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The map label for this gene is glmM

Identifier: 18977233

GI number: 18977233

Start: 835634

End: 836992

Strand: Direct

Name: glmM

Synonym: PF0861

Alternate gene names: 18977233

Gene position: 835634-836992 (Clockwise)

Preceding gene: 33359517

Following gene: 18977234

Centisome position: 43.79

GC content: 43.56

Gene sequence:

>1359_bases
ATGGGAAAATACTTTGGAACGAGCGGAATTAGGGAAGTGGTTAACGAAAAACTTACACCCGAGCTGGCTCTAAAGGTAGG
ACTGGCCCTGGGAACTTATCTTGGAGAGGGGAGAGTTGTTGTTGGGATTGATACTAGAACGAGCAGTGAAATGATAAAGC
ATGCCCTTGTAAGTGGCCTTTTGGCAACTGGAATCGAGGTTGTGGATATAGGACTTGCTCCTACTCCTCTAACGGGATTT
GCGATTAAGCTTTACAATGCAGATGCGGGAGTCACAATTACGGCCTCGCACAACCCTCCAAACTACAACGGTATCAAGGT
TTGGGACAGAAACGGAATGGCGTACACTCCAGATAAAGAGAGCGAGCTTGAGAGAATAATCGAAGAAGAAACCTTTAAGA
GAGTAAGTTGGATGGAGATAGGGGAAGTTATTAAAGCTGATCCTAAAAAGGAATACATTAAGAATGCAGTTGAGCAGATA
AACTTAGAGAATTCATATACAGTGGTAGTTGATAGCGGAAATGGGGCTGGATCAATAGTAAGCCCCTATCTTCAGAGAGA
GCTAGGGAACAAGGTAATTAGTCTAAATTCACACCCAACGGGCTTCTTTGTTAGAGAACTTGAGCCAAATAGAAAGAGCT
TAGATATGCTGTCTAAAGTAGTTAGGGAAGTTGGGGCTGATGTTGGAATAGCTCACGATGGAGATGCAGATAGAATTGGT
GTGGTGGATGACCAAGGGAACTTCGTAGATTATGAGGTCATGCTTTCGCTGATAGCGGGATATATGATTGAAAAGTACGG
AAAGGGCAAAGTTGTGACAACCGTTGACGCAGGATTTGCCCTCGATGATTACCTAAAGCCCAGGGGTGGAGAAGTTATTA
GAACAAAGGTTGGCGATGTTGCTGTTGCATATGAGCTCAGCAAACATGGAGGTGTATTTGGAGGGGAGCCAAGTGGTACT
TGGATAATCCCTCAGTGGAACTTAACTCCTGATGGCATCTTTGCTGGAGCGTTAGTGGTTGAGATGATTGACAAATTAGG
CCCAATAAGCGAGCTTGCAAAAGAAGTTCCCAGGTATGTGACGCTTAGGGAGAAAATTCCCTGTCCAAATGAGCTAAAGC
AGAAGGTCATGCGTATAATTGAAAAGCTGGCTCTTCAAAACTTTGAATACAAGAATTTAATTGACATTGATGGAATAAGA
ATTGAAAATGAGGAGTGGTGGATACTCTTTAGGCCGAGCGGAACTGAGCCAATAATGAGGATAACCCTTGAAGCTCATAC
AAAAGAAAAAGCTGAAGAGCTGATGAAGAAGGCGAGGGGACTAGTTAAGGAAGCAATTGAAAAGGCCAAGCTTTCTTAG

Upstream 100 bases:

>100_bases
GAACCTGGGTAAAAGAAAATGGCAAAATTAACAATCCCGTCTCACTTGAAAGAGCAAAAATCCTCGTAAGGATGAAAAAC
AGCCTAATGGGGGTATAGCA

Downstream 100 bases:

>100_bases
CCCTTTAATTTTTTGAAGCCTAAGGCTTAGGGTATTTTTGAAGATAATATTTATTGTTAATGGCAATTAGAGTGGATGTA
ACAATACCAAATCCAATTCC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MGKYFGTSGIREVVNEKLTPELALKVGLALGTYLGEGRVVVGIDTRTSSEMIKHALVSGLLATGIEVVDIGLAPTPLTGF
AIKLYNADAGVTITASHNPPNYNGIKVWDRNGMAYTPDKESELERIIEEETFKRVSWMEIGEVIKADPKKEYIKNAVEQI
NLENSYTVVVDSGNGAGSIVSPYLQRELGNKVISLNSHPTGFFVRELEPNRKSLDMLSKVVREVGADVGIAHDGDADRIG
VVDDQGNFVDYEVMLSLIAGYMIEKYGKGKVVTTVDAGFALDDYLKPRGGEVIRTKVGDVAVAYELSKHGGVFGGEPSGT
WIIPQWNLTPDGIFAGALVVEMIDKLGPISELAKEVPRYVTLREKIPCPNELKQKVMRIIEKLALQNFEYKNLIDIDGIR
IENEEWWILFRPSGTEPIMRITLEAHTKEKAEELMKKARGLVKEAIEKAKLS

Sequences:

>Translated_452_residues
MGKYFGTSGIREVVNEKLTPELALKVGLALGTYLGEGRVVVGIDTRTSSEMIKHALVSGLLATGIEVVDIGLAPTPLTGF
AIKLYNADAGVTITASHNPPNYNGIKVWDRNGMAYTPDKESELERIIEEETFKRVSWMEIGEVIKADPKKEYIKNAVEQI
NLENSYTVVVDSGNGAGSIVSPYLQRELGNKVISLNSHPTGFFVRELEPNRKSLDMLSKVVREVGADVGIAHDGDADRIG
VVDDQGNFVDYEVMLSLIAGYMIEKYGKGKVVTTVDAGFALDDYLKPRGGEVIRTKVGDVAVAYELSKHGGVFGGEPSGT
WIIPQWNLTPDGIFAGALVVEMIDKLGPISELAKEVPRYVTLREKIPCPNELKQKVMRIIEKLALQNFEYKNLIDIDGIR
IENEEWWILFRPSGTEPIMRITLEAHTKEKAEELMKKARGLVKEAIEKAKLS
>Mature_451_residues
GKYFGTSGIREVVNEKLTPELALKVGLALGTYLGEGRVVVGIDTRTSSEMIKHALVSGLLATGIEVVDIGLAPTPLTGFA
IKLYNADAGVTITASHNPPNYNGIKVWDRNGMAYTPDKESELERIIEEETFKRVSWMEIGEVIKADPKKEYIKNAVEQIN
LENSYTVVVDSGNGAGSIVSPYLQRELGNKVISLNSHPTGFFVRELEPNRKSLDMLSKVVREVGADVGIAHDGDADRIGV
VDDQGNFVDYEVMLSLIAGYMIEKYGKGKVVTTVDAGFALDDYLKPRGGEVIRTKVGDVAVAYELSKHGGVFGGEPSGTW
IIPQWNLTPDGIFAGALVVEMIDKLGPISELAKEVPRYVTLREKIPCPNELKQKVMRIIEKLALQNFEYKNLIDIDGIRI
ENEEWWILFRPSGTEPIMRITLEAHTKEKAEELMKKARGLVKEAIEKAKLS

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=461, Percent_Identity=31.8872017353579, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788361, Length=437, Percent_Identity=28.3752860411899, Blast_Score=158, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_PYRFU (Q8U2H4)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578590.1
- HSSP:   O58651
- ProteinModelPortal:   Q8U2H4
- SMR:   Q8U2H4
- EnsemblBacteria:   EBPYRT00000004679
- GeneID:   1468720
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0861
- NMPDR:   fig|186497.1.peg.891
- GeneTree:   EBGT00050000022330
- HOGENOM:   HBG644964
- OMA:   WIFPKIS
- ProtClustDB:   PRK14321
- HAMAP:   MF_01554_A
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49820; Mature: 49689

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYFGTSGIREVVNEKLTPELALKVGLALGTYLGEGRVVVGIDTRTSSEMIKHALVSGL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHHHH
LATGIEVVDIGLAPTPLTGFAIKLYNADAGVTITASHNPPNYNGIKVWDRNGMAYTPDKE
HHCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEECCCCEECCCCH
SELERIIEEETFKRVSWMEIGEVIKADPKKEYIKNAVEQINLENSYTVVVDSGNGAGSIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
SPYLQRELGNKVISLNSHPTGFFVRELEPNRKSLDMLSKVVREVGADVGIAHDGDADRIG
HHHHHHHHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VVDDQGNFVDYEVMLSLIAGYMIEKYGKGKVVTTVDAGFALDDYLKPRGGEVIRTKVGDV
EEECCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCEEEEECCCE
AVAYELSKHGGVFGGEPSGTWIIPQWNLTPDGIFAGALVVEMIDKLGPISELAKEVPRYV
EEEEEEHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCHHHE
TLREKIPCPNELKQKVMRIIEKLALQNFEYKNLIDIDGIRIENEEWWILFRPSGTEPIMR
EHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCCEEEEECCCCCCCEEE
ITLEAHTKEKAEELMKKARGLVKEAIEKAKLS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKYFGTSGIREVVNEKLTPELALKVGLALGTYLGEGRVVVGIDTRTSSEMIKHALVSGL
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHHHH
LATGIEVVDIGLAPTPLTGFAIKLYNADAGVTITASHNPPNYNGIKVWDRNGMAYTPDKE
HHCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEECCCCEECCCCH
SELERIIEEETFKRVSWMEIGEVIKADPKKEYIKNAVEQINLENSYTVVVDSGNGAGSIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
SPYLQRELGNKVISLNSHPTGFFVRELEPNRKSLDMLSKVVREVGADVGIAHDGDADRIG
HHHHHHHHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VVDDQGNFVDYEVMLSLIAGYMIEKYGKGKVVTTVDAGFALDDYLKPRGGEVIRTKVGDV
EEECCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCEEEEECCCE
AVAYELSKHGGVFGGEPSGTWIIPQWNLTPDGIFAGALVVEMIDKLGPISELAKEVPRYV
EEEEEEHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCHHHE
TLREKIPCPNELKQKVMRIIEKLALQNFEYKNLIDIDGIRIENEEWWILFRPSGTEPIMR
EHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCCEEEEECCCCCCCEEE
ITLEAHTKEKAEELMKKARGLVKEAIEKAKLS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA