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The map label for this gene is hypD [C]

Identifier: 18976921

GI number: 18976921

Start: 566870

End: 567973

Strand: Direct

Name: hypD [C]

Synonym: PF0549

Alternate gene names: 18976921

Gene position: 566870-567973 (Clockwise)

Preceding gene: 18976920

Following gene: 18976922

Centisome position: 29.71

GC content: 42.3

Gene sequence:

>1104_bases
ATGCTTGAAAAATTTGGAGACAAAGCTGTAGCTCAAAAGATTTTAGAAAAAATTAAAGAGGAAGCTAAAGGGATAGAAGA
GCTACGATTTATGCACGTTTGTGGGACTCATGAGGACACAGTAACTAGGAGTGGAATCAGATCACTTCTTCCAGAAAATG
TAAAAATCATGAGTGGCCCAGGATGTCCCGTCTGTATAACCCCCGTTGAGGACATAGTGAAGATGATGGAAATTATGAAA
GTTGCGAGAGAGGAGAGGGAAGAAATTATTCTCACTACTTTTGGTGACATGTATAGAATTCCAACTCCAATAGGAAGCTT
TGCAGACTTAAAGAGTCAGGGTTACGATGTGAGGATAGTTTACTCTATATACGACTCCTATAAAATAGCCAAGGAAAATC
CAGATAAGCTTGTAGTGCACTTTTCTCCTGGGTTTGAGACTACCGCCGCTCCAACAGCTGGAATGCTTGAGAGCATTGTG
GAAGAGGGGCTAGAGAACTTTAAGATTTATTCCGTTCATAGGTTAACCCCTCCTGCAGTTGAAGCTCTCCTAAATGCGGG
GACTGTTTTTCACGGTTTAATAGATCCTGGTCATGTCTCTACAATAATTGGGGTGAAAGGATGGGCGTATCTCACAGAAA
AGTTTGGAATTCCTCAAGTTGTGGCTGGCTTTGAGCCAGTTGATGTTTTACTCGGAATACTTATTCTCATTAGGCTTGTG
AAGAGGGGCGAAGCGAAAATAATCAACGAGTATAATAGAGTTGTAAAGTGGGAAGGAAATGTCAAGGCCCAAGAACTGAT
TTGGAAGTACTTTGAAGTTAAAGATGCAAAGTGGAGGGCCCTAGGAGTAATTCCAAGGAGCGGATTGGAACTTAAGAAAG
AGTGGAAGGAGCTAGAAATTAGAACTTATTACAATCCCGAGGTTCCAAAGCTCCCAGATCTTGAAAAAGGATGTCTCTGT
GGGGCAGTCCTTAGAGGATTAGCCTTACCGACCCAGTGCCAACACTTTGGAAAGACATGTACACCAAGACATCCGGTAGG
TCCTTGTATGGTTTCGTACGAAGGAACTTGTCACATATTTTACAAATATGGCGCCCTGATGTAG

Upstream 100 bases:

>100_bases
AGTTCACACTGGCTTTGCTATAGAAAAGTTAGATGAGAGGAGAGCTAGAGAAATTCTTGAAGCCTGGGAAGAAGTTTTCT
CAGTAATTGGGGGTGAGTAA

Downstream 100 bases:

>100_bases
TTTTTATTACGCAAAAGTAATATACCACTACAGCATAAACCCCAAATATGGATTATCGAAAAATTCTCGATATTCATCAT
AGTTTTGGTTGTTTTTTCAT

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MLEKFGDKAVAQKILEKIKEEAKGIEELRFMHVCGTHEDTVTRSGIRSLLPENVKIMSGPGCPVCITPVEDIVKMMEIMK
VAREEREEIILTTFGDMYRIPTPIGSFADLKSQGYDVRIVYSIYDSYKIAKENPDKLVVHFSPGFETTAAPTAGMLESIV
EEGLENFKIYSVHRLTPPAVEALLNAGTVFHGLIDPGHVSTIIGVKGWAYLTEKFGIPQVVAGFEPVDVLLGILILIRLV
KRGEAKIINEYNRVVKWEGNVKAQELIWKYFEVKDAKWRALGVIPRSGLELKKEWKELEIRTYYNPEVPKLPDLEKGCLC
GAVLRGLALPTQCQHFGKTCTPRHPVGPCMVSYEGTCHIFYKYGALM

Sequences:

>Translated_367_residues
MLEKFGDKAVAQKILEKIKEEAKGIEELRFMHVCGTHEDTVTRSGIRSLLPENVKIMSGPGCPVCITPVEDIVKMMEIMK
VAREEREEIILTTFGDMYRIPTPIGSFADLKSQGYDVRIVYSIYDSYKIAKENPDKLVVHFSPGFETTAAPTAGMLESIV
EEGLENFKIYSVHRLTPPAVEALLNAGTVFHGLIDPGHVSTIIGVKGWAYLTEKFGIPQVVAGFEPVDVLLGILILIRLV
KRGEAKIINEYNRVVKWEGNVKAQELIWKYFEVKDAKWRALGVIPRSGLELKKEWKELEIRTYYNPEVPKLPDLEKGCLC
GAVLRGLALPTQCQHFGKTCTPRHPVGPCMVSYEGTCHIFYKYGALM
>Mature_367_residues
MLEKFGDKAVAQKILEKIKEEAKGIEELRFMHVCGTHEDTVTRSGIRSLLPENVKIMSGPGCPVCITPVEDIVKMMEIMK
VAREEREEIILTTFGDMYRIPTPIGSFADLKSQGYDVRIVYSIYDSYKIAKENPDKLVVHFSPGFETTAAPTAGMLESIV
EEGLENFKIYSVHRLTPPAVEALLNAGTVFHGLIDPGHVSTIIGVKGWAYLTEKFGIPQVVAGFEPVDVLLGILILIRLV
KRGEAKIINEYNRVVKWEGNVKAQELIWKYFEVKDAKWRALGVIPRSGLELKKEWKELEIRTYYNPEVPKLPDLEKGCLC
GAVLRGLALPTQCQHFGKTCTPRHPVGPCMVSYEGTCHIFYKYGALM

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=358, Percent_Identity=38.268156424581, Blast_Score=254, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41187; Mature: 41187

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKFGDKAVAQKILEKIKEEAKGIEELRFMHVCGTHEDTVTRSGIRSLLPENVKIMSGP
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECC
GCPVCITPVEDIVKMMEIMKVAREEREEIILTTFGDMYRIPTPIGSFADLKSQGYDVRIV
CCCEEECCHHHHHHHHHHHHHHHHHHHEEEEEECCCCEECCCCCCCHHHHHCCCCCEEEE
YSIYDSYKIAKENPDKLVVHFSPGFETTAAPTAGMLESIVEEGLENFKIYSVHRLTPPAV
EEECCCEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHH
EALLNAGTVFHGLIDPGHVSTIIGVKGWAYLTEKFGIPQVVAGFEPVDVLLGILILIRLV
HHHHHCCHHEECCCCCCHHHEEEECCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHH
KRGEAKIINEYNRVVKWEGNVKAQELIWKYFEVKDAKWRALGVIPRSGLELKKEWKELEI
HCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEE
RTYYNPEVPKLPDLEKGCLCGAVLRGLALPTQCQHFGKTCTPRHPVGPCMVSYEGTCHIF
EEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCEEEECCCCEEEE
YKYGALM
EECCCCC
>Mature Secondary Structure
MLEKFGDKAVAQKILEKIKEEAKGIEELRFMHVCGTHEDTVTRSGIRSLLPENVKIMSGP
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECC
GCPVCITPVEDIVKMMEIMKVAREEREEIILTTFGDMYRIPTPIGSFADLKSQGYDVRIV
CCCEEECCHHHHHHHHHHHHHHHHHHHEEEEEECCCCEECCCCCCCHHHHHCCCCCEEEE
YSIYDSYKIAKENPDKLVVHFSPGFETTAAPTAGMLESIVEEGLENFKIYSVHRLTPPAV
EEECCCEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHH
EALLNAGTVFHGLIDPGHVSTIIGVKGWAYLTEKFGIPQVVAGFEPVDVLLGILILIRLV
HHHHHCCHHEECCCCCCHHHEEEECCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHH
KRGEAKIINEYNRVVKWEGNVKAQELIWKYFEVKDAKWRALGVIPRSGLELKKEWKELEI
HCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEE
RTYYNPEVPKLPDLEKGCLCGAVLRGLALPTQCQHFGKTCTPRHPVGPCMVSYEGTCHIF
EEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCEEEECCCCEEEE
YKYGALM
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]