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The map label for this gene is adcA [H]

Identifier: 18976745

GI number: 18976745

Start: 387603

End: 388580

Strand: Direct

Name: adcA [H]

Synonym: PF0373

Alternate gene names: 18976745

Gene position: 387603-388580 (Clockwise)

Preceding gene: 18976744

Following gene: 18976746

Centisome position: 20.31

GC content: 42.02

Gene sequence:

>978_bases
ATGAGAAAAGCAGTAGTTCTCCTAATAGCGATTACTTTATTCGTTAGGCCGGTTATATCTCAAGAAAGAGAAAAACCACT
CGTTGTAACTAGCCTTCCTCCAGTTGCTTCAATAATAAAAGAGGCGCTAGGAGACAGTGTAGAAGTCGTTTATCTAGTCC
CTCCCGGCGTTGAGCCCCACCAATACCAGCTCTCCCCAGAGCAGATAGCACTGCTGAAGAATGCCGATGTAATAGTAACC
ACAGGTCATCTGCCAGCAGAGAATAAAATAATCGAGCTAAAGAGCGAAGGAAGCATAGAGGGAATTGTCTTAGAGCCTAA
AGATTACTCAGAATATGGGTTCAAATACCTACCAGAGAGGTGGTATGAGGGAAAGAATAACCCTCACGGAACATGGCTTG
ATCCAATGAACGCTCTAGCAATAGCTAAGGCAACTGCCGTTGCACTGTCCCAACTATATCCAGAGAAAGACCAAGAATTT
TCTAAAGCATTTGAAAGATTTGAGGAAAAGGTAACAACAATAATAAAGGCATATTCTTCCATAGCAAAGGATAAAAAGGC
CATAATAGAACTTCCATCTCAACAATATGCCCTTGAATGGTTGGGAATTGAGGTTATTAGCTCTATAAAGCCCGAAGCAG
AAGGTCCAGCGAAATCCATAGATGAGCTCTCCACATTAAGGCCAGATATAATTGTTTATGATGAGAATACGCCAGACGTG
TTAAAAAATGCAGCCTATGAACTCTCAAACAGGCTAGGAGTTCCCCTGGCGAACATAACTGTGCTGTGGACGGATAAGAA
TTACACCGAAGTTCTAATCCAAAATTCAAAGTCAGTAATAGGTGCCCTAAAGGAAGAAAAGAAAGTTGTCGTTAAAGAAG
GTAACGAGAAAGTCCAGTACATAGCTATTTCTCTCTTAACGGGCCTAATAGTTGGAGTCTCCATAGGGGTTGTCATCAGG
AAGTGTCCAGTGTTCTGA

Upstream 100 bases:

>100_bases
GGAAATAATAAAAAGTGAGGTCTTCCATATCCTAAAACATGCAAGAGAATGAAAAAGGCATAAAAACAATTAGGCTTTCC
TAATTTAAAGGGGAAGAAAA

Downstream 100 bases:

>100_bases
GGTAGATTTATATTCTCCCTTCCCAACTTTTATCCTTGGGATGAAAAGATGGAAATTGGAGTGGTAGGAAAACCAAATGT
AGGGAAATCAACATTCTTCT

Product: putative ABC transporter, periplasmic binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRKAVVLLIAITLFVRPVISQEREKPLVVTSLPPVASIIKEALGDSVEVVYLVPPGVEPHQYQLSPEQIALLKNADVIVT
TGHLPAENKIIELKSEGSIEGIVLEPKDYSEYGFKYLPERWYEGKNNPHGTWLDPMNALAIAKATAVALSQLYPEKDQEF
SKAFERFEEKVTTIIKAYSSIAKDKKAIIELPSQQYALEWLGIEVISSIKPEAEGPAKSIDELSTLRPDIIVYDENTPDV
LKNAAYELSNRLGVPLANITVLWTDKNYTEVLIQNSKSVIGALKEEKKVVVKEGNEKVQYIAISLLTGLIVGVSIGVVIR
KCPVF

Sequences:

>Translated_325_residues
MRKAVVLLIAITLFVRPVISQEREKPLVVTSLPPVASIIKEALGDSVEVVYLVPPGVEPHQYQLSPEQIALLKNADVIVT
TGHLPAENKIIELKSEGSIEGIVLEPKDYSEYGFKYLPERWYEGKNNPHGTWLDPMNALAIAKATAVALSQLYPEKDQEF
SKAFERFEEKVTTIIKAYSSIAKDKKAIIELPSQQYALEWLGIEVISSIKPEAEGPAKSIDELSTLRPDIIVYDENTPDV
LKNAAYELSNRLGVPLANITVLWTDKNYTEVLIQNSKSVIGALKEEKKVVVKEGNEKVQYIAISLLTGLIVGVSIGVVIR
KCPVF
>Mature_325_residues
MRKAVVLLIAITLFVRPVISQEREKPLVVTSLPPVASIIKEALGDSVEVVYLVPPGVEPHQYQLSPEQIALLKNADVIVT
TGHLPAENKIIELKSEGSIEGIVLEPKDYSEYGFKYLPERWYEGKNNPHGTWLDPMNALAIAKATAVALSQLYPEKDQEF
SKAFERFEEKVTTIIKAYSSIAKDKKAIIELPSQQYALEWLGIEVISSIKPEAEGPAKSIDELSTLRPDIIVYDENTPDV
LKNAAYELSNRLGVPLANITVLWTDKNYTEVLIQNSKSVIGALKEEKKVVVKEGNEKVQYIAISLLTGLIVGVSIGVVIR
KCPVF

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 36005; Mature: 36005

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAVVLLIAITLFVRPVISQEREKPLVVTSLPPVASIIKEALGDSVEVVYLVPPGVEPH
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEEEEEECCCCCCC
QYQLSPEQIALLKNADVIVTTGHLPAENKIIELKSEGSIEGIVLEPKDYSEYGFKYLPER
EEECCHHHHHEEECCCEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCHHHCHHHCCHH
WYEGKNNPHGTWLDPMNALAIAKATAVALSQLYPEKDQEFSKAFERFEEKVTTIIKAYSS
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAKDKKAIIELPSQQYALEWLGIEVISSIKPEAEGPAKSIDELSTLRPDIIVYDENTPDV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHH
LKNAAYELSNRLGVPLANITVLWTDKNYTEVLIQNSKSVIGALKEEKKVVVKEGNEKVQY
HHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHCEEEEECCCCHHHH
IAISLLTGLIVGVSIGVVIRKCPVF
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKAVVLLIAITLFVRPVISQEREKPLVVTSLPPVASIIKEALGDSVEVVYLVPPGVEPH
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEEEEEECCCCCCC
QYQLSPEQIALLKNADVIVTTGHLPAENKIIELKSEGSIEGIVLEPKDYSEYGFKYLPER
EEECCHHHHHEEECCCEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCHHHCHHHCCHH
WYEGKNNPHGTWLDPMNALAIAKATAVALSQLYPEKDQEFSKAFERFEEKVTTIIKAYSS
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAKDKKAIIELPSQQYALEWLGIEVISSIKPEAEGPAKSIDELSTLRPDIIVYDENTPDV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHH
LKNAAYELSNRLGVPLANITVLWTDKNYTEVLIQNSKSVIGALKEEKKVVVKEGNEKVQY
HHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHCEEEEECCCCHHHH
IAISLLTGLIVGVSIGVVIRKCPVF
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]