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The map label for this gene is 18977246

Identifier: 18977246

GI number: 18977246

Start: 847018

End: 848157

Strand: Direct

Name: 18977246

Synonym: PF0874

Alternate gene names: NA

Gene position: 847018-848157 (Clockwise)

Preceding gene: 18977241

Following gene: 18977247

Centisome position: 44.39

GC content: 41.58

Gene sequence:

>1140_bases
TTGCATGCCAACGTTGTTTTTCCACTTCCGGGGGGCCCTGTAATAAGGTACACCCTCCCGGGAATTAGTCCTCCCTCAAT
AAGTTCGTCAAGCCCTTTAACTCCAGTAGGTATTCTCTCGGCCACAGTGCTCATAGTTTTCCCGCCTTGTGTCCATAAGT
CTTTTTATGTGCTAAGGAATAAAACACTTTTGGTGAATAACATGAGCATTGGAGTATTTGATGCACACTCAGATTTACCC
ACATACATTTATGAAGAAAGGAAAAACGGAAAAACAAGAGTTTTAGAAGAAAAATTTGATGAGTTCTTTACTGGAATCTC
AGCGAGAGTTATGAGCATTTGGAGCAAGCCAGATAAGAGACCTATTATATTGAGGTATTCCCTTGAAGCCATCAATAGAT
TGTACTCAGACGTTGCAGAGAGCCAGAGATTTGAAATAGTGAGAAGCATAAAAGAGATGGAGGAAGCTATTAAAAATGAT
AAGGTGGCACTTTGGCTCGGCCTTGAGGGAGGAGAACCAATAGAAAGTCTTGATATCCTAGAGATATTTTACTCCCTGGG
ATTAAGAGTGCTGACATTAACTTGGAGCTTAAGAAATCAGATTGGAGACGGTGTTTTCGAGAGGACAAATGGAGGAATAA
CGAACTTTGGAGCTGAAGTCATTGGGAAATGTGAAGAGTTGGGGATCTTAATAGACGTAAGTCACCTTAATGAAGCTGGA
TTCTGGGACGTTCTTGACATTACTGGATTTCCAGTTATAGCTTCGCACTCAAACGCAAAATCACTCTGCGATAATCCAAG
GAACTTAACTGATGAGCAAATAAAGGCCATAGCTGAGAGAGATGGTGTTGTTGGAATTACAGCCGTTGCAGCCTTCGTAG
ATAAAGACAATCCAACACTTGAAAAGTTCATCGCCCACGTAGAGCATGTAGTTGACCTGGTAGGTTACAAGCACGTTGGA
TTTGGGTTTGATTTCGTATATTATCTCCCAGAGTGGAGCGGAAAGAGCGTGGTGGGGCTAGAAAATGAGAGAAGGATACC
TGATTTAATTGAGAGATTGAAGGAGAACTTCAGTGAAAAAGAAGTCAAGGCCATAGCATTCGACAACTTTAAGAGGGTAT
TTGATAGAGTTGTTGGATGA

Upstream 100 bases:

>100_bases
AGGGGTTAAATCTCGCTATATCTTTAGCAACTTCTTCGGGCTTATGAATGAGTGAAATGTATGCTCCTTTTTCTCCTCTT
CTAGCCCCTTCCAAAAGAAA

Downstream 100 bases:

>100_bases
TGTACTTCCTAACTTTCAGAGAGGCGAGGGAAATTCTGAAAGCCAAAAGAGAGGGTAAGGAGGAAGTTGAGGTTAACTTA
GACCTCATGAGGAGTAACAA

Product: membrane dipeptidase

Products: NA

Alternate protein names: ORF R [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MHANVVFPLPGGPVIRYTLPGISPPSISSSSPLTPVGILSATVLIVFPPCVHKSFYVLRNKTLLVNNMSIGVFDAHSDLP
TYIYEERKNGKTRVLEEKFDEFFTGISARVMSIWSKPDKRPIILRYSLEAINRLYSDVAESQRFEIVRSIKEMEEAIKND
KVALWLGLEGGEPIESLDILEIFYSLGLRVLTLTWSLRNQIGDGVFERTNGGITNFGAEVIGKCEELGILIDVSHLNEAG
FWDVLDITGFPVIASHSNAKSLCDNPRNLTDEQIKAIAERDGVVGITAVAAFVDKDNPTLEKFIAHVEHVVDLVGYKHVG
FGFDFVYYLPEWSGKSVVGLENERRIPDLIERLKENFSEKEVKAIAFDNFKRVFDRVVG

Sequences:

>Translated_379_residues
MHANVVFPLPGGPVIRYTLPGISPPSISSSSPLTPVGILSATVLIVFPPCVHKSFYVLRNKTLLVNNMSIGVFDAHSDLP
TYIYEERKNGKTRVLEEKFDEFFTGISARVMSIWSKPDKRPIILRYSLEAINRLYSDVAESQRFEIVRSIKEMEEAIKND
KVALWLGLEGGEPIESLDILEIFYSLGLRVLTLTWSLRNQIGDGVFERTNGGITNFGAEVIGKCEELGILIDVSHLNEAG
FWDVLDITGFPVIASHSNAKSLCDNPRNLTDEQIKAIAERDGVVGITAVAAFVDKDNPTLEKFIAHVEHVVDLVGYKHVG
FGFDFVYYLPEWSGKSVVGLENERRIPDLIERLKENFSEKEVKAIAFDNFKRVFDRVVG
>Mature_379_residues
MHANVVFPLPGGPVIRYTLPGISPPSISSSSPLTPVGILSATVLIVFPPCVHKSFYVLRNKTLLVNNMSIGVFDAHSDLP
TYIYEERKNGKTRVLEEKFDEFFTGISARVMSIWSKPDKRPIILRYSLEAINRLYSDVAESQRFEIVRSIKEMEEAIKND
KVALWLGLEGGEPIESLDILEIFYSLGLRVLTLTWSLRNQIGDGVFERTNGGITNFGAEVIGKCEELGILIDVSHLNEAG
FWDVLDITGFPVIASHSNAKSLCDNPRNLTDEQIKAIAERDGVVGITAVAAFVDKDNPTLEKFIAHVEHVVDLVGYKHVG
FGFDFVYYLPEWSGKSVVGLENERRIPDLIERLKENFSEKEVKAIAFDNFKRVFDRVVG

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=336, Percent_Identity=31.8452380952381, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4758190, Length=336, Percent_Identity=31.8452380952381, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI11641269, Length=382, Percent_Identity=29.0575916230367, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI193211608, Length=330, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI193211610, Length=330, Percent_Identity=27.5757575757576, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221475880, Length=342, Percent_Identity=28.6549707602339, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281362638, Length=344, Percent_Identity=28.4883720930233, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281362636, Length=344, Percent_Identity=28.4883720930233, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI161083233, Length=266, Percent_Identity=31.5789473684211, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356391, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000180
- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 42405; Mature: 42405

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHANVVFPLPGGPVIRYTLPGISPPSISSSSPLTPVGILSATVLIVFPPCVHKSFYVLRN
CCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHEEHEEECCHHCCCEEEEEC
KTLLVNNMSIGVFDAHSDLPTYIYEERKNGKTRVLEEKFDEFFTGISARVMSIWSKPDKR
CEEEEECCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIILRYSLEAINRLYSDVAESQRFEIVRSIKEMEEAIKNDKVALWLGLEGGEPIESLDIL
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
EIFYSLGLRVLTLTWSLRNQIGDGVFERTNGGITNFGAEVIGKCEELGILIDVSHLNEAG
HHHHHCCCEEEEHHHHHHHHHCCCHHHHCCCCCHHHHHHHHCCHHHCCEEEEECCCCCCC
FWDVLDITGFPVIASHSNAKSLCDNPRNLTDEQIKAIAERDGVVGITAVAAFVDKDNPTL
CEEEEECCCCCEEECCCCCHHHHCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHCCCCCHH
EKFIAHVEHVVDLVGYKHVGFGFDFVYYLPEWSGKSVVGLENERRIPDLIERLKENFSEK
HHHHHHHHHHHHHHCCHHCCCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHCCCHH
EVKAIAFDNFKRVFDRVVG
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHANVVFPLPGGPVIRYTLPGISPPSISSSSPLTPVGILSATVLIVFPPCVHKSFYVLRN
CCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHEEHEEECCHHCCCEEEEEC
KTLLVNNMSIGVFDAHSDLPTYIYEERKNGKTRVLEEKFDEFFTGISARVMSIWSKPDKR
CEEEEECCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIILRYSLEAINRLYSDVAESQRFEIVRSIKEMEEAIKNDKVALWLGLEGGEPIESLDIL
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
EIFYSLGLRVLTLTWSLRNQIGDGVFERTNGGITNFGAEVIGKCEELGILIDVSHLNEAG
HHHHHCCCEEEEHHHHHHHHHCCCHHHHCCCCCHHHHHHHHCCHHHCCEEEEECCCCCCC
FWDVLDITGFPVIASHSNAKSLCDNPRNLTDEQIKAIAERDGVVGITAVAAFVDKDNPTL
CEEEEECCCCCEEECCCCCHHHHCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHCCCCCHH
EKFIAHVEHVVDLVGYKHVGFGFDFVYYLPEWSGKSVVGLENERRIPDLIERLKENFSEK
HHHHHHHHHHHHHHCCHHCCCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHCCCHH
EVKAIAFDNFKRVFDRVVG
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2536663 [H]