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The map label for this gene is rfk

Identifier: 18977360

GI number: 18977360

Start: 941910

End: 942548

Strand: Direct

Name: rfk

Synonym: PF0988

Alternate gene names: 18977360

Gene position: 941910-942548 (Clockwise)

Preceding gene: 18977359

Following gene: 18977361

Centisome position: 49.36

GC content: 37.72

Gene sequence:

>639_bases
GTGAAAAAGAGTAACCTTGATTTGTTAATCCTCCTTGCAAAGGCAGGGGGGATAGAGAAAGAGATTCTAACGACTTCTAG
AGAACTTAGTAAAATGTTAAACGTTTCTCCTCAAACGATAGTTAGATGGTTAGAAGATCTCGAAAAAGATGGGCTAATAA
AGAAAAGTGAATCAAGGAAAGGAACTTTAGTTACAATCACCGAAGAAGGAGTTAAGTTTTTGGAAAAACTACACGAGGAA
TTATCAGATGCTCTTTACAGAGGAATTATAATTGGAGAAGTTGTTTCTGGAATCGGAGAGGGTGCTTACTATGTTAGACA
ATATGCCCCCTTAATACGAGAGTACCTGGGATTTGACCCATACCCTGGAACATTAAACGTCAGAGTAATATTCCCAAAGA
CCATATTCGATGCACTTTGCAATGTTAGGCCTATTATAATTCCGGGATTTACAAAAGAAGGGAGAACCTTTGGAGACGTG
AGGGCATATAGAGTTAAAATCGATAATATCGAAGGTGCAATAGTGATCCCCTCAAGAACAATTCATCCTCCAAAAATCGC
TGAAATAATAGCTCCCGTGAATTTAAGAAAAACCCTCAACTTAAAGGATGGTGATAGAATTAGAATCAAAACCCTTTGA

Upstream 100 bases:

>100_bases
CTCAATGATGCTGTCAGAATTGTAGAAAAATTGCTAGATGAAAACGGTTATCCAAAGCCCTTAAATATAGCCGACAAACT
CTCCAAAAGAGGTGAGTCTC

Downstream 100 bases:

>100_bases
GGGCCCGGCTTATCCGCCCGCCTTCATCGTCTGCCCTTCTCGGCTCCCTCAGGCGGCCCCGAAGGCCGGGCCCTGTCCGC
CCGGAGACGTCACCTCGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: RFK; CTP-dependent riboflavin kinase; CTP:riboflavin 5'-phosphotransferase; Flavokinase

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKKSNLDLLILLAKAGGIEKEILTTSRELSKMLNVSPQTIVRWLEDLEKDGLIKKSESRKGTLVTITEEGVKFLEKLHEE
LSDALYRGIIIGEVVSGIGEGAYYVRQYAPLIREYLGFDPYPGTLNVRVIFPKTIFDALCNVRPIIIPGFTKEGRTFGDV
RAYRVKIDNIEGAIVIPSRTIHPPKIAEIIAPVNLRKTLNLKDGDRIRIKTL

Sequences:

>Translated_212_residues
MKKSNLDLLILLAKAGGIEKEILTTSRELSKMLNVSPQTIVRWLEDLEKDGLIKKSESRKGTLVTITEEGVKFLEKLHEE
LSDALYRGIIIGEVVSGIGEGAYYVRQYAPLIREYLGFDPYPGTLNVRVIFPKTIFDALCNVRPIIIPGFTKEGRTFGDV
RAYRVKIDNIEGAIVIPSRTIHPPKIAEIIAPVNLRKTLNLKDGDRIRIKTL
>Mature_212_residues
MKKSNLDLLILLAKAGGIEKEILTTSRELSKMLNVSPQTIVRWLEDLEKDGLIKKSESRKGTLVTITEEGVKFLEKLHEE
LSDALYRGIIIGEVVSGIGEGAYYVRQYAPLIREYLGFDPYPGTLNVRVIFPKTIFDALCNVRPIIIPGFTKEGRTFGDV
RAYRVKIDNIEGAIVIPSRTIHPPKIAEIIAPVNLRKTLNLKDGDRIRIKTL

Specific function: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)

COG id: COG1339

COG function: function code KH; Transcriptional regulator of a riboflavin/FAD biosynthetic operon

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal riboflavin kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIFK_PYRFU (Q8U262)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578717.1
- ProteinModelPortal:   Q8U262
- SMR:   Q8U262
- EnsemblBacteria:   EBPYRT00000006014
- GeneID:   1468853
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0988
- NMPDR:   fig|186497.1.peg.1024
- GeneTree:   EBGT00050000023005
- HOGENOM:   HBG553349
- OMA:   REYLGFD
- ProtClustDB:   CLSK253495
- GO:   GO:0005622
- HAMAP:   MF_01285
- InterPro:   IPR000835
- InterPro:   IPR015865
- InterPro:   IPR002834
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.40.30.30
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF01982 CTP-dep_RFKase; PF01047 MarR

EC number: =2.7.1.161

Molecular weight: Translated: 23813; Mature: 23813

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50995 HTH_MARR_2

Important sites: BINDING 180-180 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSNLDLLILLAKAGGIEKEILTTSRELSKMLNVSPQTIVRWLEDLEKDGLIKKSESRK
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCC
GTLVTITEEGVKFLEKLHEELSDALYRGIIIGEVVSGIGEGAYYVRQYAPLIREYLGFDP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
YPGTLNVRVIFPKTIFDALCNVRPIIIPGFTKEGRTFGDVRAYRVKIDNIEGAIVIPSRT
CCCEEEEEEEEHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCEEEECCCC
IHPPKIAEIIAPVNLRKTLNLKDGDRIRIKTL
CCCHHHHHHHCCCCCCEEECCCCCCEEEEEEC
>Mature Secondary Structure
MKKSNLDLLILLAKAGGIEKEILTTSRELSKMLNVSPQTIVRWLEDLEKDGLIKKSESRK
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCC
GTLVTITEEGVKFLEKLHEELSDALYRGIIIGEVVSGIGEGAYYVRQYAPLIREYLGFDP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
YPGTLNVRVIFPKTIFDALCNVRPIIIPGFTKEGRTFGDVRAYRVKIDNIEGAIVIPSRT
CCCEEEEEEEEHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCEEEECCCC
IHPPKIAEIIAPVNLRKTLNLKDGDRIRIKTL
CCCHHHHHHHCCCCCCEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA