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The map label for this gene is asd [H]

Identifier: 18977428

GI number: 18977428

Start: 1010252

End: 1011256

Strand: Direct

Name: asd [H]

Synonym: PF1056

Alternate gene names: 18977428

Gene position: 1010252-1011256 (Clockwise)

Preceding gene: 18977427

Following gene: 18977429

Centisome position: 52.94

GC content: 41.69

Gene sequence:

>1005_bases
ATGAAAGCAGCCGTTTTAGGAGCAACTGGACTCGTAGGAAGGACTTTCGTGAAATTACTCAGCGGACACCCATGGTTTAA
AGTCAGTAAGCTTGTAGCATCTGAAAAGTCTGCAGGTAAGGAGTACGGAGAAATAGTCGAGGACTCACCAAAAGAGTTTA
GAAAAAATGTAATAATCAGCCTAGAGGAGTTTTTAAAAGACCCCGATGTTGATATAGTCTTCAATGCTCTCCCAGCCTCA
ATATCCAGAGAAGTTGAAGAAAAACTTGCGCAAGAGATTCCAGTTTTTACAAATGCTAGAGCTCACAGATATGACGAAGA
TGTTCCTATTTTGGTTCCAGAGGTAAACATGAATCACCTGGGAATAATTGAAGTTCAGAAAAAGAACAGGGGTTGGGATG
GTTTTATAGTCACAAACCCCAACTGTTCAACTGCTATACTTACGGTATCTTTAGCTCCATTAGTTGAATTTGGGATAAAG
AAGGTTAGAGTTGCAACAATGCAAGCTATTAGTGGAGCTGGATTTTCAGGACTTTCGGCATATGCAATTCATGACAATGT
AATTCCCTTCATAAATGGAGAGGAGTGGAAGATAGAAAATGAGAGCAAGAAAATATTGGGAAAATTCAACGGTGAGAGAA
TAGAAAACGCAGACTTCGACATCTCTGCCATAGCAACGAGAGTTCCAGTTATTCATGGTCATACGGAGGCAGTATTTGTG
GAGTTGGAGAAGGTAAACATTGAAGAGATAAGAGAAGCATTTGACAGCTTTGATCCATTGAGAGACTATAAGCTCCCCTC
TTATGAGAAACCGATAGTATATTCAGAAGTTCCACAACCCAGACTTCACAGGGATAGGGGGAAAGGACTAACTGGAACTG
TAGGTAGACTCGAGAAAATAAACGGTGGAGTGAAGTACGTAACACTTGGTCATAATCTCGTCAGAGGAGCGGCTGGAGGT
TCAGTTCTCAACGCTGAACTCGCCTACAGGCTTGGCTATCTCTGA

Upstream 100 bases:

>100_bases
CAACTGGACATGGGCTAAAAGATCCAAATATCGTCATAAAGAACTTCCAAGTTCCAGAACCTATAGACCCAACTTTAGAA
GCTTTTAAGGAGGTGATTGA

Downstream 100 bases:

>100_bases
TTATTTTTATTTTCTTTAGGTTCCATACTACAAGCCTTTAGGCAGTTCTGAAACTAGCGACAACAAGCCCTTCAGGACAA
TTAGAACATTCACGTTTCCA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKAAVLGATGLVGRTFVKLLSGHPWFKVSKLVASEKSAGKEYGEIVEDSPKEFRKNVIISLEEFLKDPDVDIVFNALPAS
ISREVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNMNHLGIIEVQKKNRGWDGFIVTNPNCSTAILTVSLAPLVEFGIK
KVRVATMQAISGAGFSGLSAYAIHDNVIPFINGEEWKIENESKKILGKFNGERIENADFDISAIATRVPVIHGHTEAVFV
ELEKVNIEEIREAFDSFDPLRDYKLPSYEKPIVYSEVPQPRLHRDRGKGLTGTVGRLEKINGGVKYVTLGHNLVRGAAGG
SVLNAELAYRLGYL

Sequences:

>Translated_334_residues
MKAAVLGATGLVGRTFVKLLSGHPWFKVSKLVASEKSAGKEYGEIVEDSPKEFRKNVIISLEEFLKDPDVDIVFNALPAS
ISREVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNMNHLGIIEVQKKNRGWDGFIVTNPNCSTAILTVSLAPLVEFGIK
KVRVATMQAISGAGFSGLSAYAIHDNVIPFINGEEWKIENESKKILGKFNGERIENADFDISAIATRVPVIHGHTEAVFV
ELEKVNIEEIREAFDSFDPLRDYKLPSYEKPIVYSEVPQPRLHRDRGKGLTGTVGRLEKINGGVKYVTLGHNLVRGAAGG
SVLNAELAYRLGYL
>Mature_334_residues
MKAAVLGATGLVGRTFVKLLSGHPWFKVSKLVASEKSAGKEYGEIVEDSPKEFRKNVIISLEEFLKDPDVDIVFNALPAS
ISREVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNMNHLGIIEVQKKNRGWDGFIVTNPNCSTAILTVSLAPLVEFGIK
KVRVATMQAISGAGFSGLSAYAIHDNVIPFINGEEWKIENESKKILGKFNGERIENADFDISAIATRVPVIHGHTEAVFV
ELEKVNIEEIREAFDSFDPLRDYKLPSYEKPIVYSEVPQPRLHRDRGKGLTGTVGRLEKINGGVKYVTLGHNLVRGAAGG
SVLNAELAYRLGYL

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=355, Percent_Identity=38.0281690140845, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36894; Mature: 36894

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVLGATGLVGRTFVKLLSGHPWFKVSKLVASEKSAGKEYGEIVEDSPKEFRKNVIIS
CCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHEE
LEEFLKDPDVDIVFNALPASISREVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNMNHL
HHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCE
GIIEVQKKNRGWDGFIVTNPNCSTAILTVSLAPLVEFGIKKVRVATMQAISGAGFSGLSA
EEEEEECCCCCCCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
YAIHDNVIPFINGEEWKIENESKKILGKFNGERIENADFDISAIATRVPVIHGHTEAVFV
EEEECCCCCEECCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCEEECCCEEEEE
ELEKVNIEEIREAFDSFDPLRDYKLPSYEKPIVYSEVPQPRLHRDRGKGLTGTVGRLEKI
EEECCCHHHHHHHHHCCCCHHCCCCCCCCCCEEECCCCCCHHHHHCCCCCCCHHHHHHHC
NGGVKYVTLGHNLVRGAAGGSVLNAELAYRLGYL
CCCEEEEEECCHHHHCCCCCCEEHHHHHHHHCCC
>Mature Secondary Structure
MKAAVLGATGLVGRTFVKLLSGHPWFKVSKLVASEKSAGKEYGEIVEDSPKEFRKNVIIS
CCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHEE
LEEFLKDPDVDIVFNALPASISREVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNMNHL
HHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCE
GIIEVQKKNRGWDGFIVTNPNCSTAILTVSLAPLVEFGIKKVRVATMQAISGAGFSGLSA
EEEEEECCCCCCCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
YAIHDNVIPFINGEEWKIENESKKILGKFNGERIENADFDISAIATRVPVIHGHTEAVFV
EEEECCCCCEECCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCEEECCCEEEEE
ELEKVNIEEIREAFDSFDPLRDYKLPSYEKPIVYSEVPQPRLHRDRGKGLTGTVGRLEKI
EEECCCHHHHHHHHHCCCCHHCCCCCCCCCCEEECCCCCCHHHHHCCCCCCCHHHHHHHC
NGGVKYVTLGHNLVRGAAGGSVLNAELAYRLGYL
CCCEEEEEECCHHHHCCCCCCEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]