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The map label for this gene is mrp [C]

Identifier: 18977517

GI number: 18977517

Start: 1098283

End: 1099170

Strand: Reverse

Name: mrp [C]

Synonym: PF1145

Alternate gene names: 18977517

Gene position: 1099170-1098283 (Counterclockwise)

Preceding gene: 18977519

Following gene: 18977516

Centisome position: 57.6

GC content: 45.83

Gene sequence:

>888_bases
GTGACGATAAAGGCCCCAACTTTGAACGTCCCTGGTCTTGGCGTTGATCCTCTGACTCAAAGAATCAAGGAGAAGGAGAA
GAAGTGGAAGTACAAAATAGCTGTTCTCAGTGGAAAGGGTGGAGTTGGAAAGAGCACGGTTGCAGTGAATCTAACTGCAG
CTTTAGCTAAGATGGGATACTTTGTTGGAATCTTGGATGCAGATATTCACGGCCCAAACGTTGCAAAGATGTTCGGAATT
GGAAACACCGATATCTATGCCGAGAAGTTTGAGGACGGACACTTCGAAATGATTCCTCCAACGGTGGACTTCATGGGCCA
AGTTACTCCAATAAAGGTTATGAGCATGGGCATGATGGTTCCCGAGGATCAACCCATAATATGGCGTGGCTCCCTAGTTA
CAAAGGCCATAAAGCAGCTTTTGGGAGACGTTATGTGGGGAGAACTTGACTTCATGATCATCGACTTCCCCCCTGGGACA
GGAGATGAGATTCTAACTGTAGTTCAATCCATCCAGCTTGACGCCGCAATAGTAGTAACAACCCCGCAAGAGGTGGCCCT
CCTCGATACTGGAAAAGCAGTTAATATGATGAAGAAGATGGAAGTTCCTTACATAGCAGTGATTGAAAACATGAGCTATC
TAATTTGCCCACACTGTGGAAATAAAATCGACATATTTGGGGAAGGAGGGGGAGAGAAGCTCGCAGAAAAGGAAGGTGTT
GACTTCTTAGGCAAAGTTCCAATAGACCTAAAAGCGAGAGAGGCTAGCGACCTGGGAATTCCAATAGTTCTGTATGGAGA
CACTCCAGCTGCCAAGGCATTCATGGAGATAGCCGAAAAGCTTGTTAATAAGCTCAAGGAAATAAAGGGCGATGGAAGAG
AGAAGTAA

Upstream 100 bases:

>100_bases
AAGATTATTGGCCTTCGGACGTTACACACATTTGTTCCATAAGATACAAATTGTAGCAAAGCTTTTTAACTCTCCTCCTT
ACCTATGATGGGTGAAGTAA

Downstream 100 bases:

>100_bases
GGGAGTTGCTTTGGCTTTAGTGGGAATGATACTTTACGGCCTTGAACCCGTGATAATAAGCTACAACCCAGTTAATCCCA
TAAGTTTTGCCTTTTTCTCA

Product: Mrp/Nbp35 family ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTIKAPTLNVPGLGVDPLTQRIKEKEKKWKYKIAVLSGKGGVGKSTVAVNLTAALAKMGYFVGILDADIHGPNVAKMFGI
GNTDIYAEKFEDGHFEMIPPTVDFMGQVTPIKVMSMGMMVPEDQPIIWRGSLVTKAIKQLLGDVMWGELDFMIIDFPPGT
GDEILTVVQSIQLDAAIVVTTPQEVALLDTGKAVNMMKKMEVPYIAVIENMSYLICPHCGNKIDIFGEGGGEKLAEKEGV
DFLGKVPIDLKAREASDLGIPIVLYGDTPAAKAFMEIAEKLVNKLKEIKGDGREK

Sequences:

>Translated_295_residues
MTIKAPTLNVPGLGVDPLTQRIKEKEKKWKYKIAVLSGKGGVGKSTVAVNLTAALAKMGYFVGILDADIHGPNVAKMFGI
GNTDIYAEKFEDGHFEMIPPTVDFMGQVTPIKVMSMGMMVPEDQPIIWRGSLVTKAIKQLLGDVMWGELDFMIIDFPPGT
GDEILTVVQSIQLDAAIVVTTPQEVALLDTGKAVNMMKKMEVPYIAVIENMSYLICPHCGNKIDIFGEGGGEKLAEKEGV
DFLGKVPIDLKAREASDLGIPIVLYGDTPAAKAFMEIAEKLVNKLKEIKGDGREK
>Mature_294_residues
TIKAPTLNVPGLGVDPLTQRIKEKEKKWKYKIAVLSGKGGVGKSTVAVNLTAALAKMGYFVGILDADIHGPNVAKMFGIG
NTDIYAEKFEDGHFEMIPPTVDFMGQVTPIKVMSMGMMVPEDQPIIWRGSLVTKAIKQLLGDVMWGELDFMIIDFPPGTG
DEILTVVQSIQLDAAIVVTTPQEVALLDTGKAVNMMKKMEVPYIAVIENMSYLICPHCGNKIDIFGEGGGEKLAEKEGVD
FLGKVPIDLKAREASDLGIPIVLYGDTPAAKAFMEIAEKLVNKLKEIKGDGREK

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family

Homologues:

Organism=Homo sapiens, GI157384956, Length=260, Percent_Identity=42.6923076923077, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI118572611, Length=284, Percent_Identity=39.0845070422535, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI6912540, Length=259, Percent_Identity=36.6795366795367, Blast_Score=174, Evalue=8e-44,
Organism=Escherichia coli, GI87082045, Length=262, Percent_Identity=41.6030534351145, Blast_Score=195, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI25143050, Length=275, Percent_Identity=37.0909090909091, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322188, Length=261, Percent_Identity=39.8467432950192, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321347, Length=283, Percent_Identity=38.86925795053, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI221511043, Length=264, Percent_Identity=37.8787878787879, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667611, Length=259, Percent_Identity=41.3127413127413, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI19921440, Length=255, Percent_Identity=39.6078431372549, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1145_PYRFU (Q8U1R0)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578874.1
- ProteinModelPortal:   Q8U1R0
- SMR:   Q8U1R0
- EnsemblBacteria:   EBPYRT00000006032
- GeneID:   1469014
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1145
- NMPDR:   fig|186497.1.peg.1185
- GeneTree:   EBGT00050000022661
- HOGENOM:   HBG586485
- OMA:   SYLICPH
- ProtClustDB:   CLSK253375
- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR000808

Pfam domain/function: PF09140 MipZ; PF10609 ParA

EC number: NA

Molecular weight: Translated: 32010; Mature: 31879

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKAPTLNVPGLGVDPLTQRIKEKEKKWKYKIAVLSGKGGVGKSTVAVNLTAALAKMGY
CEECCCCCCCCCCCCCHHHHHHHHHHHCEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHH
FVGILDADIHGPNVAKMFGIGNTDIYAEKFEDGHFEMIPPTVDFMGQVTPIKVMSMGMMV
EEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCEEECCCCHHHHCCCCCCHHHECCCCC
PEDQPIIWRGSLVTKAIKQLLGDVMWGELDFMIIDFPPGTGDEILTVVQSIQLDAAIVVT
CCCCCEEEECHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
TPQEVALLDTGKAVNMMKKMEVPYIAVIENMSYLICPHCGNKIDIFGEGGGEKLAEKEGV
CCCCEEEEECCHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCHHHHHCCC
DFLGKVPIDLKAREASDLGIPIVLYGDTPAAKAFMEIAEKLVNKLKEIKGDGREK
CEECCCCCEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TIKAPTLNVPGLGVDPLTQRIKEKEKKWKYKIAVLSGKGGVGKSTVAVNLTAALAKMGY
EECCCCCCCCCCCCCHHHHHHHHHHHCEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHH
FVGILDADIHGPNVAKMFGIGNTDIYAEKFEDGHFEMIPPTVDFMGQVTPIKVMSMGMMV
EEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCEEECCCCHHHHCCCCCCHHHECCCCC
PEDQPIIWRGSLVTKAIKQLLGDVMWGELDFMIIDFPPGTGDEILTVVQSIQLDAAIVVT
CCCCCEEEECHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
TPQEVALLDTGKAVNMMKKMEVPYIAVIENMSYLICPHCGNKIDIFGEGGGEKLAEKEGV
CCCCEEEEECCHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCHHHHHCCC
DFLGKVPIDLKAREASDLGIPIVLYGDTPAAKAFMEIAEKLVNKLKEIKGDGREK
CEECCCCCEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA