Click here to switch to the map view.

The map label for this gene is thrC [H]

Identifier: 18977552

GI number: 18977552

Start: 1125994

End: 1127145

Strand: Direct

Name: thrC [H]

Synonym: PF1180

Alternate gene names: 18977552

Gene position: 1125994-1127145 (Clockwise)

Preceding gene: 18977549

Following gene: 18977557

Centisome position: 59.01

GC content: 40.97

Gene sequence:

>1152_bases
ATGCTTAGGTGCACTTCATGTGGAAGAATGTATTCATTTGACAGCCCATATCAAAGGTGCGAATGTGGAGAGCCTTTGGA
ACTTGAGCTTTTCAATGGGATGTATAAAAAGAAAGGAAAGAGGGTATGGGAAAGGTTTTCTGAGTTCTTTCCTCTCGAAC
TAGATCCAGAGTTAAGCTTGGGAGAAGGAGATACTCCATTAACAAGAGCAAAGAAGCTTTCGAAAGAACTTGGAATTGAG
CTATATTTAAAAAACGAGACTATAAATCCCACGTGGAGTTTTAAAGATAGGGGAACCTACCTGGGAATTCATAGGGCGAT
ACAACTTGACTTTAGAAGGATTGGGACGGTATCAACGGGAAATATGGCGGCAAGTGTTGCCGCATATGGAGCTCATTCTG
AGCTCGAAGTTTACATTTTGGTTTCCTCAACAATACCAGAGGAAAAGATTAAGGCCTTAGCTCCCTATGGAGCAAAGATT
GTAAAGGTTCATGGGGACTATGGGGAACTCTATTATAGGGCCCTAGAAATAGGGCAGAAAAAGGGAATATATTTCATAAA
CTCGGATGATCCCTTTAGAGTTGAAGGGTATAAGAGCATAAGCTTCGAGATAAGTGAGGAGATAACTCCAGACTACGTAA
TAGTCCCTACGTCATCTGGAGGCCTATTTAGAGGTATTGTGAAGGGGTTTCTGGAAGCCAAGAATAGTGGACTAATAGAA
AAGCTCCCTAGATTTTTTGTGGTACAGGCTGAGGGCTGTTCTCCAATATGTAAAGCATTCAACGCTGGAAAAGAAAAGAT
AGAGAGATTTGAAAATCCCCATACAATCGCCCATGCAATAGAAAATCCATATCCTCCAAGTGGAAATGCAGTCCTAAGAT
TGCTGAAGAAATTGAATGGCATTTGTACCACGGTTACAGATGAAGAGATTCTAGAGGCCCAGAAAATCCTGGGAAGAGAA
GGAATTTTTGTTCAACTCGCATCTGCAACAGGAATAGCCGCAGTAAAAAAGCTAAGGCGAAAAGGAATTATCAAAGAAGG
AGCAATTGTAGTTAGCATTCTTACGGGCTCTGGATTAAAGACATTGAGGTACATTAAGCAACCAAAAGTCGAGGAATGCT
CTTTACAAAGATTAGAAGAGTGCATTGGATAA

Upstream 100 bases:

>100_bases
CTTATATACAAACTCCTTAGAGGTCATGGAAAAGACACCATACTAACTACAGCTTGGATATTAATTAATCTTTCTGGACA
AAAATGTTCAGGTGATTTAT

Downstream 100 bases:

>100_bases
AATCACTCAGCCTTTATATATAATCCCGTTGGCACTTGGACTGAACATGAGTTGAACAATCCTGCCTTGAAGGTGTAAGG
TTGAGAGCTCCTGAAGGCAT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLRCTSCGRMYSFDSPYQRCECGEPLELELFNGMYKKKGKRVWERFSEFFPLELDPELSLGEGDTPLTRAKKLSKELGIE
LYLKNETINPTWSFKDRGTYLGIHRAIQLDFRRIGTVSTGNMAASVAAYGAHSELEVYILVSSTIPEEKIKALAPYGAKI
VKVHGDYGELYYRALEIGQKKGIYFINSDDPFRVEGYKSISFEISEEITPDYVIVPTSSGGLFRGIVKGFLEAKNSGLIE
KLPRFFVVQAEGCSPICKAFNAGKEKIERFENPHTIAHAIENPYPPSGNAVLRLLKKLNGICTTVTDEEILEAQKILGRE
GIFVQLASATGIAAVKKLRRKGIIKEGAIVVSILTGSGLKTLRYIKQPKVEECSLQRLEECIG

Sequences:

>Translated_383_residues
MLRCTSCGRMYSFDSPYQRCECGEPLELELFNGMYKKKGKRVWERFSEFFPLELDPELSLGEGDTPLTRAKKLSKELGIE
LYLKNETINPTWSFKDRGTYLGIHRAIQLDFRRIGTVSTGNMAASVAAYGAHSELEVYILVSSTIPEEKIKALAPYGAKI
VKVHGDYGELYYRALEIGQKKGIYFINSDDPFRVEGYKSISFEISEEITPDYVIVPTSSGGLFRGIVKGFLEAKNSGLIE
KLPRFFVVQAEGCSPICKAFNAGKEKIERFENPHTIAHAIENPYPPSGNAVLRLLKKLNGICTTVTDEEILEAQKILGRE
GIFVQLASATGIAAVKKLRRKGIIKEGAIVVSILTGSGLKTLRYIKQPKVEECSLQRLEECIG
>Mature_383_residues
MLRCTSCGRMYSFDSPYQRCECGEPLELELFNGMYKKKGKRVWERFSEFFPLELDPELSLGEGDTPLTRAKKLSKELGIE
LYLKNETINPTWSFKDRGTYLGIHRAIQLDFRRIGTVSTGNMAASVAAYGAHSELEVYILVSSTIPEEKIKALAPYGAKI
VKVHGDYGELYYRALEIGQKKGIYFINSDDPFRVEGYKSISFEISEEITPDYVIVPTSSGGLFRGIVKGFLEAKNSGLIE
KLPRFFVVQAEGCSPICKAFNAGKEKIERFENPHTIAHAIENPYPPSGNAVLRLLKKLNGICTTVTDEEILEAQKILGRE
GIFVQLASATGIAAVKKLRRKGIIKEGAIVVSILTGSGLKTLRYIKQPKVEECSLQRLEECIG

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 42713; Mature: 42713

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRCTSCGRMYSFDSPYQRCECGEPLELELFNGMYKKKGKRVWERFSEFFPLELDPELSL
CCEECCCCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GEGDTPLTRAKKLSKELGIELYLKNETINPTWSFKDRGTYLGIHRAIQLDFRRIGTVSTG
CCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEHHHHEEHHHHCCCCCCC
NMAASVAAYGAHSELEVYILVSSTIPEEKIKALAPYGAKIVKVHGDYGELYYRALEIGQK
CHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCC
KGIYFINSDDPFRVEGYKSISFEISEEITPDYVIVPTSSGGLFRGIVKGFLEAKNSGLIE
CCEEEECCCCCEEEECCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHH
KLPRFFVVQAEGCSPICKAFNAGKEKIERFENPHTIAHAIENPYPPSGNAVLRLLKKLNG
HCCCEEEEEECCCCHHHHHHHCCHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCC
ICTTVTDEEILEAQKILGREGIFVQLASATGIAAVKKLRRKGIIKEGAIVVSILTGSGLK
CEEECCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHH
TLRYIKQPKVEECSLQRLEECIG
HHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRCTSCGRMYSFDSPYQRCECGEPLELELFNGMYKKKGKRVWERFSEFFPLELDPELSL
CCEECCCCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GEGDTPLTRAKKLSKELGIELYLKNETINPTWSFKDRGTYLGIHRAIQLDFRRIGTVSTG
CCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEHHHHEEHHHHCCCCCCC
NMAASVAAYGAHSELEVYILVSSTIPEEKIKALAPYGAKIVKVHGDYGELYYRALEIGQK
CHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCC
KGIYFINSDDPFRVEGYKSISFEISEEITPDYVIVPTSSGGLFRGIVKGFLEAKNSGLIE
CCEEEECCCCCEEEECCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHH
KLPRFFVVQAEGCSPICKAFNAGKEKIERFENPHTIAHAIENPYPPSGNAVLRLLKKLNG
HCCCEEEEEECCCCHHHHHHHCCHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCC
ICTTVTDEEILEAQKILGREGIFVQLASATGIAAVKKLRRKGIIKEGAIVVSILTGSGLK
CEEECCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHH
TLRYIKQPKVEECSLQRLEECIG
HHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]