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The map label for this gene is moaB

Identifier: 18976744

GI number: 18976744

Start: 387045

End: 387554

Strand: Direct

Name: moaB

Synonym: PF0372

Alternate gene names: 18976744

Gene position: 387045-387554 (Clockwise)

Preceding gene: 18976743

Following gene: 18976745

Centisome position: 20.28

GC content: 41.57

Gene sequence:

>510_bases
ATGGGTGTTGAAGAGCACAAGAAGGAAGCACCAAAAACTTTCAAGTTTGGAGTTATAACGGTGAGCGATAAAGGGGCAAA
GGGAGAAAGAGAAGACAAAAGCGGTCCACTCATAATAGAGGAACTCTCTAAGCTGGGGGAACACGTTTACTACAAAATAG
TACCAGATGATAAGATCGAAGTATTAATAGCTCTTTTTGAGGCAATAAAGAGTGGAGCAGATGTAGTTGTAACTACGGGT
GGAACTGGAATAACAAGGAGGGACATAACGATAGAGTCCATAAAGCCCCTCTTTGATAAGGAGCTGAGCTTTGGAGAGGT
TTTTAGGGCCAAGAGTTATGAAGAAGTTGGGTATGCAACAGTTTTAACAAGAGCCACTGCAGGAATTATAAGAGGACAAG
AAAGGATAGTCGTCGTGTTTTCCCTTCCTGGGAGCGTTAATGCCGTAAAAACTGGACTGGAAATAATAAAAAGTGAGGTC
TTCCATATCCTAAAACATGCAAGAGAATGA

Upstream 100 bases:

>100_bases
CTATGGGCCTCTCTTGTGGGCTCTCTACAAGCTCTCAAAGGCTTCTTAATTTTCCTAAAACTTATTTAATTATTTTGCTG
AGTTTCTAGTGGTGGATAAC

Downstream 100 bases:

>100_bases
AAAAGGCATAAAAACAATTAGGCTTTCCTAATTTAAAGGGGAAGAAAAATGAGAAAAGCAGTAGTTCTCCTAATAGCGAT
TACTTTATTCGTTAGGCCGG

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: MPT adenylyltransferase

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MGVEEHKKEAPKTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVYYKIVPDDKIEVLIALFEAIKSGADVVVTTG
GTGITRRDITIESIKPLFDKELSFGEVFRAKSYEEVGYATVLTRATAGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEV
FHILKHARE

Sequences:

>Translated_169_residues
MGVEEHKKEAPKTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVYYKIVPDDKIEVLIALFEAIKSGADVVVTTG
GTGITRRDITIESIKPLFDKELSFGEVFRAKSYEEVGYATVLTRATAGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEV
FHILKHARE
>Mature_168_residues
GVEEHKKEAPKTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVYYKIVPDDKIEVLIALFEAIKSGADVVVTTGG
TGITRRDITIESIKPLFDKELSFGEVFRAKSYEEVGYATVLTRATAGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEVF
HILKHARE

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family

Homologues:

Organism=Escherichia coli, GI1787000, Length=145, Percent_Identity=37.2413793103448, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1786190, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564954, Length=156, Percent_Identity=35.2564102564103, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAB_PYRFU (Q8U3T3)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578101.1
- HSSP:   P30746
- ProteinModelPortal:   Q8U3T3
- SMR:   Q8U3T3
- EnsemblBacteria:   EBPYRT00000005387
- GeneID:   1468208
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0372
- NMPDR:   fig|186497.1.peg.379
- GeneTree:   EBGT00050000022469
- HOGENOM:   HBG460560
- OMA:   KKETGHI
- ProtClustDB:   CLSK253328
- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006443
- SMART:   SM00852
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 18574; Mature: 18442

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVEEHKKEAPKTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVYYKIVPDDKIE
CCCCHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCHHH
VLIALFEAIKSGADVVVTTGGTGITRRDITIESIKPLFDKELSFGEVFRAKSYEEVGYAT
HHHHHHHHHHCCCCEEEECCCCCCEECCEEHHHHHHHHHCCCCHHHHHHHCCHHHHHHHH
VLTRATAGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEVFHILKHARE
HHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GVEEHKKEAPKTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVYYKIVPDDKIE
CCCHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCHHH
VLIALFEAIKSGADVVVTTGGTGITRRDITIESIKPLFDKELSFGEVFRAKSYEEVGYAT
HHHHHHHHHHCCCCEEEECCCCCCEECCEEHHHHHHHHHCCCCHHHHHHHCCHHHHHHHH
VLTRATAGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEVFHILKHARE
HHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA