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The map label for this gene is arsC [H]

Identifier: 18976925

GI number: 18976925

Start: 570148

End: 570597

Strand: Direct

Name: arsC [H]

Synonym: PF0553

Alternate gene names: 18976925

Gene position: 570148-570597 (Clockwise)

Preceding gene: 18976923

Following gene: 18976926

Centisome position: 29.88

GC content: 39.11

Gene sequence:

>450_bases
ATGGAGGAAAAAATCATCCTATTTGTTTGCGTAAAGAACTCTGCAAGGAGTCAAATGGCAGAGGCATTCTTCAATTATTA
TAACGATGATCCAAGATTTAAAGCAATGAGCGCTGGGACTGAGCCAGCTGATGACATTGATCCCCTAGCAAAGAAGGTCA
TGGAGGAAATAGGAATTTCTTTAGAGGGGCAAAAACCAAAGCTTTATACTCCGGAAATGGCAGATAAAGCTTACATTGTC
ATAACAATGGGATGTCTAGATAAATGTCCATATGCCCCACCTGAAAAGACTTGGGATTGGGGACTGGAAGATCCTTATGG
AAAGCCAATAGAAAAGTATCGAGAAGTTAGAGATGAGATAAAGCGTCGTGTTCTAAAGCTTATAGAGGATTTAAAAGCTG
GAAAGAGTAGAGAGGAAATTATAGGAAGAAAAAGCTTGTTTGCCATTTAA

Upstream 100 bases:

>100_bases
CTTTCCTAAACCAATGGTTGTAAGGTTCTATATAGCTCAATATATCCTCTATTGAAAAACGCTTTAAGCTACAAAATCTC
TTTATGCTTAGGGGGTAATT

Downstream 100 bases:

>100_bases
ATCTTCTTAAAAGATTGAGGTTGATCTTGAAGACATCTTGCGAGGGCGGAAACATTTACATTAGAAAGACGTGAAAGTTT
TGAAAAATCCTTACAAGAAT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MEEKIILFVCVKNSARSQMAEAFFNYYNDDPRFKAMSAGTEPADDIDPLAKKVMEEIGISLEGQKPKLYTPEMADKAYIV
ITMGCLDKCPYAPPEKTWDWGLEDPYGKPIEKYREVRDEIKRRVLKLIEDLKAGKSREEIIGRKSLFAI

Sequences:

>Translated_149_residues
MEEKIILFVCVKNSARSQMAEAFFNYYNDDPRFKAMSAGTEPADDIDPLAKKVMEEIGISLEGQKPKLYTPEMADKAYIV
ITMGCLDKCPYAPPEKTWDWGLEDPYGKPIEKYREVRDEIKRRVLKLIEDLKAGKSREEIIGRKSLFAI
>Mature_149_residues
MEEKIILFVCVKNSARSQMAEAFFNYYNDDPRFKAMSAGTEPADDIDPLAKKVMEEIGISLEGQKPKLYTPEMADKAYIV
ITMGCLDKCPYAPPEKTWDWGLEDPYGKPIEKYREVRDEIKRRVLKLIEDLKAGKSREEIIGRKSLFAI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17129; Mature: 17129

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKIILFVCVKNSARSQMAEAFFNYYNDDPRFKAMSAGTEPADDIDPLAKKVMEEIGIS
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCC
LEGQKPKLYTPEMADKAYIVITMGCLDKCPYAPPEKTWDWGLEDPYGKPIEKYREVRDEI
CCCCCCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KRRVLKLIEDLKAGKSREEIIGRKSLFAI
HHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEEKIILFVCVKNSARSQMAEAFFNYYNDDPRFKAMSAGTEPADDIDPLAKKVMEEIGIS
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCC
LEGQKPKLYTPEMADKAYIVITMGCLDKCPYAPPEKTWDWGLEDPYGKPIEKYREVRDEI
CCCCCCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KRRVLKLIEDLKAGKSREEIIGRKSLFAI
HHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA