGAGGGGAAGAG
ACCACAATTAAGGCATATATGCAGAGCGGAATGATAAGAGAGTTAACAAAGCTGGGTGTAGAGATAAAGAGACTACAAAT
CAGAGAAGAAGCTTAA

Upstream 100 bases:

>100_bases
AAGTTAAAACTGCAAGAGAAGAGACAGAAGCTCTTTTAAGAAAGCCAAGGCCCCCGCTCTTAGTTGACAATGATTTATAA
ACCAAAAATATAAAGATGTA

Downstream 100 bases:

>100_bases
CTAAAACATAGGAAAGGCTCATAGAGAACAATGGAGCAACTACCCATCCAAGTGCAATATGTTGCACTGTCTTCTTCTTA
ATTCTCTCTCCAGTTGAAAG

Product: gtp1/obg family GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MMRAIGVIRKSRQERISREEFEDLLRSAGYEILAIVEQVREEHPRYNIGPGKVEELKSLVKELKPDKVVFANKLTPSQAY
NLWKELRVDIIDKWQLVLEIFEKRAHSKEAKLQVELANLQYELPLVKEAIRRIKMGDRAGFKGMGEYQVHQYFKHIRYRM
GKIREELEKIKAERDIRRKKREEDGFVLVALAGYTNAGKSTLLNALTGENVEAKNQMFTTLDTTTRRFKLGGKLLLITDT
VGFIDNLPPFIVEAFHSTLEEIVKADIIVLVLDSSEAWPEIRRKFFASLNVLRELKALERPMIIALNKIDKVTPEDAETK
KMLLKEIADGRVNLVEVVKISAKNGILEELYTALEKALLKLPKFQFFEIVVKDPTQVGKILSLVYSVGDVLEVTYNGGEE
TTIKAYMQSGMIRELTKLGVEIKRLQIREEA

Sequences:

>Translated_431_residues
MMRAIGVIRKSRQERISREEFEDLLRSAGYEILAIVEQVREEHPRYNIGPGKVEELKSLVKELKPDKVVFANKLTPSQAY
NLWKELRVDIIDKWQLVLEIFEKRAHSKEAKLQVELANLQYELPLVKEAIRRIKMGDRAGFKGMGEYQVHQYFKHIRYRM
GKIREELEKIKAERDIRRKKREEDGFVLVALAGYTNAGKSTLLNALTGENVEAKNQMFTTLDTTTRRFKLGGKLLLITDT
VGFIDNLPPFIVEAFHSTLEEIVKADIIVLVLDSSEAWPEIRRKFFASLNVLRELKALERPMIIALNKIDKVTPEDAETK
KMLLKEIADGRVNLVEVVKISAKNGILEELYTALEKALLKLPKFQFFEIVVKDPTQVGKILSLVYSVGDVLEVTYNGGEE
TTIKAYMQSGMIRELTKLGVEIKRLQIREEA
>Mature_431_residues
MMRAIGVIRKSRQERISREEFEDLLRSAGYEILAIVEQVREEHPRYNIGPGKVEELKSLVKELKPDKVVFANKLTPSQAY
NLWKELRVDIIDKWQLVLEIFEKRAHSKEAKLQVELANLQYELPLVKEAIRRIKMGDRAGFKGMGEYQVHQYFKHIRYRM
GKIREELEKIKAERDIRRKKREEDGFVLVALAGYTNAGKSTLLNALTGENVEAKNQMFTTLDTTTRRFKLGGKLLLITDT
VGFIDNLPPFIVEAFHSTLEEIVKADIIVLVLDSSEAWPEIRRKFFASLNVLRELKALERPMIIALNKIDKVTPEDAETK
KMLLKEIADGRVNLVEVVKISAKNGILEELYTALEKALLKLPKFQFFEIVVKDPTQVGKILSLVYSVGDVLEVTYNGGEE
TTIKAYMQSGMIRELTKLGVEIKRLQIREEA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=260, Percent_Identity=31.5384615384615, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310124267, Length=260, Percent_Identity=31.5384615384615, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310124171, Length=260, Percent_Identity=31.5384615384615, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310124169, Length=260, Percent_Identity=31.5384615384615, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310133118, Length=260, Percent_Identity=31.1538461538462, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310133116, Length=260, Percent_Identity=31.1538461538462, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1790615, Length=377, Percent_Identity=35.0132625994695, Blast_Score=181, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17561038, Length=341, Percent_Identity=28.7390029325513, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24650079, Length=328, Percent_Identity=34.4512195121951, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49545; Mature: 49545

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRAIGVIRKSRQERISREEFEDLLRSAGYEILAIVEQVREEHPRYNIGPGKVEELKSLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KELKPDKVVFANKLTPSQAYNLWKELRVDIIDKWQLVLEIFEKRAHSKEAKLQVELANLQ
HHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCE
YELPLVKEAIRRIKMGDRAGFKGMGEYQVHQYFKHIRYRMGKIREELEKIKAERDIRRKK
EECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REEDGFVLVALAGYTNAGKSTLLNALTGENVEAKNQMFTTLDTTTRRFKLGGKLLLITDT
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
VGFIDNLPPFIVEAFHSTLEEIVKADIIVLVLDSSEAWPEIRRKFFASLNVLRELKALER
HHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
PMIIALNKIDKVTPEDAETKKMLLKEIADGRVNLVEVVKISAKNGILEELYTALEKALLK
CCEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHHH
LPKFQFFEIVVKDPTQVGKILSLVYSVGDVLEVTYNGGEETTIKAYMQSGMIRELTKLGV
CCCHHHHHEEECCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHHHHHHHCH
EIKRLQIREEA
HHHHHHHCCCC
>Mature Secondary Structure
MMRAIGVIRKSRQERISREEFEDLLRSAGYEILAIVEQVREEHPRYNIGPGKVEELKSLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KELKPDKVVFANKLTPSQAYNLWKELRVDIIDKWQLVLEIFEKRAHSKEAKLQVELANLQ
HHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCE
YELPLVKEAIRRIKMGDRAGFKGMGEYQVHQYFKHIRYRMGKIREELEKIKAERDIRRKK
EECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REEDGFVLVALAGYTNAGKSTLLNALTGENVEAKNQMFTTLDTTTRRFKLGGKLLLITDT
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
VGFIDNLPPFIVEAFHSTLEEIVKADIIVLVLDSSEAWPEIRRKFFASLNVLRELKALER
HHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
PMIIALNKIDKVTPEDAETKKMLLKEIADGRVNLVEVVKISAKNGILEELYTALEKALLK
CCEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHHH
LPKFQFFEIVVKDPTQVGKILSLVYSVGDVLEVTYNGGEETTIKAYMQSGMIRELTKLGV
CCCHHHHHEEECCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHHHHHHHCH
EIKRLQIREEA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]